Skip to main content
Erschienen in: MUSCULOSKELETAL SURGERY 2/2021

01.02.2020 | Original Article

Proximal humeral fracture in patients with high Charlson comorbidity index: mortality rate according to treatment choice

verfasst von: Ana Belén Fernández-Cortiñas, Jesús Vidal Campos, Fernando Marco Martínez

Erschienen in: MUSCULOSKELETAL SURGERY | Ausgabe 2/2021

Einloggen, um Zugang zu erhalten

Abstract

Background

The purpose of this study was to evaluate the relevance of a commonly used morbidity prognostic tool, the Charlson comorbidity index (CCI), in determining the survival rate of patients with isolated proximal humeral fractures (PHFs) and to determine the impact of surgical treatment according to previous comorbidities (measured with CCI).

Materials and methods

All patients who were treated for a single PHF in our institution for 29 consecutive months were included in this retrospective study, with a minimum follow-up of 24 months (mean 52.8 months). Two groups were established according to the type of treatment received (surgical versus non-surgical). Preinjury comorbidities were identified, and the age-adapted CCI was calculated. All complications and mortality rates were prospectively recorded over the complete follow-up period.

Results

Patients with elevated preinjury comorbidities (CCI > 5) demonstrated a significant increase in mortality (HR = 4.64) compared to those with CCI ≤ 5. In addition, patients with high comorbidities (CCI > 5) who underwent surgical treatment demonstrated a statistically significant increase in mortality (HR = 6.92) compared to patients with similarly high comorbidities (CCI > 5) who underwent non-surgical treatment.

Conclusions

Patients with high preinjury comorbidities (CCI > 5) experienced an increased mortality risk if they underwent surgical treatment for isolated PHFs. The use of a morbidity prognostic tool, such as the CCI, can help predict the outcome (particularly mortality) in these patients and may aid in making decisions in terms of operative versus non-operative treatment to minimize patient mortality.

