Background
Methods
Study population
Data collection
Statistical analysis
Results
Subject characteristics
Variable | Cases (N = 73) | Controls (N = 157) | P value |
---|---|---|---|
Age, years, mean ± SD | 63.4 ± 10.3 | 62.7 ± 11.4 | 0.656 |
Education less than middle school, n (%) * | 19 (26.0) | 23 (14.6) | 0.038 |
Never employed, n (%) * | 15 (20.5) | 17 (10.8) | 0.047 |
Smoking, n (%) | 6 (8.2) | 8 (5.1) | 0.356 |
High alcohol intake, n (%) | 5 (6.8) | 9 (5.7) | 0.742 |
Reflux, n (%) * | 29 (39.7) | 16 (10.2) | <0.001 |
Overweight or obesity, n (%) | 28 (38.4) | 63 (40.1) | 0.798 |
Low consumption of fresh vegetables, n (%) | 6 (8.2) | 10 (6.4) | 0.891 |
Low consumption of fresh fruits, n (%) | 10 (13.7) | 17 (10.8) | 0.529 |
Reproductive factors and risk of oesophageal cancer
Variable | Controls n (%) | All types of oesophageal cancer | Squamous cell oesophageal cancer | ||||
---|---|---|---|---|---|---|---|
Cases n (%) | Crude OR (95% CI) | Adjusted OR* (95% CI) | Cases n (%) | Crude OR (95% CI) | Adjusted OR* (95% CI) | ||
Children | |||||||
No | 23 | 9 | 1 | 1 | 8 | 1 | 1 |
Yes | 134 | 64 | 1.22 (0.53, 2.78) | 1.17 (0.48, 2.85) | 60 | 1.29 (0.54, 3.04) | 1.20 (0.47, 3.36) |
Number of children born | |||||||
0 | 23 | 9 | 1 | 1 | 8 | 1 | 1 |
1 or 2 | 88 | 45 | 1.26 (0.71, 2.22) | 1.31 (0.72, 2.35) | 43 | 1.40 (0.58, 3.39) | 1.34 (0.67, 2.68) |
3 or more | 46 | 19 | 1.02 (0.51, 2.03) | 1.03 (0.49, 2.14) | 17 | 1.06 (0.40, 2.82) | 1.02 (0.38, 2.74) |
Age at first birth | |||||||
<22 years | 51 | 17 | 1 | 1 | 15 | 1 | 1 |
22-24 years | 46 | 20 | 1.30 (0.61, 2.78) | 1.27 (0.54, 2.98) | 19 | 1.40 (0.64, 3.08) | 1.31 (0.50, 3.43) |
>24 years | 37 | 27 | 2.19 (1.05, 4.58) | 2.02 (1.01, 4.04) | 26 | 2.39 (1.11, 5.12) | 2.12 (1.02, 4.41) |
Spontaneous abortion | |||||||
No | 129 | 55 | 1 | 1 | 51 | 1 | 1 |
Yes | 28 | 18 | 1.51 (0.77, 2.94) | 1.37 (0.49, 3.83) | 17 | 1.54 (0.77, 3.04) | 1.39 (0.50, 3.86) |
Age at menarche | |||||||
<12 years | 19 | 11 | 1 | 1 | 10 | 1 | 1 |
12-16 years | 128 | 47 | 0.63 (0.28, 1.43) | 0.81 (0.38, 1.86) | 44 | 0.65 (0.28, 1.51) | 0.80 (0.37, 1.72) |
>16 years | 10 | 15 | 2.59 (0.87, 7.71) | 2.15 (0.77, 6.00) | 14 | 2.66 (0.87, 8.11) | 2.19 (0.79, 6.07) |
Age at menopause | |||||||
<46 years | 44 | 19 | 1 | 1 | 18 | 1 | 1 |
46-48 years | 55 | 31 | 1.31 (0.65, 2.61) | 1.12 (0.40, 3.14) | 29 | 1.29 (0.63, 2.61) | 1.10 (0.35, 2.86) |
>48 years | 58 | 23 | 0.92 (0.45, 1.89) | 0.96 (0.33, 2.79) | 21 | 0.89 (0.42, 1.85) | 0.94 (0.31, 2.85) |
Years of menstruation | |||||||
<32 years | 41 | 20 | 1 | 1 | 19 | 1 | 1 |
33-36 years | 60 | 28 | 0.96 (0.48, 1.92) | 0.94 (0.41, 2.15) | 25 | 0.90 (0.44, 1.84) | 0.91 (0.39, 2.12) |
>36 years | 56 | 25 | 0.92 (0.45, 1.86) | 0.93 (0.38, 2.27) | 24 | 0.92 (0.45, 1.90) | 0.92 (0.35, 2.42) |