Acknowledgements
We gratefully thank all CENTER-TBI participants and investigators. We are immensely grateful to our patients for helping us in our efforts to improve care and outcomes after TBI.
The CENTER-TBI participants and investigators
Cecilia Åkerlund18, Krisztina Amrein19, Nada Andelic1,3, Lasse Andreassen20, Audny Anke21, Anna Antoni22, Gérard Audibert23, Philippe Azouvi14,15, Maria Luisa Azzolini24, Ronald Bartels25, Pál Barzó26, Romuald Beauvais27, Ronny Beer28, Bo-Michael Bellander29, Antonio Belli30, Habib Benali31, Maurizio Berardino32, Luigi Beretta24, Morten Blaabjerg33, Peter Bragge34, Alexandra Brazinova35, Vibeke Brinck36, Joanne Brooker37, Camilla Brorsson38, Andras Buki39, Monika Bullinger40, Manuel Cabeleira41, Alessio Caccioppola42, Emiliana Calappi 42, Maria Rosa Calvi24, Peter Cameron43, Guillermo Carbayo Lozano44, Marco Carbonara42, Simona Cavallo32, Giorgio Chevallard45, Arturo Chieregato45, Giuseppe Citerio46, 47, Hans Clusmann48, Mark Coburn49, Jonathan Coles50, Jamie D. Cooper52, Marta Correia52, Amra Čović2, Nicola Curry53, Endre Czeiter39, Marek Czosnyka41, Claire Dahyot-Fizelier54, Paul Dark55, Helen Dawes16,17, Véronique De Keyser56, Vincent Degos31, Francesco Della Corte57, Hugo den Boogert25, Bart Depreitere58, Đula Đilvesi 59, Abhishek Dixit60, Emma Donoghue37, Jens Dreier61, Guy-Loup Dulière62, Ari Ercole60, Patrick Esser17, Erzsébet Ezer63, Martin Fabricius64, Valery L. Feigin65, Kelly Foks66, Shirin Frisvold67, Alex Furmanov68, Pablo Gagliardo69, Damien Galanaud31, Dashiell Gantner43, Guoyi Gao70, Pradeep George71, Alexandre Ghuysen72, Lelde Giga73, Ben Glocker74, Jagoš Golubovic59, Pedro A. Gomez75, Johannes Gratz76, Benjamin Gravesteijn77, Francesca Grossi57, Russell L. Gruen78, Deepak Gupta79, Juanita A. Haagsma77, Iain Haitsma80, Raimund Helbok28, Eirik Helseth7,8, Lindsay Horton 81, Jilske Huijben77, Peter J. Hutchinson82, Bram Jacobs83, Stefan Jankowski84, Mike Jarrett36, Ji-yao Jiang71, Faye Johnson85, Kelly Jones65, Mladen Karan59, Angelos G. Kolias82, Erwin Kompanje86, Daniel Kondziella64, Evgenios Kornaropoulos60, Lars-Owe Koskinen87, Noémi Kovács88, Ana Kowark89, Alfonso Lagares75, Linda Lanyon71, Steven Laureys90, Fiona Lecky91, 92, Didier Ledoux90, Rolf Lefering93, Valerie Legrand94, Aurelie Lejeune95, Leon Levi96, Roger Lightfoot97, Hester Lingsma77, Andrew I.R. Maas56, Ana M. Castaño-León62, Marc Maegele98, Marek Majdan35, Alex Manara99, Geoffrey Manley100, Costanza Martino101, Hugues Maréchal62, Julia Mattern102, Catherine McMahon103, Béla Melegh104, David Menon60, Tomas Menovsky56, Ana Mikolic77, Benoit Misset90, Visakh Muraleedharan71, Lynnette Murray43, Ancuta Negru105, David Nelson18, Virginia Newcombe60, Daan Nieboer77, József Nyirádi19, Otesile Olubukola91, Matej Oresic106, Fabrizio Ortolano42, Aarno Palotie107, 108, 109, Paul M. Parizel110, Jean-François Payen111, Natascha Perera27, Vincent Perlbarg31, Paolo Persona112, Wilco Peul113, Anna Piippo-Karjalainen114, Matti Pirinen107, Dana Pisica77, Horia Ples105, Suzanne Polinder77, Inigo Pomposo44, Jussi P. Posti 12,13, Louis Puybasset115, Andreea Radoi 116, Arminas Ragauskas117, Rahul Raj114, Malinka Rambadagalla118, Isabel Retel Helmrich77, Jonathan Rhodes119, Sylvia