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Erschienen in: Current Oncology Reports 10/2017

01.10.2017 | Head and Neck Cancers (EY Hanna, Section Editor)

Prognostic Stratification of Patients With Advanced Oral Cavity Squamous Cell Carcinoma

verfasst von: Dante De Paz, Huang-Kai Kao, Yenlin Huang, Kai-Ping Chang

Erschienen in: Current Oncology Reports | Ausgabe 10/2017

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Abstract

Purpose of Review

Prognosis of advanced oral squamous cell carcinoma remains a challenge for clinicians despite progress in its diagnosis and treatment over the past decades. In this review, we assessed clinicopathological factors and potential biomarkers along with their prognostic relevance in an attempt to develop optimal treatment strategies for these patients.

Recent Findings

In addition to several pathologic factors that have been proposed to improve prognostic stratification and treatment planning in the eighth edition of the American Joint Committee staging manual on cancer, we reviewed some other imaging and clinicopathological parameters demonstrated to be closely associated with patient prognosis, along with the biomarkers related to novel target or immune therapy.

Summary

Evaluation of current literature regarding the prognostic stratification used in contemporary clinicopathological studies and progress in the development of targeted or immune therapy may help these patients benefit from tailored and personalized treatment and obtain better oncological results.
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Metadaten
Titel
Prognostic Stratification of Patients With Advanced Oral Cavity Squamous Cell Carcinoma
verfasst von
Dante De Paz
Huang-Kai Kao
Yenlin Huang
Kai-Ping Chang
Publikationsdatum
01.10.2017
Verlag
Springer US
Erschienen in
Current Oncology Reports / Ausgabe 10/2017
Print ISSN: 1523-3790
Elektronische ISSN: 1534-6269
DOI
https://doi.org/10.1007/s11912-017-0624-3

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