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Calcified Tissue International

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01.03.2015 | Review

Prospect for Pharmacological Therapies to Treat Skeletal Muscle Dysfunction

verfasst von: Matthew N. Meriggioli, Ronenn Roubenoff

Erschienen in: Calcified Tissue International | Ausgabe 3/2015

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Abstract

Skeletal muscle weakness is a leading cause of mobility disability in the elderly (sarcopenia), as a complication of acute or chronic illness (cachexia), and due to inherited or acquired muscle diseases (muscular dystrophies, myositides, etc.). As of now, there are no approved drugs that can reliably increase muscle strength and function. However, with our understanding of the regulation of myocyte signaling and homeostasis evolving rapidly, experimental treatments are now entering the clinic. We review the current status of clinical research in pharmacological therapies for muscle disorders.

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Titel: Prospect for Pharmacological Therapies to Treat Skeletal Muscle Dysfunction
verfasst von: Matthew N. Meriggioli
Ronenn Roubenoff
Publikationsdatum: 01.03.2015
Verlag: Springer US
Erschienen in: Calcified Tissue International / Ausgabe 3/2015
Print ISSN: 0171-967X
Elektronische ISSN: 1432-0827
DOI: https://doi.org/10.1007/s00223-014-9926-8

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