Skip to main content
Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy 3/2017

14.10.2015 | Knee

Radiological outcomes in a randomized trial comparing opening wedge and closing wedge techniques of high tibial osteotomy

verfasst von: Tor Kjetil Nerhus, Arne Ekeland, Geir Solberg, Einar Andreas Sivertsen, Jan Erik Madsen, Stig Heir

Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy | Ausgabe 3/2017

Einloggen, um Zugang zu erhalten

Abstract

Purpose

The aim of the present study was to examine changes in radiological variables in a prospective randomized study comparing opening wedge (OW) and closing wedge (CW) techniques of high tibial osteotomy (HTO). Our hypothesis was that there would be no differences in joint line angles or correction accuracy between the two groups, that patellar height would increase after CW HTO and decrease after OW HTO, and that leg length and posterior tibial slope would decrease after CW HTO and increase after OW HTO.

Methods

Radiological data were collected from 70 patients participating in an ongoing prospective randomized clinical trial comparing OW and CW HTOs. Digital standing hip–knee–ankle (HKA) radiographs as well as lateral radiographs in 30° of flexion were obtained preoperatively and at 6 months for each patient. Joint line angles, HKA angle, leg length, Insall–Salvati index, Miura–Kawamura index and posterior tibial slope were measured using medical planning software. The complete preoperative radiological examinations of the first 50 patients were used in a study of intra- and inter-rater reliability of the measurements.

Results

The mean posterior slope was reduced by 2.5° in CW HTO, whereas it remained unchanged in OW HTO (p < 0.001). Mean leg length decreased 5.7 mm in CW HTO and increased 3.1 mm in OW HTO (p < 0.001). Changes in joint line angles, patellar height indexes and the correction accuracy showed no significant differences comparing the two techniques. Frontal plane reliability measurement intra- and inter-rater intraclass correlation coefficient (ICC) varied from 0.81 to 0.99. Sagittal plane intra- and inter-rater ICC varied from 0.60 to 0.87. Posterior tibial slope intra- and inter-rater ICC showed the lowest values (0.70 and 0.60, respectively) corresponding to a smallest real difference of 4.5° and 5.5°, respectively.

Conclusions

Posterior tibial slope and leg length changes were significantly different in CW compared to OW HTOs. We recommend that possible alterations in tibial slope and leg length are considered when the technique of HTO is to be chosen. Landmark-based medical planning software shows good reliability and can be used in preoperative planning and postoperative evaluations of HTOs.