Richardson120, Sophie Richter60, Samuli Ripatti107, Saulius Rocka117, Cecilie Roe1,3,8, Olav Roise121,122, Jonathan Rosand123, Jeffrey V. Rosenfeld124, Christina Rosenlund125, Guy Rosenthal68, Rolf Rossaint89, Sandra Rossi112, Daniel Rueckert74 Martin Rusnák126, Juan Sahuquillo116, Oliver Sakowitz102, 127, Renan Sanchez-Porras127, Janos Sandor128, Nadine Schäfer93, Silke Schmidt129, Herbert Schoechl130, Guus Schoonman131, Rico Frederik Schou132, Elisabeth Schwendenwein22, Charlie Sewalt77, Ranjit D. Singh113, Toril Skandsen133, 134, Peter Smielewski41, Abayomi Sorinola135, Emmanuel Stamatakis60, Simon Stanworth53, Robert Stevens136, William Stewart137, Ewout W. Steyerberg77, 138, Nino Stocchetti139, Nina Sundström140, Riikka Takala141, Viktória Tamás135, Tomas Tamosuitis142, Mark Steven Taylor35, Braden Te Ao65, Olli Tenovuo12,13, Alice Theadom65, Matt Thomas99, Dick Tibboel143, Marjolein Timmers86, Christos Tolias144, Tony Trapani43, Cristina Maria Tudora105, Andreas Unterberg102, Peter Vajkoczy 145, Shirley Vallance43, Egils Valeinis73, Zoltán Vámos63, Mathieu van der Jagt146, Gregory Van der Steen56, Joukje van der Naalt83, Jeroen T.J.M. van Dijck 113, Inge A. M. van Erp113, Thomas A. van Essen113, Wim Van Hecke147, Caroline van Heugten148, Dominique Van Praag149, Ernest van Veen77, Thijs Vande Vyvere147, Roel P. J. van Wijk113, Alessia Vargiolu47, Emmanuel Vega95, Kimberley Velt77, Jan Verheyden147, Paul M. Vespa150, Anne Vik133, 151, Rimantas Vilcinis142, Victor Volovici80, Nicole von Steinbüchel2, Daphne Voormolen77, Petar Vulekovic59, Kevin K.W. Wang152, Daniel Whitehouse60, Eveline Wiegers77, Guy Williams60, Lindsay Wilson81, Stefan Winzeck60, Stefan Wolf153, Zhihui Yang123, Peter Ylén154, Alexander Younsi102, Frederick A. Zeiler60,155, Veronika Zelinkova35, Agate Ziverte73, Tommaso Zoerle42
18 Department of Physiology and Pharmacology, Section of Perioperative Medicine and Intensive Care, Karolinska Institutet, Stockholm, Sweden
19 János Szentágothai Research Centre, University of Pécs, Pécs, Hungary
20 Department of Neurosurgery, University Hospital Northern Norway, Tromso, Norway
21 Department of Physical Medicine and Rehabilitation, University Hospital Northern Norway, Tromso, Norway
22 Trauma Surgery, Medical University Vienna, Vienna, Austria
23 Department of Anesthesiology & Intensive Care, University Hospital Nancy, Nancy, France
24 Department of Anesthesiology & Intensive Care, S Raffaele University Hospital, Milan, Italy
25 Department of Neurosurgery, Radboud University Medical Center, Nijmegen, The Netherlands
26 Department of Neurosurgery, University of Szeged, Szeged, Hungary
27 International Projects Management, ARTTIC, Munchen, Germany
28 Department of Neurology, Neurological Intensive Care Unit, Medical University of Innsbruck, Innsbruck, Austria
29 Department of Neurosurgery & Anesthesia & intensive care medicine, Karolinska University Hospital, Stockholm, Sweden
30 NIHR Surgical Reconstruction and Microbiology Research Centre, Birmingham, UK
31 Anesthesie-Réanimation, Assistance Publique – Hopitaux de Paris, Paris, France
32 Department of Anesthesia & ICU, AOU Città della Salute e della Scienza di Torino - Orthopedic and Trauma Center, Torino, Italy
