Erschienen in:
01.12.2015 | Anxiety, Obsessive Compulsive and Related Disorders (B Brennan and D Dougherty, Section Editors)
Review of Psychopharmacological Approaches for Trichotillomania and Other Body-Focused Behaviors
verfasst von:
Jon E. Grant, J.D., M.D., M.P.H.
Erschienen in:
Current Treatment Options in Psychiatry
|
Ausgabe 4/2015
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Opinion statement
N-acetyl cysteine (NAC) is a safe, generally well-tolerated option for these disorders, and so I usually suggest a trial of NAC. If after 3 months and no response, I consider other options. If the person has urges to pull or pick and they have first-degree relatives with addictions, then I suggest a trial of naltrexone. If they have significant anxiety or depression co-occurring with the pulling, I often suggest clomipramine as a possible treatment for both conditions. In the case of skin picking with co-occurring depression or anxiety, I recommend a selective serotonin reuptake inhibitor (SSRI). Although we only have open-label data to support its use, I often use dronabinol in individuals who pick or pull most of the time unconsciously. Finally, I might suggest an antipsychotic for some people who have failed all else. Due to the side effects of antipsychotic medications, I use these only as a last resort.