Level of evidence

I.
Literatur
1.
Zurück zum Zitat Amzallag J, Pujol N, Maqdes A, Beaufils P, Judet T, Catonne Y (2013) Patellar height modification after high tibial osteotomy by either medial opening-wedge or lateral closing-wedge osteotomies. Knee Surg Sports Traumatol Arthrosc 21:255–259CrossRefPubMed Amzallag J, Pujol N, Maqdes A, Beaufils P, Judet T, Catonne Y (2013) Patellar height modification after high tibial osteotomy by either medial opening-wedge or lateral closing-wedge osteotomies. Knee Surg Sports Traumatol Arthrosc 21:255–259CrossRefPubMed
2.
Zurück zum Zitat Babis GC, An K-N, Chao EYS, Larson DR, Rand JA, Sim FH (2008) Upper tibia osteotomy: long term results—realignment analysis using OASIS computer software. J Orthop Sci Springer 13:328–334CrossRef Babis GC, An K-N, Chao EYS, Larson DR, Rand JA, Sim FH (2008) Upper tibia osteotomy: long term results—realignment analysis using OASIS computer software. J Orthop Sci Springer 13:328–334CrossRef
3.
Zurück zum Zitat Babis GC, An K-N, Chao EYS, Rand JA, Sim FH (2002) Double level osteotomy of the knee: a method to retain joint-line obliquity. Clinical results. J Bone Joint Surg Am 84-A:1380–1388CrossRefPubMed Babis GC, An K-N, Chao EYS, Rand JA, Sim FH (2002) Double level osteotomy of the knee: a method to retain joint-line obliquity. Clinical results. J Bone Joint Surg Am 84-A:1380–1388CrossRefPubMed
4.
Zurück zum Zitat Bae DK, Song SJ, Kim HJ, Seo JW (2013) Change in limb length after high tibial osteotomy using computer-assisted surgery: a comparative study of closed- and open-wedge osteotomies. Knee Surg Sports Traumatol Arthrosc 21:120–126CrossRefPubMed Bae DK, Song SJ, Kim HJ, Seo JW (2013) Change in limb length after high tibial osteotomy using computer-assisted surgery: a comparative study of closed- and open-wedge osteotomies. Knee Surg Sports Traumatol Arthrosc 21:120–126CrossRefPubMed
5.
Zurück zum Zitat Bito H, Takeuchi R, Kumagai K, Aratake M, Saito I, Hayashi R, Sasaki Y, Saito T (2010) Opening wedge high tibial osteotomy affects both the lateral patellar tilt and patellar height. Knee Surg Sports Traumatol Arthrosc 18:955–960CrossRefPubMed Bito H, Takeuchi R, Kumagai K, Aratake M, Saito I, Hayashi R, Sasaki Y, Saito T (2010) Opening wedge high tibial osteotomy affects both the lateral patellar tilt and patellar height. Knee Surg Sports Traumatol Arthrosc 18:955–960CrossRefPubMed
6.
Zurück zum Zitat Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307–310CrossRefPubMed Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307–310CrossRefPubMed
7.
Zurück zum Zitat Brouwer GM, van Tol AW, Bergink AP, Belo JN, Bernsen RMD, Reijman M, Pols HAP, Bierma-Zeinstra SMA (2007) Association between valgus and varus alignment and the development and progression of radiographic osteoarthritis of the knee. Arthritis Rheum 56:1204–1211CrossRefPubMed Brouwer GM, van Tol AW, Bergink AP, Belo JN, Bernsen RMD, Reijman M, Pols HAP, Bierma-Zeinstra SMA (2007) Association between valgus and varus alignment and the development and progression of radiographic osteoarthritis of the knee. Arthritis Rheum 56:1204–1211CrossRefPubMed
8.
Zurück zum Zitat Brouwer RW, Bierma-Zeinstra SMA, van Koeveringe AJ, Verhaar JAN (2005) Patellar height and the inclination of the tibial plateau after high tibial osteotomy. The open versus the closed-wedge technique. J Bone Joint Surg Br 87:1227–1232CrossRefPubMed Brouwer RW, Bierma-Zeinstra SMA, van Koeveringe AJ, Verhaar JAN (2005) Patellar height and the inclination of the tibial plateau after high tibial osteotomy. The open versus the closed-wedge technique. J Bone Joint Surg Br 87:1227–1232CrossRefPubMed
9.
