Erschienen in:
01.04.2017 | Cardiac Magnetic Resonance (E Nagel and V Puntmann, Section Editors)
Quantitative Tissue Characterization in Pediatric Cardiology
verfasst von:
Heiner Latus, Inga Voges
Erschienen in:
Current Cardiovascular Imaging Reports
|
Ausgabe 4/2017
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Abstract
Purpose of Review
This review discusses the cardiovascular magnetic resonance (CMR) myocardial tissue characterization techniques and its applications with a focus on pediatric patients. Delayed enhancement CMR (DE-CMR) is well established to detect focal myocardial fibrosis in the clinical setting but has its limitation in detecting diffuse myocardial disease. Newer mapping techniques allow exact assessment of myocardial relaxation times and their changes in various cardiac pathologies.
Recent Findings
T1 mapping gives new insights in diffuse myocardial disease in pediatric patients with tetralogy of Fallot. T2 mapping seems to be superior to other CMR parameters for identifying myocarditis. Changes in myocardial T2* in thalassemia major can be detected in childhood suggesting that myocardial damage occurs early in life.
Summary
Advanced CMR mapping techniques underlie a rapid development and enable a noninvasive characterization of the myocardium. Although data for young patients are limited, mapping techniques have the potential to become key imaging tools in pediatric patients.