Level of evidence

Level III; Retrospective Comparative Study; Treatment Study.
Literatur
1.
Zurück zum Zitat Court-Brown CM, Garg A, McQueen MM (2001) The epidemiology of proximal humeral fractures. Acta Orthop Scand 72:365–371CrossRef Court-Brown CM, Garg A, McQueen MM (2001) The epidemiology of proximal humeral fractures. Acta Orthop Scand 72:365–371CrossRef
2.
Zurück zum Zitat Karl JW, Olson PR, Rosenwasser MP (2015) The epidemiology of upper extremity fractures in the United States, 2009. J Orthop Trauma 29:e242–e244CrossRef Karl JW, Olson PR, Rosenwasser MP (2015) The epidemiology of upper extremity fractures in the United States, 2009. J Orthop Trauma 29:e242–e244CrossRef
3.
Zurück zum Zitat Launonen AP, Lepola V, Saranko A, Flinkkila T, Laitinen M, Mattila VM (2015) Epidemiology of proximal humerus fractures. Arch Osteoporos 10:209CrossRef Launonen AP, Lepola V, Saranko A, Flinkkila T, Laitinen M, Mattila VM (2015) Epidemiology of proximal humerus fractures. Arch Osteoporos 10:209CrossRef
4.
Zurück zum Zitat Reyes C, Estrada P, Nogues X, Orozco P, Cooper C, Diez-Perez A, Formiga F, Gonzalez-Macias J, Prieto-Alhambra D (2014) The impact of common co-morbidities (as measured using the Charlson index) on hip fracture risk in elderly men: a population-based cohort study. Osteoporos Int 25:1751–1758CrossRef Reyes C, Estrada P, Nogues X, Orozco P, Cooper C, Diez-Perez A, Formiga F, Gonzalez-Macias J, Prieto-Alhambra D (2014) The impact of common co-morbidities (as measured using the Charlson index) on hip fracture risk in elderly men: a population-based cohort study. Osteoporos Int 25:1751–1758CrossRef
5.
Zurück zum Zitat LaMartina J, Christmas KN, Simon P, Streit JJ, Allert JW, Clark J, Otto RJ, Abdelfattah A, Mighell MA, Frankle MA (2018) Difficulty in decision making in the treatment of displaced proximal humerus fractures: the effect of uncertainty on surgical outcomes. J Shoulder Elbow Surg 27:470–477CrossRef LaMartina J, Christmas KN, Simon P, Streit JJ, Allert JW, Clark J, Otto RJ, Abdelfattah A, Mighell MA, Frankle MA (2018) Difficulty in decision making in the treatment of displaced proximal humerus fractures: the effect of uncertainty on surgical outcomes. J Shoulder Elbow Surg 27:470–477CrossRef
6.
Zurück zum Zitat Hasty EK, Jernigan EW 3rd, Soo A, Varkey DT, Kamath GV (2017) Trends in surgical management and costs for operative treatment of proximal humerus fractures in the elderly. Orthopedics 40:e641–e647CrossRef Hasty EK, Jernigan EW 3rd, Soo A, Varkey DT, Kamath GV (2017) Trends in surgical management and costs for operative treatment of proximal humerus fractures in the elderly. Orthopedics 40:e641–e647CrossRef
7.
Zurück zum Zitat Khatib O, Onyekwelu I, Zuckerman JD (2014) The incidence of proximal humeral fractures in New York state from 1990 through 2010 with an emphasis on operative management in patients aged 65 years or older. J Shoulder Elbow Surg 23:1356–1362CrossRef Khatib O, Onyekwelu I, Zuckerman JD (2014) The incidence of proximal humeral fractures in New York state from 1990 through 2010 with an emphasis on operative management in patients aged 65 years or older. J Shoulder Elbow Surg 23:1356–1362CrossRef
8.
Zurück zum Zitat Maravic M, Briot K, Roux C, Maravic M, Briot K, Roux C, Collège Français des Médecins Rhumatologues (CFMR) (2014) Burden of proximal humerus fractures in the French National Hospital Database. Orthop Traumatol Surg Res 100(8):931–934CrossRef Maravic M, Briot K, Roux C, Maravic M, Briot K, Roux C, Collège Français des Médecins Rhumatologues (CFMR) (2014) Burden of proximal humerus fractures in the French National Hospital Database. Orthop Traumatol Surg Res 100(8):931–934CrossRef
