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Erschienen in: Current Infectious Disease Reports 5/2011

01.10.2011

Recent Advances in the Treatment of Necrotizing Fasciitis

verfasst von: Marina S. Morgan

Erschienen in: Current Infectious Disease Reports | Ausgabe 5/2011

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Abstract

With four types of necrotizing fasciitis (NF) now recognized, the diagnosis and management of NF becomes more challenging as physicians face more unusual pathogenic and atypical presentations. With few published guidelines and little evidence base to justify therapies, much of the literature is pragmatic or provides limited evidence with small underpowered studies and disparate case reports.
Literatur
1.
Zurück zum Zitat Meleney FL. Haemolytic streptococcal gangrene. Importance of early diagnosis and early operation. JAMA. 1929;92:2009–12. Meleney FL. Haemolytic streptococcal gangrene. Importance of early diagnosis and early operation. JAMA. 1929;92:2009–12.
2.
Zurück zum Zitat Fournier J-A. Gangrène foudroyante de la verge. La Semaine Medicale. 1883;3:345–8. Fournier J-A. Gangrène foudroyante de la verge. La Semaine Medicale. 1883;3:345–8.
3.
Zurück zum Zitat Giuliano A, Lewis Jr F, Hadley K, et al. Bacteriology of necrotizing fasciitis. Am J Surg. 1977;134:52–7.PubMedCrossRef Giuliano A, Lewis Jr F, Hadley K, et al. Bacteriology of necrotizing fasciitis. Am J Surg. 1977;134:52–7.PubMedCrossRef
4.
Zurück zum Zitat •• Morgan MS. Diagnosis and management of necrotising fasciitis: a multiparametric approach. J Hosp Infect. 2010;75:249–57. The most recent overview, and a new classification of necrotizing fasciitis. PubMedCrossRef •• Morgan MS. Diagnosis and management of necrotising fasciitis: a multiparametric approach. J Hosp Infect. 2010;75:249–57. The most recent overview, and a new classification of necrotizing fasciitis. PubMedCrossRef
5.
Zurück zum Zitat Nuwayhid ZB, Aronoff DM, Mulla ZD. Blunt trauma as a risk factor for group A streptococcal necrotizing fasciitis. Ann Epidemiol. 2007;17:878–81.PubMedCrossRef Nuwayhid ZB, Aronoff DM, Mulla ZD. Blunt trauma as a risk factor for group A streptococcal necrotizing fasciitis. Ann Epidemiol. 2007;17:878–81.PubMedCrossRef
6.
Zurück zum Zitat Yamashiro E, Asato Y, Taira K, et al. Necrotizing fasciitis caused by Streptococcus pneumoniae. J Dermatol. 2009;36:298–305.PubMedCrossRef Yamashiro E, Asato Y, Taira K, et al. Necrotizing fasciitis caused by Streptococcus pneumoniae. J Dermatol. 2009;36:298–305.PubMedCrossRef
7.
Zurück zum Zitat Lee YT, Chou TD, Peng MY, et al. Rapidly progressive necrotizing fasciitis caused by Staphylococcus aureus. J Microbiol Immunol Infect. 2005;38:361–4.PubMed Lee YT, Chou TD, Peng MY, et al. Rapidly progressive necrotizing fasciitis caused by Staphylococcus aureus. J Microbiol Immunol Infect. 2005;38:361–4.PubMed
8.
Zurück zum Zitat Regev A, Weinberger M, Fishman M, et al. Necrotizing fasciitis caused by Staphylococcus aureus. Eur J Clin Microbiol Infect Dis. 1998;17:101–3.PubMed Regev A, Weinberger M, Fishman M, et al. Necrotizing fasciitis caused by Staphylococcus aureus. Eur J Clin Microbiol Infect Dis. 1998;17:101–3.PubMed
9.
Zurück zum Zitat Romano R, Lu D, Holtom P. Outbreak of community-acquired methicillin-resistant Staphylococcus aureus skin infections among a collegiate football team. J Athl Train. 2006;41:141–5.PubMed Romano R, Lu D, Holtom P. Outbreak of community-acquired methicillin-resistant Staphylococcus aureus skin infections among a collegiate football team. J Athl Train. 2006;41:141–5.PubMed
10.
Zurück zum Zitat Alvarez CA, Barientes OJ, Leal AL, et al. Community-associated Methicillin-resistant Staphylococcus aureus, Colombia. Emerg Infect Dis. 2006;12:2001–2. Alvarez CA, Barientes OJ, Leal AL, et al. Community-associated Methicillin-resistant Staphylococcus aureus, Colombia. Emerg Infect Dis. 2006;12:2001–2.
11.
Zurück zum Zitat Lee TC, Carrick M, Scott BG, et al. The incidence and clinical characteristics of methicillin-resistant Staphylococcus aureus necrotizing fasciitis in a large urban hospital American. J Surg. 2007;194:809–13.CrossRef Lee TC, Carrick M, Scott BG, et al. The incidence and clinical characteristics of methicillin-resistant Staphylococcus aureus necrotizing fasciitis in a large urban hospital American. J Surg. 2007;194:809–13.CrossRef
12.