Zurück zum Zitat Brouwer RW, Bierma-Zeinstra SMA, van Raaij TM, Verhaar JAN (2006) Osteotomy for medial compartment arthritis of the knee using a closing wedge or an opening wedge controlled by a Puddu plate. A one-year randomised, controlled study. J Bone Joint Surg Br 88:1454–1459CrossRefPubMed Brouwer RW, Bierma-Zeinstra SMA, van Raaij TM, Verhaar JAN (2006) Osteotomy for medial compartment arthritis of the knee using a closing wedge or an opening wedge controlled by a Puddu plate. A one-year randomised, controlled study. J Bone Joint Surg Br 88:1454–1459CrossRefPubMed
10.
Zurück zum Zitat Chae DJ, Shetty GM, Lee DB, Choi HW, Han SB, Nha KW (2008) Tibial slope and patellar height after opening wedge high tibia osteotomy using autologous tricortical iliac bone graft. Knee 15:128–133CrossRefPubMed Chae DJ, Shetty GM, Lee DB, Choi HW, Han SB, Nha KW (2008) Tibial slope and patellar height after opening wedge high tibia osteotomy using autologous tricortical iliac bone graft. Knee 15:128–133CrossRefPubMed
11.
Zurück zum Zitat Coventry MB (1987) Proximal tibial varus osteotomy for osteoarthritis of the lateral compartment of the knee. J Bone Joint Surg Am 69:32–38CrossRefPubMed Coventry MB (1987) Proximal tibial varus osteotomy for osteoarthritis of the lateral compartment of the knee. J Bone Joint Surg Am 69:32–38CrossRefPubMed
12.
Zurück zum Zitat Coventry MB, Ilstrup DM, Wallrichs SL (1993) Proximal tibial osteotomy. A critical long-term study of eighty-seven cases. J Bone Joint Surg Am 75:196–201CrossRefPubMed Coventry MB, Ilstrup DM, Wallrichs SL (1993) Proximal tibial osteotomy. A critical long-term study of eighty-seven cases. J Bone Joint Surg Am 75:196–201CrossRefPubMed
13.
Zurück zum Zitat Ducat A, Sariali E, Lebel B, Mertl P, Hernigou P, Flecher X, Zayni R, Bonnin M, Jalil R, Amzallag J, Rosset P, Servien E, Gaudot F, Judet T, Catonne Y (2012) Posterior tibial slope changes after opening- and closing-wedge high tibial osteotomy: a comparative prospective multicenter study. Orthop Traumatol Surg Res 98:68–74CrossRefPubMed Ducat A, Sariali E, Lebel B, Mertl P, Hernigou P, Flecher X, Zayni R, Bonnin M, Jalil R, Amzallag J, Rosset P, Servien E, Gaudot F, Judet T, Catonne Y (2012) Posterior tibial slope changes after opening- and closing-wedge high tibial osteotomy: a comparative prospective multicenter study. Orthop Traumatol Surg Res 98:68–74CrossRefPubMed
14.
Zurück zum Zitat Dugdale TW, Noyes FR, Styer D (1992) Preoperative planning for high tibial osteotomy. The effect of lateral tibiofemoral separation and tibiofemoral length. Clin Orthop Relat Res 274:248–264 Dugdale TW, Noyes FR, Styer D (1992) Preoperative planning for high tibial osteotomy. The effect of lateral tibiofemoral separation and tibiofemoral length. Clin Orthop Relat Res 274:248–264
15.
Zurück zum Zitat Duivenvoorden T, Brouwer RW, Baan A, Bos PK, Reijman M, Bierma-Zeinstra SMA, Verhaar JAN (2014) Comparison of closing-wedge and opening-wedge high tibial osteotomy for medial compartment osteoarthritis of the knee: a randomized controlled trial with a six-year follow-up. J Bone Joint Surg Am 96:1425–1432CrossRefPubMed Duivenvoorden T, Brouwer RW, Baan A, Bos PK, Reijman M, Bierma-Zeinstra SMA, Verhaar JAN (2014) Comparison of closing-wedge and opening-wedge high tibial osteotomy for medial compartment osteoarthritis of the knee: a randomized controlled trial with a six-year follow-up. J Bone Joint Surg Am 96:1425–1432CrossRefPubMed
16.
Zurück zum Zitat El-Azab H, Glabgly P, Paul J, Imhoff AB, Hinterwimmer S (2010) Patellar height and posterior tibial slope after open- and closed-wedge high tibial osteotomy: a radiological study on 100 patients. Am J Sports Med 38:323–329CrossRefPubMed El-Azab H, Glabgly P, Paul J, Imhoff AB, Hinterwimmer S (2010) Patellar height and posterior tibial slope after open- and closed-wedge high tibial osteotomy: a radiological study on 100 patients. Am J Sports Med 38:323–329CrossRefPubMed