9.
Zurück zum Zitat Anakwenze OA, Zoller S, Ahmad CS, Levine WN (2014) Reverse shoulder arthroplasty for acute proximal humerus fractures: a systematic review. J Shoulder Elbow Surg 23:e73–e80CrossRef Anakwenze OA, Zoller S, Ahmad CS, Levine WN (2014) Reverse shoulder arthroplasty for acute proximal humerus fractures: a systematic review. J Shoulder Elbow Surg 23:e73–e80CrossRef
10.
Zurück zum Zitat Jost B, Spross C, Grehn H, Gerber C (2013) Locking plate fixation of fractures of the proximal humerus: analysis of complications, revision strategies and outcome. J Shoulder Elbow Surg 22:542–549CrossRef Jost B, Spross C, Grehn H, Gerber C (2013) Locking plate fixation of fractures of the proximal humerus: analysis of complications, revision strategies and outcome. J Shoulder Elbow Surg 22:542–549CrossRef
11.
Zurück zum Zitat Bell JE, Leung BC, Spratt KF, Koval KJ, Weinstein JD, Goodman DC, Tosteson AN (2011) Trends and variation in incidence, surgical treatment, and repeat surgery of proximal humeral fractures in the elderly. J Bone Joint Surg Am 93:121–131CrossRef Bell JE, Leung BC, Spratt KF, Koval KJ, Weinstein JD, Goodman DC, Tosteson AN (2011) Trends and variation in incidence, surgical treatment, and repeat surgery of proximal humeral fractures in the elderly. J Bone Joint Surg Am 93:121–131CrossRef
12.
Zurück zum Zitat Johnell O, Kanis JA, Oden A, Sernbo I, Redlund-Johnell I, Petterson C, De Laet C, Jonsson B (2004) Mortality after osteoporotic fractures. Osteoporos Int 15:38–42CrossRef Johnell O, Kanis JA, Oden A, Sernbo I, Redlund-Johnell I, Petterson C, De Laet C, Jonsson B (2004) Mortality after osteoporotic fractures. Osteoporos Int 15:38–42CrossRef
13.
Zurück zum Zitat Charlson ME, Pompei P, Ales KL, MacKenzie CR (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40:373–383CrossRef Charlson ME, Pompei P, Ales KL, MacKenzie CR (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40:373–383CrossRef
14.
Zurück zum Zitat Voskuijl T, Hageman M, Ring D (2014) Higher Charlson comorbidity index scores are associated with readmission after orthopaedic surgery. Clin Orthop Relat Res 472:1638–1644CrossRef Voskuijl T, Hageman M, Ring D (2014) Higher Charlson comorbidity index scores are associated with readmission after orthopaedic surgery. Clin Orthop Relat Res 472:1638–1644CrossRef
15.
Zurück zum Zitat Fernandez-Cortiñas AB, Vidal CJ, Paredes-Carnero X, Marco F (2019) Is the Charlson comorbidity index a good predictor of mortality and adverse effects in proximal humerus fractures? Orthop Traumatol Surg Res 105(2):301–305CrossRef Fernandez-Cortiñas AB, Vidal CJ, Paredes-Carnero X, Marco F (2019) Is the Charlson comorbidity index a good predictor of mortality and adverse effects in proximal humerus fractures? Orthop Traumatol Surg Res 105(2):301–305CrossRef
16.
Zurück zum Zitat Neer CS (2006) Displaced proximal humeral fractures: part I. Classification and evaluation. 1970. Clin Orthop Relat Res 442:77–82CrossRef Neer CS (2006) Displaced proximal humeral fractures: part I. Classification and evaluation. 1970. Clin Orthop Relat Res 442:77–82CrossRef
17.
Zurück zum Zitat Clavert P, Adam P, Bevort A, Bonnomet F, Kempf JF (2010) Pitfalls and complications with locking plate for proximal humerus fracture. J Shoulder Elbow Surg 19:489–494CrossRef Clavert P, Adam P, Bevort A, Bonnomet F, Kempf JF (2010) Pitfalls and complications with locking plate for proximal humerus fracture. J Shoulder Elbow Surg 19:489–494CrossRef
18.
Zurück zum Zitat Handoll HH, Brorson S (2015) Interventions for treating proximal humeral fractures in adults. Cochrane Database Syst Rev CD000434 Handoll HH, Brorson S (2015) Interventions for treating proximal humeral fractures in adults. Cochrane Database Syst Rev CD000434