Zurück zum Zitat Wong CH, Tan SH, Kurup A, et al. Recurrent necrotizing fasciitis caused by methicillin-resistant Staphylococcus aureus. Eur J Clin Microbiol Infect Dis. 2004;23:909–11.PubMed Wong CH, Tan SH, Kurup A, et al. Recurrent necrotizing fasciitis caused by methicillin-resistant Staphylococcus aureus. Eur J Clin Microbiol Infect Dis. 2004;23:909–11.PubMed
13.
Zurück zum Zitat Bodemer C, Panhans A, Chretien-Marquet B, et al. Staphylococcal necrotizing fasciitis in the mammary region in childhood: a report of five cases. J Pediatr. 1997;131:466–9.PubMedCrossRef Bodemer C, Panhans A, Chretien-Marquet B, et al. Staphylococcal necrotizing fasciitis in the mammary region in childhood: a report of five cases. J Pediatr. 1997;131:466–9.PubMedCrossRef
14.
Zurück zum Zitat Peker E, Kirimi E, Tuncer O, et al. Necrotizing fasciitis caused by Staphylococcus epidermidis in a neonate with extremely low birthweight. J Dermatol. 2010;37:671–3.PubMedCrossRef Peker E, Kirimi E, Tuncer O, et al. Necrotizing fasciitis caused by Staphylococcus epidermidis in a neonate with extremely low birthweight. J Dermatol. 2010;37:671–3.PubMedCrossRef
15.
Zurück zum Zitat Carmin M, Kalorin CM, Tobin EH. Community associated methicillin resistant Staphylococcus Aureus causing Fournier’s gangrene and genital infections. 2007;177:967–71. Carmin M, Kalorin CM, Tobin EH. Community associated methicillin resistant Staphylococcus Aureus causing Fournier’s gangrene and genital infections. 2007;177:967–71.
16.
Zurück zum Zitat Young LM, Price CS. Community-acquired methicillin-resistant Staphylococcus aureus emerging as an important cause of necrotizing fasciitis. Surg Infect. 2008;9:469–74.CrossRef Young LM, Price CS. Community-acquired methicillin-resistant Staphylococcus aureus emerging as an important cause of necrotizing fasciitis. Surg Infect. 2008;9:469–74.CrossRef
17.
Zurück zum Zitat Ohlsen RJ, Burns KM, Chen L, et al. Severe necrotizing fasciitis in a human immunodeficiency virus-positive patient caused by methicillin-resistant Staphylococcus aureus. J Clin Micro. 2008;46:1144–7.CrossRef Ohlsen RJ, Burns KM, Chen L, et al. Severe necrotizing fasciitis in a human immunodeficiency virus-positive patient caused by methicillin-resistant Staphylococcus aureus. J Clin Micro. 2008;46:1144–7.CrossRef
18.
Zurück zum Zitat Dehority W, Wang E, Vernon PS, et al. Community-associated methicillin-resistant Staphylococcus aureus necrotizing fasciitis in a neonate. Pediatr Infect Dis J. 2006;25:1080–1.PubMedCrossRef Dehority W, Wang E, Vernon PS, et al. Community-associated methicillin-resistant Staphylococcus aureus necrotizing fasciitis in a neonate. Pediatr Infect Dis J. 2006;25:1080–1.PubMedCrossRef
19.
Zurück zum Zitat Hayani KC, Mathew R, Oyedele T, Hulten KG. Neonatal necrotizing fasciitis due to community-acquired methicillin resistant Staphylococcus aureus. Pediatr Infect Dis J. 2008;27:480–81.PubMedCrossRef Hayani KC, Mathew R, Oyedele T, Hulten KG. Neonatal necrotizing fasciitis due to community-acquired methicillin resistant Staphylococcus aureus. Pediatr Infect Dis J. 2008;27:480–81.PubMedCrossRef
20.
Zurück zum Zitat Orii KO, Iwao Y, Higuchi W, et al. Molecular characterization of methicillin resistant Staphylococcus aureus from a fatal case of necrotizing fasciitis in an extremely low-birth-weight infant. Clin Microbiol Infect. 2010;16:289–92.PubMedCrossRef Orii KO, Iwao Y, Higuchi W, et al. Molecular characterization of methicillin resistant Staphylococcus aureus from a fatal case of necrotizing fasciitis in an extremely low-birth-weight infant. Clin Microbiol Infect. 2010;16:289–92.PubMedCrossRef
21.
Zurück zum Zitat Miller LG, Perdreau-Remington F, Rieg G, et al. Necrotizing fasciitis caused by community-associated methicillin-resistant Staphylococcus aureus in Los Angeles. N Engl J Med. 2005;352:1445–53.PubMedCrossRef Miller LG, Perdreau-Remington F, Rieg G, et al. Necrotizing fasciitis caused by community-associated methicillin-resistant Staphylococcus aureus in Los Angeles. N Engl J Med. 2005;352:1445–53.PubMedCrossRef
22.
Zurück zum Zitat • Salcido R: Necrotizing fasciitis: reviewing the causes and treatment strategies. Adv Skin Wound Care 2007; 20:288–93. Excellent overview- covers most aspects of diagnosis and therapy. PubMedCrossRef • Salcido R: Necrotizing fasciitis: reviewing the causes and treatment strategies. Adv Skin Wound Care 2007; 20:288–93. Excellent overview- covers most aspects of diagnosis and therapy. PubMedCrossRef
23.
