Skip to main content


Radiotherapy for patients with cardiovascular implantable electronic devices: an 11-year experience

Journal of Interventional Cardiac Electrophysiology
Cynthia Yeung, Bachar Hazim, Debra Campbell, Jim Gooding, Shirley XL Li, Ho Kit Tam, Wilma M. Hopman, Sanoj Chacko, Damian P. Redfearn, Christopher Simpson, Hoshiar Abdollah, Adrian Baranchuk
Wichtige Hinweise

Electronic supplementary material

The online version of this article (https://​doi.​org/​10.​1007/​s10840-018-0506-0) contains supplementary material, which is available to authorized users.
What’s New?
● Although radiotherapy (RT)-induced device malfunctions are rare, there are no universal evidence-based guidelines for the management of patients with cardiovascular implantable electronic devices (CIEDs) undergoing RT, and considerable variation exists in clinical practice.
● There has been no published literature detailing a formal workflow for the interdisciplinary management of patients with CIEDs requiring RT.
● This manuscript will describe a standardized protocol for the communication and collaboration between the radiation oncology and cardiology departments for the purposes of (i) ensuring patients with CIEDs are safely treated when they require RT, and (ii) minimizing the risk of CIED failure when RT is given; and evaluate the data from the 11-year experience regarding the recommendations and device malfunctions.



As cardiovascular implantable electronic devices (CIEDs) are increasingly indicated in older patients, and the burden of cancer is rising with the aging population, the management of patients with CIEDs who require radiotherapy (RT) is a timely concern. The objective of the study was to evaluate the management of, and malfunctions in, patients with CIEDs undergoing RT.


A retrospective study of patients with CIEDs receiving RT at Kingston Health Sciences Center from March 2007–April 2018 was conducted. Data on demographics, RT, devices, and management were compared for the primary outcome of device malfunction.


Of the 189 patients with CIEDs receiving a total of 297 courses of RT, 4 patients (2.1%) experienced device malfunctions. Higher beam energy was associated with a malfunction (p < 0.05). Patients with malfunctions received a lower dose of radiation per fraction (267 ± 93 cGy vs. 477 ± 282 cGy; p < 0.05) and were significantly younger (71.4 ± 2.2 years vs. 77.8 ± 9.8 years; p < 0.01) compared to patients without malfunctions.


RT-induced device malfunctions are rare, but given the potential complications, a better understanding of the potential predictors of malfunction and the development of evidence-based guidelines will help optimize patient safety.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

e.Med Interdisziplinär

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf Zusätzlich können Sie eine Zeitschrift Ihrer Wahl in gedruckter Form beziehen – ohne Aufpreis.

Weitere Produktempfehlungen anzeigen
ESM 1 (PDF 575 kb)
Über diesen Artikel
  1. Sie können e.Med Innere Medizin 14 Tage kostenlos testen (keine Print-Zeitschrift enthalten). Der Test läuft automatisch und formlos aus. Es kann nur einmal getestet werden.

Neu im Fachgebiet Kardiologie

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Kardiologie und bleiben Sie gut informiert – ganz bequem per eMail.