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Langenbeck's Archives of Surgery
Erschienen in: Langenbeck's Archives of Surgery 3/2008

01.05.2008 | Original Article

Procalcitonin in preoperative diagnosis of abdominal sepsis

verfasst von: Nenad Ivančević, Dejan Radenković, Vesna Bumbaširević, Aleksandar Karamarković, Vasilije Jeremić, Nevena Kalezić, Tatjana Vodnik, Biljana Beleslin, Nataša Milić, Pavle Gregorić, Miloš Žarković

Erschienen in: Langenbeck's Archives of Surgery | Ausgabe 3/2008

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Abstract

Background and aims

The present study attempted to identify the diagnostic significance of procalcitonin (PCT) in acute abdominal conditions as well as the range of concentrations relating to diagnosis of abdominal sepsis.

Materials and methods

This was prospective clinical study. The study included 98 consecutive patients with acute abdominal conditions, divided in sepsis and systemic inflammatory response syndrome (SIRS) group.

Results

PCT concentrations on admission were significantly higher in the sepsis group than in the SIRS group (median [interquartile range] 2.32 [7.41] vs 0.45 ng/ml [2.62]). A cutoff value of 1.1 ng/ml yielded 72.4% sensitivity and 62.5% specificity. In a group of patients with abdominal symptoms lasting for more than 24 h, a cut-off value of 1.1 ng/ml yielded higher sensitivity (82.9%) and higher specificity (77.3%).

Conclusion

Our results suggest that PCT measurements may be useful for early, preoperative diagnosis of abdominal sepsis.
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Metadaten
Titel
Procalcitonin in preoperative diagnosis of abdominal sepsis
verfasst von
Nenad Ivančević
Dejan Radenković
Vesna Bumbaširević
Aleksandar Karamarković
Vasilije Jeremić
Nevena Kalezić
Tatjana Vodnik
Biljana Beleslin
Nataša Milić
Pavle Gregorić
Miloš Žarković
Publikationsdatum
01.05.2008
Verlag
Springer-Verlag
Erschienen in
Langenbeck's Archives of Surgery / Ausgabe 3/2008
Print ISSN: 1435-2443
Elektronische ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-007-0239-5

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