Erschienen in:
13.11.2023 | Response to Letter To The Editor
Response to “Letter to the Editor for ‘Hypertonic Saline Versus Other Intracranial-Pressure-Lowering Agents for Patients with Acute Traumatic Brain Injury: A Systematic Review and Meta-analysis’”
verfasst von:
Keeley Bernhardt, William McClune, Matthew J. Rowland, Akshay Shah
Erschienen in:
Neurocritical Care
|
Ausgabe 1/2024
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Excerpt
We thank Dr. Shamin for their interest in our systematic review and meta-analysis [
1]. We disagree with their statement that 3% hypertonic saline (HTS) in patients with acute traumatic brain injury (TBI) is the most effective modality in reducing elevated intracranial pressure (ICP). We wish to clarify that we do not state that HTS is more effective that its comparators in our review. The central conclusion was that there is currently no evidence of an effect of HTS compared with other ICP-lowering agents for our primary outcome (Glasgow Outcome Scale score at 6 months) and other outcomes of interest, including ICP reduction and uncontrolled ICP. …