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Cardiovascular Toxicology

Erschienen in:

30.05.2016

Refractory Cardiogenic Shock During Tramadol Poisoning: A Case Report

verfasst von: Nicolas Belin, Anne-Laure Clairet, Sidney Chocron, Gilles Capellier, Gaël Piton

Erschienen in: Cardiovascular Toxicology | Ausgabe 2/2017

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Abstract

Tramadol is a weak opioid analgesic indicated for the treatment of moderate to severe pain. Tramadol intoxication can be lethal, and this drug is frequently involved in voluntary overdose. Classically, tramadol intoxication is associated with neurological and respiratory side effects. In contrast, cardiac effects are poorly documented in the literature. We report a case of severe tramadol intoxication, with plasma concentration 20 times the toxic threshold, complicated by refractory cardiogenic shock, successfully treated by extra corporeal life support (ECLS) with a favorable cardiac outcome and ECLS weaning at day 10. Seizure, clonus, and nonreactive mydriasis were present during 4 days, and complete awakening was delayed to day 15. Poisoning caused by high doses of tramadol can lead to refractory cardiogenic shock, and ECLS can be considered as effective rescue therapy in this context.

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Titel: Refractory Cardiogenic Shock During Tramadol Poisoning: A Case Report
verfasst von: Nicolas Belin
Anne-Laure Clairet
Sidney Chocron
Gilles Capellier
Gaël Piton
Publikationsdatum: 30.05.2016
Verlag: Springer US
Erschienen in: Cardiovascular Toxicology / Ausgabe 2/2017
Print ISSN: 1530-7905
Elektronische ISSN: 1559-0259
DOI: https://doi.org/10.1007/s12012-016-9373-z

Springer Medizin

Abstract

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