Erschienen in:
30.11.2015 | Case Report
Primary Malignant Melanoma of the Rectum: a Case Report of an Extremely Rare Gastrointestinal Cancer
verfasst von:
Laura Nunez Herrero, Benjamin Chaucer, Wahib Zafar, Fidencio Davalos, Shamim Salman, Sundee Naing
Erschienen in:
Journal of Gastrointestinal Cancer
|
Ausgabe 4/2016
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Excerpt
Primary anorectal malignant melanoma (ARMM) was first reported by Moore in 1857 [
1‐
3]. ARMM is a rare neoplasia and represents approximately 1 % of all malignant melanomas, approximately 23.8 % of mucosal melanomas, and between 0.5 and 2 % of all colorectal malignancies [
4‐
7]. The most common symptom is rectal bleeding, although patients can also complain of pain, a palpable mass, pruritus, tenesmus, and changes in bowel habit [
6‐
11]. Treatment is controversial and may include surgery, chemotherapy, or radiotherapy. Due to its rarity, prospective randomized trials are difficult to produce and have not yet demonstrated an ideal therapy [
4,
7‐
13]. The prognosis is very poor and survival may correlate with tumor invasion and/or the absence of metastasis at the time of diagnosis [
8,
11‐
16]. …