Zurück zum Zitat •• Sarani B, Strong M, Pascual J et al. Necrotizing fasciitis: current concepts and review of the literature. J Am Coll Surg. 2009;208:279–88. Very comprehensive and thorough overview. Excellent photographs and tables, and easy to read. PubMedCrossRef •• Sarani B, Strong M, Pascual J et al. Necrotizing fasciitis: current concepts and review of the literature. J Am Coll Surg. 2009;208:279–88. Very comprehensive and thorough overview. Excellent photographs and tables, and easy to read. PubMedCrossRef
24.
Zurück zum Zitat Goodell KH, Jordan MR, Graham R, et al. Rapidly advancing necrotizing fasciitis caused by Photobacterium (Vibrio) damsela: a hyperaggressive variant. Crit Care Med. 2004;32:278–81.PubMedCrossRef Goodell KH, Jordan MR, Graham R, et al. Rapidly advancing necrotizing fasciitis caused by Photobacterium (Vibrio) damsela: a hyperaggressive variant. Crit Care Med. 2004;32:278–81.PubMedCrossRef
25.
Zurück zum Zitat Lee C-H, Wang C-C, Yue C-T Li J-Y WuY-K. Necrotising fasciitis caused by Vibrio vulnificus in a man with cirrhosis. Lancet Infect Dis. 2008;8:399.PubMedCrossRef Lee C-H, Wang C-C, Yue C-T Li J-Y WuY-K. Necrotising fasciitis caused by Vibrio vulnificus in a man with cirrhosis. Lancet Infect Dis. 2008;8:399.PubMedCrossRef
26.
Zurück zum Zitat Klontz KC, Lieb S, Schreiber M, et al. Syndromes of Vibrio vulnificus infections. Clinical and epidemiological features in Florida cases, 1981–1987. Ann Intern Med. 1988;109:318.PubMed Klontz KC, Lieb S, Schreiber M, et al. Syndromes of Vibrio vulnificus infections. Clinical and epidemiological features in Florida cases, 1981–1987. Ann Intern Med. 1988;109:318.PubMed
27.
28.
Zurück zum Zitat McLellan E, Suvarna K, Townsend R. Fatal necrotising fasciitis caused by Haemophilus influenzae serotype f. J Med Microbiol. 2008;57:249–51.PubMedCrossRef McLellan E, Suvarna K, Townsend R. Fatal necrotising fasciitis caused by Haemophilus influenzae serotype f. J Med Microbiol. 2008;57:249–51.PubMedCrossRef
29.
Zurück zum Zitat Saito T, Matsunaga H, Matsumura Y, et al. Necrotizing fasciitis caused by Haemophilus influenzae type b in an elderly patient. J Clin Microbiol. 2009;47:852–4.PubMedCrossRef Saito T, Matsunaga H, Matsumura Y, et al. Necrotizing fasciitis caused by Haemophilus influenzae type b in an elderly patient. J Clin Microbiol. 2009;47:852–4.PubMedCrossRef
30.
Zurück zum Zitat Wong CH, Kurup A, Wang YS, et al. Four cases of necrotizing fasciitis caused by Klebsiella species. Eur J Clin Microbiol Infect Dis. 2004;23:403–7.PubMedCrossRef Wong CH, Kurup A, Wang YS, et al. Four cases of necrotizing fasciitis caused by Klebsiella species. Eur J Clin Microbiol Infect Dis. 2004;23:403–7.PubMedCrossRef
31.
Zurück zum Zitat Monaghan SF, Anjaria D, Mohr A, et al. Necrotizing fasciitis and sepsis caused by Aeromonas hydrophila after crush injury of the lower extremity. Surg Infect. 2008;9:459–67.CrossRef Monaghan SF, Anjaria D, Mohr A, et al. Necrotizing fasciitis and sepsis caused by Aeromonas hydrophila after crush injury of the lower extremity. Surg Infect. 2008;9:459–67.CrossRef
32.
Zurück zum Zitat Cui H, Hao S, Arous E. A distinct cause of necrotizing fasciitis: Aeromonas veronii Biovar Sobria. Surg Infect. 2007;8:523–8.CrossRef Cui H, Hao S, Arous E. A distinct cause of necrotizing fasciitis: Aeromonas veronii Biovar Sobria. Surg Infect. 2007;8:523–8.CrossRef
33.
Zurück zum Zitat • Charnot-Katsikas A, Dorafshar AH, Aycock JK et al. Two cases of necrotizing fasciitis due to Acinetobacter baumannii. J Clin Microbiol. 2009;47:258–63. Worrying cases of multi-drug resistant NF superinfection in immunocompromised patient. • Charnot-Katsikas A, Dorafshar AH, Aycock JK et al. Two cases of necrotizing fasciitis due to Acinetobacter baumannii. J Clin Microbiol. 2009;47:258–63. Worrying cases of multi-drug resistant NF superinfection in immunocompromised patient.
34.
Zurück zum Zitat Cook DA, Heiner JP, Rao VK. Necrotizing candidal fasciitis following hip surgery. Orthopedics. 1990;13:768–70.PubMed Cook DA, Heiner JP, Rao VK. Necrotizing candidal fasciitis following hip surgery. Orthopedics. 1990;13:768–70.PubMed
35.
