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Journal of Gastroenterology
Erschienen in: Journal of Gastroenterology 1/2019

22.09.2018 | Review

Progress in characterizing the linkage between Fusobacterium nucleatum and gastrointestinal cancer

verfasst von: Yang Liu, Yoshifumi Baba, Takatsugu Ishimoto, Masaaki Iwatsuki, Yukiharu Hiyoshi, Yuji Miyamoto, Naoya Yoshida, Rong Wu, Hideo Baba

Erschienen in: Journal of Gastroenterology | Ausgabe 1/2019

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Abstract

Microbiome research is a rapidly advancing field in human cancers. Fusobacterium nucleatum is an oral bacterium, indigenous to the human oral cavity, that plays a role in periodontal disease. Recent studies have found that F. nucleatum can promote gastrointestinal tumor progression and affect the prognosis of the disease. In addition, F. nucleatum may contribute to the chemo-resistance of gastrointestinal cancers. This review summarizes recent progress in the pathogenesis of F. nucleatum and its impact on gastrointestinal cancer.
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Metadaten
Titel
Progress in characterizing the linkage between Fusobacterium nucleatum and gastrointestinal cancer
verfasst von
Yang Liu
Yoshifumi Baba
Takatsugu Ishimoto
Masaaki Iwatsuki
Yukiharu Hiyoshi
Yuji Miyamoto
Naoya Yoshida
Rong Wu
Hideo Baba
Publikationsdatum
22.09.2018
Verlag
Springer Japan
Erschienen in
Journal of Gastroenterology / Ausgabe 1/2019
Print ISSN: 0944-1174
Elektronische ISSN: 1435-5922
DOI
https://doi.org/10.1007/s00535-018-1512-9

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