33 Department of Neurology, Odense University Hospital, Odense, Denmark
34 BehaviourWorks Australia, Monash Sustainability Institute, Monash University, Victoria, Australia
35 Department of Public Health, Faculty of Health Sciences and Social Work, Trnava University, Trnava, Slovakia
36 Quesgen Systems Inc., Burlingame, California, USA
37 Australian & New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia
38 Department of Surgery and Perioperative Science, Umeå University, Umeå, Sweden.
39 Department of Neurosurgery, Medical School, University of Pécs, Hungary and Neurotrauma Research Group, János Szentágothai Research Centre, University of Pécs, Hungary
40 Department of Medical Psychology, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany
41 Brain Physics Lab, Division of Neurosurgery, Dept of Clinical Neurosciences, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK
42 Neuro ICU, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy
43 ANZIC Research Centre, Monash University, Department of Epidemiology and Preventive Medicine, Melbourne, Victoria, Australia
44 Department of Neurosurgery, Hospital of Cruces, Bilbao, Spain
45 NeuroIntensive Care, Niguarda Hospital, Milan, Italy
46 School of Medicine and Surgery, Università Milano Bicocca, Milano, Italy
47 NeuroIntensive Care, ASST di Monza, Monza, Italy
48 Department of Neurosurgery, Medical Faculty RWTH Aachen University, Aachen, Germany.
49 Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany
50 Department of Anesthesia & Neurointensive Care, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK.
52 School of Public Health & PM, Monash University and The Alfred Hospital, Melbourne, Victoria, Australia
52 Radiology/MRI department, MRC Cognition and Brain Sciences Unit, Cambridge, UK
53 Oxford University Hospitals NHS Trust, Oxford, UK
54 Intensive Care Unit, CHU Poitiers, Potiers, France
55 University of Manchester NIHR Biomedical Research Centre, Critical Care Directorate, Salford Royal Hospital NHS Foundation Trust, Salford, UK
56 Department of Neurosurgery, Antwerp University Hospital and University of Antwerp, Edegem, Belgium
57 Department of Anesthesia & Intensive Care, Maggiore Della Carità Hospital, Novara, Italy
58 Department of Neurosurgery, University Hospitals Leuven, Leuven, Belgium
59 Department of Neurosurgery, Clinical centre of Vojvodina, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia
60 Division of Anaesthesia, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK
61 Center for Stroke Research Berlin, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
62 Intensive Care Unit, CHR Citadelle, Liège, Belgium
63 Department of Anaesthesiology and Intensive Therapy, University of Pécs, Pécs, Hungary
64 Departments of Neurology, Clinical Neurophysiology and Neuroanesthesiology, Region Hovedstaden Rigshospitalet, Copenhagen, Denmark
65 National Institute for Stroke and Applied Neurosciences, Faculty of Health and Environmental Studies, Auckland University of Technology, Auckland, New Zealand
66 Department of Neurology, Erasmus MC, Rotterdam, the Netherlands
67 Department of Anesthesiology and Intensive care, University Hospital Northern Norway, Tromso, Norway
68 Department of Neurosurgery, Hadassah-hebrew University Medical center, Jerusalem, Israel
69 Fundación Instituto Valenciano de Neurorrehabilitación (FIVAN), Valencia, Spain
70 Department of Neurosurgery, Shanghai Renji hospital, Shanghai Jiaotong University/school of medicine, Shanghai, China
71 Karolinska Institutet, INCF International Neuroinformatics Coordinating Facility, Stockholm, Sweden
72 Emergency Department, CHU, Liège, Belgium
73 Neurosurgery clinic, Pauls Stradins Clinical University Hospital, Riga, Latvia
74 Department of Computing, Imperial College London, London, UK
75 Department of Neurosurgery, Hospital Universitario 12 de Octubre, Madrid, Spain
76 Department of Anesthesia, Critical Care and Pain Medicine, Medical University of Vienna, Austria
77 Department of Public Health, Erasmus Medical Center-University Medical Center, Rotterdam, The Netherlands
78 College of Health and Medicine, Australian National University, Canberra, Australia
79 Department of Neurosurgery, Neurosciences Centre & JPN Apex trauma centre, All India Institute of Medical Sciences, New Delhi-110029, India
80 Department of Neurosurgery, Erasmus MC, Rotterdam, the Netherlands
81 Division of Psychology, University of Stirling, Stirling, UK
82 Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke’s Hospital & University of Cambridge, Cambridge, UK.
