Erschienen in:
01.03.2016 | Original Article
Serostatus of Epstein–Barr virus in Iranian MS patients
verfasst von:
Sajad Karampoor, Hamid Zahednasab, Angila Ataei Pirkouh, Seyed Hamid Reza Monavari, Sreeram Ramagopalan, Hossein Keyvani
Erschienen in:
Acta Neurologica Belgica
|
Ausgabe 1/2016
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Abstract
Multiple sclerosis (MS) is a common, complex disorder. Associations of MS with Epstein–Barr virus (EBV) infection in Caucasian populations are well documented. However, in the Iranian population, previous studies have been conflicting. Sixty patients with MS and 50 healthy controls were tested for anti-EBV antibodies using chemiluminescent assays. All MS patients to be seropositive for EBV as compared to 82 % of controls (p = 0.0006). A strong, significant association of MS with EBV infection was documented, similar to studies in first world populations. Future studies should investigate the temporal sequence of infection to try to understand the cause of the recent increase in MS risk in Iran.