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Arthritis Research & Therapy

Erschienen in:

01.08.2010 | Review

Rationale of using different biological therapies in rheumatoid arthritis

verfasst von: Matthias Geyer, Ulf Müller-Ladner

Erschienen in: Arthritis Research & Therapy | Ausgabe 4/2010

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Abstract

Due to ongoing developments of novel agents in the field of biological pharmacotherapy, there are now more arrows available in clinicians' quivers for the treatment of rheumatic conditions. As a consequence, however, clear treatment strategies have to be defined in order to guarantee a qualitatively high and individually stage-adapted, state-of-the-art regimen for affected patients. This review summarizes recent evidence regarding the rationale of using different biological therapies to treat rheumatoid arthritis, the most common inflammatory joint disorder after activated osteoarthritis, and draws an actual picture of a possible standardized therapeutic algorithm without claiming exclusive appropriateness.

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Titel: Rationale of using different biological therapies in rheumatoid arthritis
verfasst von: Matthias Geyer
Ulf Müller-Ladner
Publikationsdatum: 01.08.2010
Verlag: BioMed Central
Erschienen in: Arthritis Research & Therapy / Ausgabe 4/2010
Elektronische ISSN: 1478-6362
DOI: https://doi.org/10.1186/ar3102

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Alterations in the self-renewal and differentiation ability of bone marrow mesenchymal stem cells in a mouse model of rheumatoid arthritis

Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis