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20.07.2018 | Original Article

Salivary adiponectin, but not adenosine deaminase, correlates with clinical signs in women with Sjögren’s syndrome: a pilot study

verfasst von: Asta Tvarijonaviciute, Carmen Zamora, Silvia Martinez-Subiela, Fernando Tecles, Francisca Pina, Pia Lopez-Jornet

Erschienen in: Clinical Oral Investigations | Ausgabe 3/2019

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Abstract

Objectives

To evaluate salivary adiponectin and adenosine deaminase (ADA) in women suffering from Sjögren’s syndrome (SS).

Methods

Salivary adiponectin and ADA were measured in patients with SS (n = 17) and compared to their values in healthy controls (n = 13) and patients suffering from drug-induced xerostomia (non-SS sicca group; n = 19). A clinical history was made for each patient, patients were examined clinically, and xerostomia inventory (XI) was performed.

Results

Salivary adiponectin corrected by total protein was higher in patients with SS than in healthy individuals (P < 0.05) or patients with non-SS sicca (P < 0.01) and correlated with XI (r = 0.555; P < 0.05). Salivary ADA was higher in patients with SS and non-SS sicca compared to controls (P < 0.05 in both cases).

Conclusion

The results of the present study indicate that adiponectin and ADA are increased in the saliva of patients with SS.

Clinical relevance

Salivary adiponectin corrected by total protein can be a potential biomarker of SS.

Trial registration

NCT03156569

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Titel: Salivary adiponectin, but not adenosine deaminase, correlates with clinical signs in women with Sjögren’s syndrome: a pilot study
verfasst von: Asta Tvarijonaviciute
Carmen Zamora
Silvia Martinez-Subiela
Fernando Tecles
Francisca Pina
Pia Lopez-Jornet
Publikationsdatum: 20.07.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: Clinical Oral Investigations / Ausgabe 3/2019
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-018-2570-3

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Salivary adiponectin, but not adenosine deaminase, correlates with clinical signs in women with Sjögren’s syndrome: a pilot study

Abstract

Objectives

Methods

Results

Conclusion

Clinical relevance

Trial registration

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Abstract

Objectives

Methods

Results

Conclusion

Clinical relevance

Trial registration

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