17.
Zurück zum Zitat Gaasbeek R, Welsing R, Barink M, Verdonschot N, van Kampen A (2007) The influence of open and closed high tibial osteotomy on dynamic patellar tracking: a biomechanical study. Knee Surg Sports Traumatol Arthrosc 15:978–984CrossRefPubMed Gaasbeek R, Welsing R, Barink M, Verdonschot N, van Kampen A (2007) The influence of open and closed high tibial osteotomy on dynamic patellar tracking: a biomechanical study. Knee Surg Sports Traumatol Arthrosc 15:978–984CrossRefPubMed
18.
Zurück zum Zitat Gaasbeek RDA, Nicolaas L, Rijnberg WJ, van Loon CJM, van Kampen A (2010) Correction accuracy and collateral laxity in open versus closed wedge high tibial osteotomy. A one-year randomised controlled study. Int Orthop 34:201–207CrossRefPubMed Gaasbeek RDA, Nicolaas L, Rijnberg WJ, van Loon CJM, van Kampen A (2010) Correction accuracy and collateral laxity in open versus closed wedge high tibial osteotomy. A one-year randomised controlled study. Int Orthop 34:201–207CrossRefPubMed
20.
Zurück zum Zitat Hankemeier S, Mommsen P, Krettek C, Jagodzinski M, Brand J, Meyer C, Meller R (2010) Accuracy of high tibial osteotomy: comparison between open- and closed-wedge technique. Knee Surg Sports Traumatol Arthrosc 18:1328–1333CrossRefPubMed Hankemeier S, Mommsen P, Krettek C, Jagodzinski M, Brand J, Meyer C, Meller R (2010) Accuracy of high tibial osteotomy: comparison between open- and closed-wedge technique. Knee Surg Sports Traumatol Arthrosc 18:1328–1333CrossRefPubMed
21.
Zurück zum Zitat Hinterwimmer S, Beitzel K, Paul J, Kirchhoff C, Sauerschnig M, von Eisenhart-Rothe R, Imhoff AB (2011) Control of posterior tibial slope and patellar height in open-wedge valgus high tibial osteotomy. Am J Sports Med 39:851–856CrossRefPubMed Hinterwimmer S, Beitzel K, Paul J, Kirchhoff C, Sauerschnig M, von Eisenhart-Rothe R, Imhoff AB (2011) Control of posterior tibial slope and patellar height in open-wedge valgus high tibial osteotomy. Am J Sports Med 39:851–856CrossRefPubMed
22.
Zurück zum Zitat Hoell S, Suttmoeller J, Stoll V, Fuchs S, Gosheger G (2005) The high tibial osteotomy, open versus closed wedge, a comparison of methods in 108 patients. Arch Orthop Trauma Surg 125:638–643CrossRefPubMed Hoell S, Suttmoeller J, Stoll V, Fuchs S, Gosheger G (2005) The high tibial osteotomy, open versus closed wedge, a comparison of methods in 108 patients. Arch Orthop Trauma Surg 125:638–643CrossRefPubMed
23.
Zurück zum Zitat Insall J, Salvati E (1971) Patella position in the normal knee joint. Radiology 101:101–104CrossRefPubMed Insall J, Salvati E (1971) Patella position in the normal knee joint. Radiology 101:101–104CrossRefPubMed
24.
Zurück zum Zitat Kaper BP, Bourne RB, Rorabeck CH, MacDonald SJ (2001) Patellar infera after high tibial osteotomy. J Arthroplasty 16:168–173CrossRefPubMed Kaper BP, Bourne RB, Rorabeck CH, MacDonald SJ (2001) Patellar infera after high tibial osteotomy. J Arthroplasty 16:168–173CrossRefPubMed
25.
Zurück zum Zitat Kesmezacar H, Erginer R, Ogut T, Seyahi A, Babacan M, Tenekecioglu Y (2005) Evaluation of patellar height and measurement methods after valgus high tibial osteotomy. Knee Surg Sports Traumatol Arthrosc 13:539–544CrossRefPubMed Kesmezacar H, Erginer R, Ogut T, Seyahi A, Babacan M, Tenekecioglu Y (2005) Evaluation of patellar height and measurement methods after valgus high tibial osteotomy. Knee Surg Sports Traumatol Arthrosc 13:539–544CrossRefPubMed
26.
Zurück zum Zitat Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159–174CrossRefPubMed Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159–174CrossRefPubMed
27.
Zurück zum Zitat LaPrade RF, Oro FB, Ziegler CG, Wijdicks CA, Walsh MP (2010) Patellar height and tibial slope after opening-wedge proximal tibial osteotomy: a prospective study. Am J Sports Med 38:160–170CrossRefPubMed LaPrade RF, Oro FB, Ziegler CG, Wijdicks CA, Walsh MP (2010) Patellar height and tibial slope after opening-wedge proximal tibial osteotomy: a prospective study. Am J Sports Med 38:160–170CrossRefPubMed
28.
Zurück zum Zitat Luites JWH, Brinkman J-M, Wymenga AB, van Heerwaarden RJ (2009) Fixation stability of opening- versus closing-wedge high tibial osteotomy: a randomised clinical trial using radiostereometry. J Bone Joint Surg Br 91:1459–1465CrossRefPubMed Luites JWH, Brinkman J-M, Wymenga AB, van Heerwaarden RJ (2009) Fixation stability of opening- versus closing-wedge high tibial osteotomy: a randomised clinical trial using radiostereometry. J Bone Joint Surg Br 91:1459–1465CrossRefPubMed
29.
Zurück zum Zitat Magnussen RA, Lustig S, Demey G, Neyret P, Servien E (2011) The effect of medial opening and lateral closing high tibial osteotomy on leg length. Am J Sports Med 39:1900–1905CrossRefPubMed Magnussen RA, Lustig S, Demey G, Neyret P, Servien E (2011) The effect of medial opening and lateral closing high tibial osteotomy on leg length. Am J Sports Med 39:1900–1905CrossRefPubMed
30.
Zurück zum Zitat Miura H, Kawamura H, Nagamine R, Urabe K, Iwamoto Y (1997) Is patellar height really lower after high tibial osteotomy? Fukuoka Igaku Zasshi 88:261–266PubMed Miura H, Kawamura H, Nagamine R, Urabe K, Iwamoto Y (1997) Is patellar height really lower after high tibial osteotomy? Fukuoka Igaku Zasshi 88:261–266PubMed
31.
32.
Zurück zum Zitat Roos EM, Lohmander LS (2003) The Knee injury and Osteoarthritis Outcome Score (KOOS): from joint injury to osteoarthritis. Health Qual Life Outcomes 1:64CrossRefPubMedPubMedCentral Roos EM, Lohmander LS (2003) The Knee injury and Osteoarthritis Outcome Score (KOOS): from joint injury to osteoarthritis. Health Qual Life Outcomes 1:64CrossRefPubMedPubMedCentral
33.
Zurück zum Zitat Savarese E, Bisicchia S, Romeo R, Amendola A (2011) Role of high tibial osteotomy in chronic injuries of posterior cruciate ligament and posterolateral corner. J Orthop Traumatol 12:1–17CrossRefPubMed Savarese E, Bisicchia S, Romeo R, Amendola A (2011) Role of high tibial osteotomy in chronic injuries of posterior cruciate ligament and posterolateral corner. J Orthop Traumatol 12:1–17CrossRefPubMed
34.
Zurück zum Zitat Schiedel F, Probst A, Buller TC, Rödl R (2009) The postoperative patella height: a comparison of additive and subtractive high tibial osteotomy in correcting the genu varum. Arch Orthop Trauma Surg 129:1271–1277CrossRefPubMed Schiedel F, Probst A, Buller TC, Rödl R (2009) The postoperative patella height: a comparison of additive and subtractive high tibial osteotomy in correcting the genu varum. Arch Orthop Trauma Surg 129:1271–1277CrossRefPubMed
35.
Zurück zum Zitat Schröter S, Ihle C, Mueller J, Lobenhoffer P, Stöckle U, van Heerwaarden R (2013) Digital planning of high tibial osteotomy. Interrater reliability by using two different software. Knee Surg Sports Traumatol Arthrosc 21:189–196CrossRefPubMed Schröter S, Ihle C, Mueller J, Lobenhoffer P, Stöckle U, van Heerwaarden R (2013) Digital planning of high tibial osteotomy. Interrater reliability by using two different software. Knee Surg Sports Traumatol Arthrosc 21:189–196CrossRefPubMed
36.