Zurück zum Zitat Shindo M, Yoshida Y, Adachi K, et al. Necrotizing soft-tissue infection caused by both Candida glabrata and Streptococcus agalactiae. Arch Dermatol. 2009;145:I96–97.CrossRef Shindo M, Yoshida Y, Adachi K, et al. Necrotizing soft-tissue infection caused by both Candida glabrata and Streptococcus agalactiae. Arch Dermatol. 2009;145:I96–97.CrossRef
36.
Zurück zum Zitat Jain D, Kumar Y, Vasishta RK, et al. Zygomycotic necrotizing fasciitis in immunocompetent patients: a series of 18 cases. Mod Pathol. 2006;19:1221–6.PubMedCrossRef Jain D, Kumar Y, Vasishta RK, et al. Zygomycotic necrotizing fasciitis in immunocompetent patients: a series of 18 cases. Mod Pathol. 2006;19:1221–6.PubMedCrossRef
37.
Zurück zum Zitat Aronoff DM, Bloch KC. Assessing the relationship between the use of NSAIDS and necrotizing fasciitis caused by group A streptococcus. Medicine. 2003;82:225–35.PubMed Aronoff DM, Bloch KC. Assessing the relationship between the use of NSAIDS and necrotizing fasciitis caused by group A streptococcus. Medicine. 2003;82:225–35.PubMed
38.
Zurück zum Zitat Wong CH, Khin LW, Heng KS. The laboratory risk indicator for necrotising fasciitis score: a tool for distinguishing necrotising fasciitis from other soft tissue infection. Crit Care Med. 2004;32:135–41.CrossRef Wong CH, Khin LW, Heng KS. The laboratory risk indicator for necrotising fasciitis score: a tool for distinguishing necrotising fasciitis from other soft tissue infection. Crit Care Med. 2004;32:135–41.CrossRef
39.
Zurück zum Zitat Su Y-C, Chen H-W, Hong Y-C, et al. Laboratory risk indicator for necrotizing fasciitis and the outcomes. ANZJ Surg. 2008;78:968–72.CrossRef Su Y-C, Chen H-W, Hong Y-C, et al. Laboratory risk indicator for necrotizing fasciitis and the outcomes. ANZJ Surg. 2008;78:968–72.CrossRef
40.
Zurück zum Zitat Macuha F, Ahn A, Graham R. Necrotizing fasciitis associated with acupuncture: a case report. J Hosp Med. 2010;10:565–6.CrossRef Macuha F, Ahn A, Graham R. Necrotizing fasciitis associated with acupuncture: a case report. J Hosp Med. 2010;10:565–6.CrossRef
41.
Zurück zum Zitat Barie PS. The laboratory risk indicator for necrotizing fasciitis (LRINEC) score: useful tool or paralysis by analysis? Crit Care Med. 2004;32:1618–9.PubMedCrossRef Barie PS. The laboratory risk indicator for necrotizing fasciitis (LRINEC) score: useful tool or paralysis by analysis? Crit Care Med. 2004;32:1618–9.PubMedCrossRef
42.
Zurück zum Zitat Wang T-W, Hung C-R. Role of tissue oxygen saturation monitoring in diagnosing necrotizing fasciitis of the lower limbs. Ann Emerg Med. 2004;44:222–8.PubMedCrossRef Wang T-W, Hung C-R. Role of tissue oxygen saturation monitoring in diagnosing necrotizing fasciitis of the lower limbs. Ann Emerg Med. 2004;44:222–8.PubMedCrossRef
43.
Zurück zum Zitat Zahar J-R Goveia J, Lesprit P, et al. Severe soft tissue infections of the extremities in patients admitted to an intensive care unit. CMI. 2004;11:79–82. Zahar J-R Goveia J, Lesprit P, et al. Severe soft tissue infections of the extremities in patients admitted to an intensive care unit. CMI. 2004;11:79–82.
44.
Zurück zum Zitat Darbar A, Harris IA, Gosbell IB. Necrotizing infection due to Bacillus cereus mimicking gas gangrene following penetrating trauma. J Orthop Trauma. 2005;19:353–5.PubMed Darbar A, Harris IA, Gosbell IB. Necrotizing infection due to Bacillus cereus mimicking gas gangrene following penetrating trauma. J Orthop Trauma. 2005;19:353–5.PubMed
45.
Zurück zum Zitat • Sada A, Misago N, Okawa T, et al. Necrotizing fasciitis and myonecrosis “synergistic necrotizing cellulitis” caused by Bacillus cereus J Dermatol. 2009;36:423–26. Case report with good X-rays and photographs of an infection that could easily be mistreated. PubMedCrossRef • Sada A, Misago N, Okawa T, et al. Necrotizing fasciitis and myonecrosis “synergistic necrotizing cellulitis” caused by Bacillus cereus J Dermatol. 2009;36:423–26. Case report with good X-rays and photographs of an infection that could easily be mistreated. PubMedCrossRef
46.
Zurück zum Zitat Stevens DL, Bisno AL, Chambers HF, et al. Practice guidelines for the management of skin and soft tissue infections. Clin Infect Dis. 2005;41:1373–406.PubMedCrossRef Stevens DL, Bisno AL, Chambers HF, et al. Practice guidelines for the management of skin and soft tissue infections. Clin Infect Dis. 2005;41:1373–406.PubMedCrossRef
48.
Zurück zum Zitat Tang WM, Ho PL, Fung KK, et al. Necrotizing fasciitis of a limb. J Bone Joint Surg [Br]. 2001;83-B:709–14.CrossRef Tang WM, Ho PL, Fung KK, et al. Necrotizing fasciitis of a limb. J Bone Joint Surg [Br]. 2001;83-B:709–14.CrossRef
49.
Zurück zum Zitat • Lehnhardt M, Homann H, Daigeler A, et al. Major and lethal complications of liposuction: a review of 72 cases in Germany between 1998 and 2002. Plast Reconstr Surg. 2008;121:396e–403e. Surgically orientated but very useful background for understanding of infections following plastic surgery procedures. PubMedCrossRef • Lehnhardt M, Homann H, Daigeler A, et al. Major and lethal complications of liposuction: a review of 72 cases in Germany between 1998 and 2002. Plast Reconstr Surg. 2008;121:396e–403e. Surgically orientated but very useful background for understanding of infections following plastic surgery procedures. PubMedCrossRef
50.
Zurück zum Zitat Andreasson TJ, Green SD, Childers BJ. Massive soft tissue injury: diagnosis and management of necrotising fasciitis and purpura fulminans. Plast Reconstr Surg. 2001;107:1025–34.CrossRef Andreasson TJ, Green SD, Childers BJ. Massive soft tissue injury: diagnosis and management of necrotising fasciitis and purpura fulminans. Plast Reconstr Surg. 2001;107:1025–34.CrossRef
51.
Zurück zum Zitat Eagle H. Experimental approach to the problem of treatment failures with penicillin. I. Group A streptococcal infection in mice. Am J Med. 1952;13:389–99.PubMedCrossRef Eagle H. Experimental approach to the problem of treatment failures with penicillin. I. Group A streptococcal infection in mice. Am J Med. 1952;13:389–99.PubMedCrossRef
52.
Zurück zum Zitat Stevens DL, Gibbons AE, Bergstrom R, et al. The Eagle effect revisited: efficacy of clindamycin, erythromycin and penicillin in the treatment of streptococcal myositis. J Infect Dis. 1988;158:23–8.PubMedCrossRef Stevens DL, Gibbons AE, Bergstrom R, et al. The Eagle effect revisited: efficacy of clindamycin, erythromycin and penicillin in the treatment of streptococcal myositis. J Infect Dis. 1988;158:23–8.PubMedCrossRef
53.
Zurück zum Zitat De Decker K, Van Poucke S, Wojciechowski M, et al. Successful use of posaconazole in a pediatric case of fungal necrotizing fasciitis. Pediatr Crit Care Med. 2006;7:482–5.PubMedCrossRef De Decker K, Van Poucke S, Wojciechowski M, et al. Successful use of posaconazole in a pediatric case of fungal necrotizing fasciitis. Pediatr Crit Care Med. 2006;7:482–5.PubMedCrossRef
54.
Zurück zum Zitat Stevens DL, Ma Y, McIndoo E, et al. Impact of antibiotics on expression of virulence-associated exotoxin genes in methicillin-sensitive and methicillin-resistant Staphylococcus aureus. J Infect Dis. 2007;195:202–11.PubMedCrossRef Stevens DL, Ma Y, McIndoo E, et al. Impact of antibiotics on expression of virulence-associated exotoxin genes in methicillin-sensitive and methicillin-resistant Staphylococcus aureus. J Infect Dis. 2007;195:202–11.PubMedCrossRef
55.
Zurück zum Zitat Bakleh M, Wold LE, Mandrekar JN, et al. Correlation of histopathological findings with clinical outcome in necrotizing fasciitis. Clin Infect Dis. 2005;40:410–4.PubMedCrossRef Bakleh M, Wold LE, Mandrekar JN, et al. Correlation of histopathological findings with clinical outcome in necrotizing fasciitis. Clin Infect Dis. 2005;40:410–4.PubMedCrossRef
56.
Zurück zum Zitat Mulla ZD, Leaverton PE, Wiersma ST. Invasive group A streptococcal infections in Florida. South Med J. 2003;968–73. Mulla ZD, Leaverton PE, Wiersma ST. Invasive group A streptococcal infections in Florida. South Med J. 2003;968–73.
57.
Zurück zum Zitat Zimbelman J, Palmer A, Todd J. Improved outcome of clindamycin compared with beta-lactam antibiotics treatment for invasive Streptococcus pyogenes infection. Paed Inf Dis J. 1999;12:1096–110.CrossRef Zimbelman J, Palmer A, Todd J. Improved outcome of clindamycin compared with beta-lactam antibiotics treatment for invasive Streptococcus pyogenes infection. Paed Inf Dis J. 1999;12:1096–110.CrossRef
58.
Zurück zum Zitat Panagaea S, Perry JD, Gould JK. Should clindamycin be used as treatment of patients with infections caused by erythromycin-resistant streptococci? J Antimicrob Chemother. 1999;44:581–2.CrossRef Panagaea S, Perry JD, Gould JK. Should clindamycin be used as treatment of patients with infections caused by erythromycin-resistant streptococci? J Antimicrob Chemother. 1999;44:581–2.CrossRef
59.
Zurück zum Zitat Diener BC. Avoidance of dominant hand amputation in a patient with uncontrolled diabetes. Adv Skin Wound Care. 2010;23:219–22.PubMedCrossRef Diener BC. Avoidance of dominant hand amputation in a patient with uncontrolled diabetes. Adv Skin Wound Care. 2010;23:219–22.PubMedCrossRef
60.
Zurück zum Zitat Lamothe F, D’Amico P, Ghosn P, et al. Clinical usefulness of human immunoglobulins in invasive group A streptococcus infections: a review. Clin Infect Dis. 1995;21:469–70.CrossRef Lamothe F, D’Amico P, Ghosn P, et al. Clinical usefulness of human immunoglobulins in invasive group A streptococcus infections: a review. Clin Infect Dis. 1995;21:469–70.CrossRef
61.
Zurück zum Zitat Korzets A, Ori Y, Zevin D, et al. Streptococcal bacteraemia and necrotizing fasciitis in a renal transplant patient; a case for intravenous immunoglobulin therapy. Nephrol Dial Transplant. 2002;17:150–2.PubMedCrossRef Korzets A, Ori Y, Zevin D, et al. Streptococcal bacteraemia and necrotizing fasciitis in a renal transplant patient; a case for intravenous immunoglobulin therapy. Nephrol Dial Transplant. 2002;17:150–2.PubMedCrossRef
62.
Zurück zum Zitat Yaghoubian A, de Virgilio C, Dauphine C, et al. Use of admission serum lactate and sodium levels to predict mortality in necrotizing soft tissue infection. Arch Surg. 2007;142:840–6.PubMedCrossRef Yaghoubian A, de Virgilio C, Dauphine C, et al. Use of admission serum lactate and sodium levels to predict mortality in necrotizing soft tissue infection. Arch Surg. 2007;142:840–6.PubMedCrossRef
63.
Zurück zum Zitat Cawley MJ, Briggs M, Haith LR, et al. Intravenous immunoglobulin as adjunctive treatment for Streptococcal toxic shock syndrome associated with necrotizing fasciitis: case report and review. Pharmacotherapy. 1999;19:1094–98.PubMedCrossRef Cawley MJ, Briggs M, Haith LR, et al. Intravenous immunoglobulin as adjunctive treatment for Streptococcal toxic shock syndrome associated with necrotizing fasciitis: case report and review. Pharmacotherapy. 1999;19:1094–98.PubMedCrossRef
64.
Zurück zum Zitat •• de Moya MA, del Carmen MG, Allain RM et al. Case 33–2009: a 35-year-old woman with fever, abdominal pain, and hypotension after cesarean section. N Engl J Med. 2009;361:1689–97. An instructive case of GASNF following caesarian and the complications and management problems. Good histological and clinical photographs. PubMedCrossRef •• de Moya MA, del Carmen MG, Allain RM et al. Case 33–2009: a 35-year-old woman with fever, abdominal pain, and hypotension after cesarean section. N Engl J Med. 2009;361:1689–97. An instructive case of GASNF following caesarian and the complications and management problems. Good histological and clinical photographs. PubMedCrossRef
65.
Zurück zum Zitat Kaul R, McGreer A, Low DE, et al. Population based surveillance for Group A streptococcal necrotizing fasciitis: clinical features, prognostic indicators, and microbiologic analysis of 77 cases. Am J Med. 1997;103:18–24.PubMedCrossRef Kaul R, McGreer A, Low DE, et al. Population based surveillance for Group A streptococcal necrotizing fasciitis: clinical features, prognostic indicators, and microbiologic analysis of 77 cases. Am J Med. 1997;103:18–24.PubMedCrossRef
66.
Zurück zum Zitat Mehta S, McGeer A, Low DE, et al. Morbidity and mortality of patients with invasive group A streptococcal infections admitted to the ICU. Chest. 2006;130:1679–86.PubMedCrossRef Mehta S, McGeer A, Low DE, et al. Morbidity and mortality of patients with invasive group A streptococcal infections admitted to the ICU. Chest. 2006;130:1679–86.PubMedCrossRef
67.
Zurück zum Zitat Alejandria MM, Lansang MAD, Dans LF, et al. Intravenous immunoglobulin for treating sepsis, severe sepsis and septic shock. Cochrane Database Syst Rev. 2002; Issue 1. Art. No.: CD001090. doi:10.1002/14651858.CD001090. Alejandria MM, Lansang MAD, Dans LF, et al. Intravenous immunoglobulin for treating sepsis, severe sepsis and septic shock. Cochrane Database Syst Rev. 2002; Issue 1. Art. No.: CD001090. doi:10.​1002/​14651858.​CD001090.
68.
Zurück zum Zitat Minodier P, Bidet P, Rallu F, et al. Clinical and microbiologic characteristics of group A streptococcal necrotising fasciitis in children. Ped Infect Dis J. 2009;28:541.CrossRef Minodier P, Bidet P, Rallu F, et al. Clinical and microbiologic characteristics of group A streptococcal necrotising fasciitis in children. Ped Infect Dis J. 2009;28:541.CrossRef
69.
Zurück zum Zitat Darenberg J, Ihendyane N, Sjölin J, et al. Intravenous immunoglobulin G therapy in streptococcal toxic shock syndrome: a European randomized, double-blind, placebo-controlled trial. Clin Infect Dis. 2003;37:333–40.PubMedCrossRef Darenberg J, Ihendyane N, Sjölin J, et al. Intravenous immunoglobulin G therapy in streptococcal toxic shock syndrome: a European randomized, double-blind, placebo-controlled trial. Clin Infect Dis. 2003;37:333–40.PubMedCrossRef
70.
Zurück zum Zitat Chapman SJR, Opdam H, Donato R, et al. Successful management of severe group A streptococcal soft tissue infections using an aggressive medical regimen including intravenous immunoglobulin together with a conservative surgical approach. Scand J Infect Dis. 2006;38:742–3.PubMedCrossRef Chapman SJR, Opdam H, Donato R, et al. Successful management of severe group A streptococcal soft tissue infections using an aggressive medical regimen including intravenous immunoglobulin together with a conservative surgical approach. Scand J Infect Dis. 2006;38:742–3.PubMedCrossRef
72.
Zurück zum Zitat Sellers BJ, Woods ML, Morris ASE, et al. Necrotizing Group A streptococcal infection associated with streptococcal toxic shock syndrome. Am J Surg. 1996;172:523–8.PubMedCrossRef Sellers BJ, Woods ML, Morris ASE, et al. Necrotizing Group A streptococcal infection associated with streptococcal toxic shock syndrome. Am J Surg. 1996;172:523–8.PubMedCrossRef
73.
Zurück zum Zitat Meredith FT, Fowler VG, Gautier M, et al. Bacillus cereus necrotizing cellulitis mimicking clostridial myonecrosis: case report and review of the literature. Scand J Infect. 1997;29:528–9.CrossRef Meredith FT, Fowler VG, Gautier M, et al. Bacillus cereus necrotizing cellulitis mimicking clostridial myonecrosis: case report and review of the literature. Scand J Infect. 1997;29:528–9.CrossRef
74.
Zurück zum Zitat Bilton BB, Zibarui GB, McMillan RW, et al. Aggressive surgical management of necrotising fasciitis serves to decrease mortality: a retrospective study. Amer Surg. 1998;64:397–401. Bilton BB, Zibarui GB, McMillan RW, et al. Aggressive surgical management of necrotising fasciitis serves to decrease mortality: a retrospective study. Amer Surg. 1998;64:397–401.
75.
Zurück zum Zitat Wakhlu A, Chaudhary A, Tandon RK, et al. Conservative management of necrotizing fasciitis in children. J Pediatr Surg. 2006;41:1144–8.PubMedCrossRef Wakhlu A, Chaudhary A, Tandon RK, et al. Conservative management of necrotizing fasciitis in children. J Pediatr Surg. 2006;41:1144–8.PubMedCrossRef
76.
Zurück zum Zitat Bingöl-Kologlu M, Yildiz RV, Alper B, et al. Necrotizing fasciitis in children: diagnostic and therapeutic aspects. J Pediatr Surg. 2007;42:1892–7.PubMedCrossRef Bingöl-Kologlu M, Yildiz RV, Alper B, et al. Necrotizing fasciitis in children: diagnostic and therapeutic aspects. J Pediatr Surg. 2007;42:1892–7.PubMedCrossRef
77.
Zurück zum Zitat Wong C-H, Yam AK-T, Tan A, et al. Approach to debridement in necrotizing fasciitis. Am J Surg. 2008;196:e19–24. A thorough surgical paper especially useful for microbiologists who are not regularly in theatre.PubMedCrossRef Wong C-H, Yam AK-T, Tan A, et al. Approach to debridement in necrotizing fasciitis. Am J Surg. 2008;196:e19–24. A thorough surgical paper especially useful for microbiologists who are not regularly in theatre.PubMedCrossRef
78.
Zurück zum Zitat Tahmaz L, Eedemir T, Kibar Y, et al. Fournier’s gangrene: report of thirty-three cases and a review of the literature. Int J Urol. 2006;13:960–7.PubMedCrossRef Tahmaz L, Eedemir T, Kibar Y, et al. Fournier’s gangrene: report of thirty-three cases and a review of the literature. Int J Urol. 2006;13:960–7.PubMedCrossRef
79.
Zurück zum Zitat Minhas KM. Pneumococcal purpura fulminans successfully treated with activated Protein C. [Report]. South Med J. 2008;101:1046–8.PubMedCrossRef Minhas KM. Pneumococcal purpura fulminans successfully treated with activated Protein C. [Report]. South Med J. 2008;101:1046–8.PubMedCrossRef
81.
Zurück zum Zitat Nagoba BS, Gandhi RC, Wadher BJ, et al. Citric acid treatment of necrotizing fasciitis: a report of two cases. Int Wound J. 2010;7:536–8.PubMedCrossRef Nagoba BS, Gandhi RC, Wadher BJ, et al. Citric acid treatment of necrotizing fasciitis: a report of two cases. Int Wound J. 2010;7:536–8.PubMedCrossRef
82.
Zurück zum Zitat Nagoba BS, Gandhi RC, Wadher BJ, et al. Microbiological, histopathological and clinical changes in chronic wounds after citric acid treatment. J Med Microbiol. 2008;57:681–2.PubMedCrossRef Nagoba BS, Gandhi RC, Wadher BJ, et al. Microbiological, histopathological and clinical changes in chronic wounds after citric acid treatment. J Med Microbiol. 2008;57:681–2.PubMedCrossRef
83.
Zurück zum Zitat • Sakata S, Das Gupta R, Leditschke JF et al. Extensive necrotising fasciitis in a 4-day-old neonate: a successful outcome from modern dressings, intensive care and early surgical intervention. Pediatr Surg Int. 2009;25:117–9.PubMedCrossRef • Sakata S, Das Gupta R, Leditschke JF et al. Extensive necrotising fasciitis in a 4-day-old neonate: a successful outcome from modern dressings, intensive care and early surgical intervention. Pediatr Surg Int. 2009;25:117–9.PubMedCrossRef
84.
Zurück zum Zitat Fitzgerald RH, Bharara M, Mills JL, et al. Use of a Nanoflex powder dressing for wound management following debridement for necrotising fasciitis in the diabetic foot. Int Wound J. 2009;6:133–9.PubMedCrossRef Fitzgerald RH, Bharara M, Mills JL, et al. Use of a Nanoflex powder dressing for wound management following debridement for necrotising fasciitis in the diabetic foot. Int Wound J. 2009;6:133–9.PubMedCrossRef
85.
Zurück zum Zitat •• Czymek, R, Schmidt A, Eckmann C et al. Fournier’s gangrene: vacuum-assisted closure versus conventional dressings. Am J Surg. 2009;197:168–76. Case series and excellent overview of history of FG, VAC device and surgery. Good photographs. PubMedCrossRef •• Czymek, R, Schmidt A, Eckmann C et al. Fournier’s gangrene: vacuum-assisted closure versus conventional dressings. Am J Surg. 2009;197:168–76. Case series and excellent overview of history of FG, VAC device and surgery. Good photographs. PubMedCrossRef
86.
Zurück zum Zitat Gorlek A, Firat C, Oztqrk AE, et al. Management of necrotizing fasciitis in diabetic patients. J Diabet Comp. 2007;21:265–71.CrossRef Gorlek A, Firat C, Oztqrk AE, et al. Management of necrotizing fasciitis in diabetic patients. J Diabet Comp. 2007;21:265–71.CrossRef
87.
Zurück zum Zitat Jallali N, Ithey S, Butler PE. Hyperbaric oxygen as adjuvant therapy in the management of necrotizing fasciitis. Am J Surg. 2005;189:462–6. Thorough and honest overview explaining mechanisms of HBO action, pros and cons of HBO and review of cases where HBO used.PubMedCrossRef Jallali N, Ithey S, Butler PE. Hyperbaric oxygen as adjuvant therapy in the management of necrotizing fasciitis. Am J Surg. 2005;189:462–6. Thorough and honest overview explaining mechanisms of HBO action, pros and cons of HBO and review of cases where HBO used.PubMedCrossRef
88.
Zurück zum Zitat Kakis A, Gibbs L, Equia J, et al. An outbreak of Group A streptococcal infection among health care workers. Clinic Inf Dis. 2002;35:1353–9.CrossRef Kakis A, Gibbs L, Equia J, et al. An outbreak of Group A streptococcal infection among health care workers. Clinic Inf Dis. 2002;35:1353–9.CrossRef
89.
Zurück zum Zitat • Sablier F, Slaouti T, Drèze P-A et al. Nosocomial transmission of necrotising fasciitis. Lancet. 2010;375:1052. Transmission after blade injury during surgery. PubMedCrossRef • Sablier F, Slaouti T, Drèze P-A et al. Nosocomial transmission of necrotising fasciitis. Lancet. 2010;375:1052. Transmission after blade injury during surgery. PubMedCrossRef
90.
Zurück zum Zitat Gamba M-A, Martinelli M, Schaad HJ, et al. Familial transmission of a serious disease –producing Group A streptococcus clone: case reports and review. Clin Infect Dis. 1997;24:1118–21.PubMedCrossRef Gamba M-A, Martinelli M, Schaad HJ, et al. Familial transmission of a serious disease –producing Group A streptococcus clone: case reports and review. Clin Infect Dis. 1997;24:1118–21.PubMedCrossRef
91.
Zurück zum Zitat Interim UK guidelines for management of close community contacts of invasive group A streptococcal disease. Comm Dis Pub Health. 2004;7:364–71. Interim UK guidelines for management of close community contacts of invasive group A streptococcal disease. Comm Dis Pub Health. 2004;7:364–71.
92.
Zurück zum Zitat Wong C-H, Song C, Ong Y-S et al. Abdominal wall necrotizing fasciitis: it is Still “Meleney’s minefield”. Plastic Reconstruct Surg. 2006;147–150e. Wong C-H, Song C, Ong Y-S et al. Abdominal wall necrotizing fasciitis: it is Still “Meleney’s minefield”. Plastic Reconstruct Surg. 2006;147–150e.
Metadaten
Titel
Recent Advances in the Treatment of Necrotizing Fasciitis
verfasst von
Marina S. Morgan
Publikationsdatum
01.10.2011
Verlag
Current Science Inc.
Erschienen in
Current Infectious Disease Reports / Ausgabe 5/2011
Print ISSN: 1523-3847
Elektronische ISSN: 1534-3146
DOI
https://doi.org/10.1007/s11908-011-0205-9

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