83 Department of Neurology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands
84 Neurointensive Care , Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
85 Salford Royal Hospital NHS Foundation Trust Acute Research Delivery Team, Salford, UK
86 Department of Intensive Care and Department of Ethics and Philosophy of Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
87 Department of Clinical Neuroscience, Neurosurgery, Umeå University, Umeå, Sweden.
88 Hungarian Brain Research Program - Grant No. KTIA_13_NAP-A-II/8, University of Pécs, Pécs, Hungary
89 Department of Anaesthesiology, University Hospital of Aachen, Aachen, Germany
90 Cyclotron Research Center , University of Liège, Liège, Belgium
91 Centre for Urgent and Emergency Care Research (CURE), Health Services Research Section, School of Health and Related Research (ScHARR), University of Sheffield, Sheffield, UK
92 Emergency Department, Salford Royal Hospital, Salford UK
93 Institute of Research in Operative Medicine (IFOM), Witten/Herdecke University, Cologne, Germany
94 VP Global Project Management CNS, ICON, Paris, France
95 Department of Anesthesiology-Intensive Care, Lille University Hospital, Lille, France
96 Department of Neurosurgery, Rambam Medical Center, Haifa, Israel
97 Department of Anesthesiology & Intensive Care, University Hospitals Southhampton NHS Trust, Southhampton, UK
98 Cologne-Merheim Medical Center (CMMC), Department of Traumatology, Orthopedic Surgery and Sportmedicine, Witten/Herdecke University, Cologne, Germany
99 Intensive Care Unit, Southmead Hospital, Bristol, Bristol, UK
100 Department of Neurological Surgery, University of California, San Francisco, California, USA
101 Department of Anesthesia & Intensive Care,M. Bufalini Hospital, Cesena, Italy
102 Department of Neurosurgery, University Hospital Heidelberg, Heidelberg, Germany
103 Department of Neurosurgery, The Walton centre NHS Foundation Trust, Liverpool, UK
104 Department of Medical Genetics, University of Pécs, Pécs, Hungary
105 Department of Neurosurgery, Emergency County Hospital Timisoara , Timisoara, Romania
106 School of Medical Sciences, Örebro University, Örebro, Sweden.
107 Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland
108 Analytic and Translational Genetics Unit, Department of Medicine; Psychiatric & Neurodevelopmental Genetics Unit, Department of Psychiatry; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA
109 Program in Medical and Population Genetics; The Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA
110 Department of Radiology, University of Antwerp, Edegem, Belgium
111 Department of Anesthesiology & Intensive Care, University Hospital of Grenoble, Grenoble, France
112 Department of Anesthesia & Intensive Care, Azienda Ospedaliera Università di Padova, Padova, Italy
113 Dept. of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands and Dept. of Neurosurgery, Medical Center Haaglanden, The Hague, The Netherlands
114 Department of Neurosurgery, Helsinki University Central Hospital
115 Department of Anesthesiology and Critical Care, Pitié -Salpêtrière Teaching Hospital, Assistance Publique, Hôpitaux de Paris and University Pierre et Marie Curie, Paris, France
116 Neurotraumatology and Neurosurgery Research Unit (UNINN), Vall d'Hebron Research Institute, Barcelona, Spain
117 Department of Neurosurgery, Kaunas University of technology and Vilnius University, Vilnius, Lithuania
118 Department of Neurosurgery, Rezekne Hospital, Latvia
119 Department of Anaesthesia, Critical Care & Pain Medicine NHS Lothian & University of Edinburg, Edinburgh, UK
120 Director, MRC Biostatistics Unit, Cambridge Institute of Public Health, Cambridge, UK
121 Division of Orthopedics, Oslo University Hospital, Oslo, Norway
122 Institue of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway
123 Broad Institute, Cambridge MA Harvard Medical School, Boston MA, Massachusetts General Hospital, Boston MA, USA
124 National Trauma Research Institute, The Alfred Hospital, Monash University, Melbourne, Victoria, Australia
125 Department of Neurosurgery, Odense University Hospital, Odense, Denmark
126 International Neurotrauma Research Organisation, Vienna, Austria
127 Klinik für Neurochirurgie, Klinikum Ludwigsburg, Ludwigsburg, Germany
128 Division of Biostatistics and Epidemiology, Department of Preventive Medicine, University of Debrecen, Debrecen, Hungary
129 Department Health and Prevention, University Greifswald, Greifswald, Germany
130 Department of Anaesthesiology and Intensive Care, AUVA Trauma Hospital, Salzburg, Austria
131 Department of Neurology, Elisabeth-TweeSteden Ziekenhuis, Tilburg, the Netherlands
132 Department of Neuroanesthesia and Neurointensive Care, Odense University Hospital, Odense, Denmark
133 Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, NTNU, Trondheim, Norway
134 Department of Physical Medicine and Rehabilitation, St.Olavs Hospital, Trondheim University Hospital, Trondheim, Norway
135 Department of Neurosurgery, University of Pécs, Pécs, Hungary
136 Division of Neuroscience Critical Care, John Hopkins University School of Medicine, Baltimore, USA
137 Department of Neuropathology, Queen Elizabeth University Hospital and University of Glasgow, Glasgow, UK
138 Dept. of Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands
139 Department of Pathophysiology and Transplantation, Milan University, and Neuroscience ICU, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milano, Italy
140 Department of Radiation Sciences, Biomedical Engineering, Umeå University, Umeå, Sweden.
141 Perioperative Services, Intensive Care Medicine and Pain Management, Turku University Hospital and University of Turku, Turku, Finland
142 Department of Neurosurgery, Kaunas University of Health Sciences, Kaunas, Lithuania
143 Intensive Care and Department of Pediatric Surgery, Erasmus Medical Center, Sophia Children’s Hospital, Rotterdam, The Netherlands
144 Department of Neurosurgery, Kings college London, London, UK
145 Neurologie, Neurochirurgie und Psychiatrie, Charité – Universitätsmedizin Berlin, Berlin, Germany
146 Department of Intensive Care Adults, Erasmus MC– University Medical Center Rotterdam, Rotterdam, the Netherlands.
147 icoMetrix NV, Leuven, Belgium
148 Movement Science Group, Faculty of Health and Life Sciences, Oxford Brookes University, Oxford, UK
149 Psychology Department, Antwerp University Hospital, Edegem, Belgium
150 Director of Neurocritical Care, University of California, Los Angeles, USA
151 Department of Neurosurgery, St.Olavs Hospital, Trondheim University Hospital, Trondheim, Norway
152 Department of Emergency Medicine, University of Florida, Gainesville, Florida, USA
153 Department of Neurosurgery, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
154 VTT Technical Research Centre, Tampere, Finland.
155 Section of Neurosurgery, Department of Surgery, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada