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Erschienen in: International Journal of Hematology 5/2015

01.11.2015 | Case Report

Romiplostim for secondary thrombocytopenia following allogeneic stem cell transplantation in children

verfasst von: Natalia Maximova, D. Zanon, F. Rovere, A. Maestro, G. Schillani, R. Paparazzo

Erschienen in: International Journal of Hematology | Ausgabe 5/2015

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Abstract

The outcome of romiplostim for secondary failure of platelet recovery (SFPR) was investigated in children who had undergone hematopoietic stem cell transplantation (HSCT). Seven transfusion-dependent pediatric patients (median age 11 years), with platelet counts below 10 × 109/L, received four weekly doses of subcutaneous romiplostim to treat SFPR developed after HSCT. All patients, except one (patient 4), became platelet transfusion-independent in the second week from the beginning of treatment and no patient needed to discontinue drug treatment because of adverse events. Romiplostim could represent a beneficial first-line treatment, but further studies are required.
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Metadaten
Titel
Romiplostim for secondary thrombocytopenia following allogeneic stem cell transplantation in children
verfasst von
Natalia Maximova
D. Zanon
F. Rovere
A. Maestro
G. Schillani
R. Paparazzo
Publikationsdatum
01.11.2015
Verlag
Springer Japan
Erschienen in
International Journal of Hematology / Ausgabe 5/2015
Print ISSN: 0925-5710
Elektronische ISSN: 1865-3774
DOI
https://doi.org/10.1007/s12185-015-1821-1

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