19.
Zurück zum Zitat Rangan A, Handoll H, Brealey S, Jefferson L, Keding A, Martin BC, Goodchild L, Chuang LH, Hewitt C, Torgerson (2015) Surgical vs nonsurgical treatment of adults with displaced fractures of the proximal humerus: the PROFHER randomized clinical trial. JAMA 313:1037–1047CrossRef Rangan A, Handoll H, Brealey S, Jefferson L, Keding A, Martin BC, Goodchild L, Chuang LH, Hewitt C, Torgerson (2015) Surgical vs nonsurgical treatment of adults with displaced fractures of the proximal humerus: the PROFHER randomized clinical trial. JAMA 313:1037–1047CrossRef
20.
Zurück zum Zitat Roberson TA, Granade CM, Hunt Q, Griscom JT, Adams KJ, Momaya AM, Kwapisz A, Kissenberth MJ, Tolan SJ, Hawkins RJ, Tokish JM (2017) Nonoperative management versus reverse shoulder arthroplasty for treatment of 3- and 4-part proximal humeral fractures in older adults. J Shoulder Elbow Surg 26:1017–1022CrossRef Roberson TA, Granade CM, Hunt Q, Griscom JT, Adams KJ, Momaya AM, Kwapisz A, Kissenberth MJ, Tolan SJ, Hawkins RJ, Tokish JM (2017) Nonoperative management versus reverse shoulder arthroplasty for treatment of 3- and 4-part proximal humeral fractures in older adults. J Shoulder Elbow Surg 26:1017–1022CrossRef
21.
Zurück zum Zitat Court-Brown CM, Cattermole H, McQueen MM (2002) Impacted valgus fractures (B1.1) of the proximal humerus. The results of non-operative treatment. J Bone Joint Surg Br 84:504–508CrossRef Court-Brown CM, Cattermole H, McQueen MM (2002) Impacted valgus fractures (B1.1) of the proximal humerus. The results of non-operative treatment. J Bone Joint Surg Br 84:504–508CrossRef
22.
Zurück zum Zitat Foruria AM, de Gracia MM, Larson DR, Munuera L, Sanchez-Sotelo J (2011) The pattern of the fracture and displacement of the fragments predict the outcome in proximal humeral fractures. J Bone Joint Surg Br 93:378–386CrossRef Foruria AM, de Gracia MM, Larson DR, Munuera L, Sanchez-Sotelo J (2011) The pattern of the fracture and displacement of the fragments predict the outcome in proximal humeral fractures. J Bone Joint Surg Br 93:378–386CrossRef
23.
Zurück zum Zitat Olerud P, Ahrengart L, Ponzer S, Saving J, Tidermark (2011) Hemiarthroplasty versus nonoperative treatment of displaced 4-part proximal humeral fractures in elderly patients: a randomized controlled trial. J Shoulder Elbow Surg 20:1025–1033CrossRef Olerud P, Ahrengart L, Ponzer S, Saving J, Tidermark (2011) Hemiarthroplasty versus nonoperative treatment of displaced 4-part proximal humeral fractures in elderly patients: a randomized controlled trial. J Shoulder Elbow Surg 20:1025–1033CrossRef
24.
Zurück zum Zitat Shukla DR, McAnany S, Kim J, Overley S, Parsons BO (2016) Hemiarthroplasty versus reverse shoulder arthroplasty for treatment of proximal humeral fractures: a meta-analysis. J Shoulder Elbow Surg 25:330–340CrossRef Shukla DR, McAnany S, Kim J, Overley S, Parsons BO (2016) Hemiarthroplasty versus reverse shoulder arthroplasty for treatment of proximal humeral fractures: a meta-analysis. J Shoulder Elbow Surg 25:330–340CrossRef
25.
Zurück zum Zitat Neuhaus V, Bot AG, Swellengrebel CH, Jain NB, Warner JJ, Ring DC (2014) Treatment choice affects inpatient adverse events and mortality in older aged inpatients with an isolated fracture of the proximal humerus. J Shoulder Elbow Surg 23:800–806CrossRef Neuhaus V, Bot AG, Swellengrebel CH, Jain NB, Warner JJ, Ring DC (2014) Treatment choice affects inpatient adverse events and mortality in older aged inpatients with an isolated fracture of the proximal humerus. J Shoulder Elbow Surg 23:800–806CrossRef