Zurück zum Zitat Schulz KF, Grimes DA (2002) Generation of allocation sequences in randomised trials: chance, not choice. Lancet 359:515–519CrossRefPubMed Schulz KF, Grimes DA (2002) Generation of allocation sequences in randomised trials: chance, not choice. Lancet 359:515–519CrossRefPubMed
37.
Zurück zum Zitat Shelburne KB, Kim H-J, Sterett WI, Pandy MG (2011) Effect of posterior tibial slope on knee biomechanics during functional activity. J Orthop Res 29:223–231CrossRefPubMed Shelburne KB, Kim H-J, Sterett WI, Pandy MG (2011) Effect of posterior tibial slope on knee biomechanics during functional activity. J Orthop Res 29:223–231CrossRefPubMed
38.
Zurück zum Zitat Shoji H, Insall J (1973) High tibial osteotomy for osteoarthritis of the knee with valgus deformity. J Bone Joint Surg Am 55:963–973CrossRefPubMed Shoji H, Insall J (1973) High tibial osteotomy for osteoarthritis of the knee with valgus deformity. J Bone Joint Surg Am 55:963–973CrossRefPubMed
39.
Zurück zum Zitat Sled EA, Sheehy LM, Felson DT, Costigan PA, Lam M, Cooke TDV (2011) Reliability of lower limb alignment measures using an established landmark-based method with a customized computer software program. Rheumatol Int 31:71–77CrossRefPubMed Sled EA, Sheehy LM, Felson DT, Costigan PA, Lam M, Cooke TDV (2011) Reliability of lower limb alignment measures using an established landmark-based method with a customized computer software program. Rheumatol Int 31:71–77CrossRefPubMed
40.
Zurück zum Zitat Smith JO, Wilson AJ, Thomas NP (2013) Osteotomy around the knee: evolution, principles and results. Knee Surg Sports Traumatol Arthrosc 21:3–22CrossRefPubMed Smith JO, Wilson AJ, Thomas NP (2013) Osteotomy around the knee: evolution, principles and results. Knee Surg Sports Traumatol Arthrosc 21:3–22CrossRefPubMed
41.
Zurück zum Zitat Spahn G (2004) Complications in high tibial (medial opening wedge) osteotomy. Arch Orthop Trauma Surg 124:649–653CrossRefPubMed Spahn G (2004) Complications in high tibial (medial opening wedge) osteotomy. Arch Orthop Trauma Surg 124:649–653CrossRefPubMed
42.
Zurück zum Zitat Webb JM, Salmon LJ, Leclerc E, Pinczewski LA, Roe JP (2013) Posterior tibial slope and further anterior cruciate ligament injuries in the anterior cruciate ligament-reconstructed patient. Am J Sports Med 41:2800–2804CrossRefPubMed Webb JM, Salmon LJ, Leclerc E, Pinczewski LA, Roe JP (2013) Posterior tibial slope and further anterior cruciate ligament injuries in the anterior cruciate ligament-reconstructed patient. Am J Sports Med 41:2800–2804CrossRefPubMed
Metadaten
Titel
Radiological outcomes in a randomized trial comparing opening wedge and closing wedge techniques of high tibial osteotomy
verfasst von
Tor Kjetil Nerhus
Arne Ekeland
Geir Solberg
Einar Andreas Sivertsen
Jan Erik Madsen
Stig Heir
Publikationsdatum
14.10.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
Knee Surgery, Sports Traumatology, Arthroscopy / Ausgabe 3/2017
Print ISSN: 0942-2056
Elektronische ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-015-3817-z

Weitere Artikel der Ausgabe 3/2017

Knee Surgery, Sports Traumatology, Arthroscopy 3/2017 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Arthroskopie kann Knieprothese nicht hinauszögern

25.04.2024 Gonarthrose Nachrichten

Ein arthroskopischer Eingriff bei Kniearthrose macht im Hinblick darauf, ob und wann ein Gelenkersatz fällig wird, offenbar keinen Unterschied.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Ärztliche Empathie hilft gegen Rückenschmerzen

23.04.2024 Leitsymptom Rückenschmerzen Nachrichten

Personen mit chronischen Rückenschmerzen, die von einfühlsamen Ärzten und Ärztinnen betreut werden, berichten über weniger Beschwerden und eine bessere Lebensqualität.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.