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Heart Failure Reviews

Erschienen in:

01.12.2007

Protection of the abnormal heart

verfasst von: Constantinos Pantos, Iordanis Mourouzis, Dennis V. Cokkinos

Erschienen in: Heart Failure Reviews | Ausgabe 3-4/2007

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Abstract

Myocardial ischemia and reperfusion injury have been extensively investigated in the laboratory mainly in healthy tissues. However, in clinical settings, ischemic heart disease coexists with certain illnesses, which could potentially influence the response of the myocardium to ischemia and reperfusion. Recent research has revealed that the abnormal heart may not be always vulnerable to ischemic injury. Furthermore, the effect of powerful means of protection, such as ischemic preconditioning, may not be in operation under certain pathological conditions. With this evidence in mind, the present review will focus on the response of the abnormal heart to ischemia and reperfusion, the possible underlying mechanisms, and potential cardioprotective strategies.

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Titel: Protection of the abnormal heart
verfasst von: Constantinos Pantos
Iordanis Mourouzis
Dennis V. Cokkinos
Publikationsdatum: 01.12.2007
Verlag: Kluwer Academic Publishers-Plenum Publishers
Erschienen in: Heart Failure Reviews / Ausgabe 3-4/2007
Print ISSN: 1382-4147
Elektronische ISSN: 1573-7322
DOI: https://doi.org/10.1007/s10741-007-9036-z

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