26.
Zurück zum Zitat Amundsen A, Rasmussen JV, Olsen BS, Brorson S (2016) Mortality after shoulder arthroplasty: 30-day, 90-day, and 1-year mortality after shoulder replacement–5853 primary operations reported to the Danish Shoulder Arthroplasty Registry. J Shoulder Elbow Surg 25:756–762CrossRef Amundsen A, Rasmussen JV, Olsen BS, Brorson S (2016) Mortality after shoulder arthroplasty: 30-day, 90-day, and 1-year mortality after shoulder replacement–5853 primary operations reported to the Danish Shoulder Arthroplasty Registry. J Shoulder Elbow Surg 25:756–762CrossRef
27.
Zurück zum Zitat Inacio MC, Dillon MT, Miric A, Anthony F, Navarro RA, Paxton EW (2014) Mortality after shoulder arthroplasty. J Arthroplasty 29:1823–1826CrossRef Inacio MC, Dillon MT, Miric A, Anthony F, Navarro RA, Paxton EW (2014) Mortality after shoulder arthroplasty. J Arthroplasty 29:1823–1826CrossRef
28.
Zurück zum Zitat Beks RB, Ochen Y, Frima H, Smeeing DPJ, van der Meijden O, Timmers TK, van der Velde D, van Heijl M, Leenen LPH, Groenwold RHH, Houwert RM (2018) Operative versus nonoperative treatment of proximal humeral fractures: a systematic review, meta-analysis, and comparison of observational studies and randomized controlled trials. J Shoulder Elbow Surg 27:1526–1534CrossRef Beks RB, Ochen Y, Frima H, Smeeing DPJ, van der Meijden O, Timmers TK, van der Velde D, van Heijl M, Leenen LPH, Groenwold RHH, Houwert RM (2018) Operative versus nonoperative treatment of proximal humeral fractures: a systematic review, meta-analysis, and comparison of observational studies and randomized controlled trials. J Shoulder Elbow Surg 27:1526–1534CrossRef
29.
Zurück zum Zitat Launonen AP, Lepola V, Flinkkila T, Laitinen M, Paavola M, Malmivaara A (2015) Treatment of proximal humerus fractures in the elderly: a systemic review of 409 patients. Acta Orthop 86:280–285CrossRef Launonen AP, Lepola V, Flinkkila T, Laitinen M, Paavola M, Malmivaara A (2015) Treatment of proximal humerus fractures in the elderly: a systemic review of 409 patients. Acta Orthop 86:280–285CrossRef
30.
Zurück zum Zitat Neuhaus V, Swellengrebel CH, Bossen JK, Ring D (2013) What are the factors influencing outcome among patients admitted to a hospital with a proximal humeral fracture? Clin Orthop Relat Res 471:1698–1706CrossRef Neuhaus V, Swellengrebel CH, Bossen JK, Ring D (2013) What are the factors influencing outcome among patients admitted to a hospital with a proximal humeral fracture? Clin Orthop Relat Res 471:1698–1706CrossRef
Metadaten
Titel
Proximal humeral fracture in patients with high Charlson comorbidity index: mortality rate according to treatment choice
verfasst von
Ana Belén Fernández-Cortiñas
Jesús Vidal Campos
Fernando Marco Martínez
Publikationsdatum
01.02.2020
Verlag
Springer Milan
Erschienen in
MUSCULOSKELETAL SURGERY / Ausgabe 2/2021
Print ISSN: 2035-5106
Elektronische ISSN: 2035-5114
DOI
https://doi.org/10.1007/s12306-020-00642-2

Weitere Artikel der Ausgabe 2/2021

MUSCULOSKELETAL SURGERY 2/2021 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Arthroskopie kann Knieprothese nicht hinauszögern

25.04.2024 Gonarthrose Nachrichten

Ein arthroskopischer Eingriff bei Kniearthrose macht im Hinblick darauf, ob und wann ein Gelenkersatz fällig wird, offenbar keinen Unterschied.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Ärztliche Empathie hilft gegen Rückenschmerzen

23.04.2024 Leitsymptom Rückenschmerzen Nachrichten

Personen mit chronischen Rückenschmerzen, die von einfühlsamen Ärzten und Ärztinnen betreut werden, berichten über weniger Beschwerden und eine bessere Lebensqualität.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.