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Rheumatology International

Erschienen in:

04.05.2022 | Imaging

Shear wave elastography as a potential additional diagnostic tool in primary Sjögren’s syndrome: an observational study

verfasst von: Marta Świecka, Łukasz Paluch, Piotr Pietruski, Maria Maślińska, Jakub Zakrzewski, Brygida Kwiatkowska

Erschienen in: Rheumatology International | Ausgabe 9/2022

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Abstract

The primary aim of this study was to verify if shear wave elastography can be used to evaluate salivary gland involvement in primary Sjögren's syndrome (pSS). The secondary objective was to establish an accurate cut-off value for parotid and submandibular salivary gland stiffness and to verify whether there are any distinctions among pSS patients with or without subjective mouth dryness. This prospective study included 45 patients with pSS (2016 ACR/EULAR classification criteria) and 108 healthy controls. All subjects underwent bilateral shear wave elastography of the parotid and submandibular salivary glands. Clinical data of pSS patients were collected and compared to elastography results. Patients with pSS had significantly higher shear wave elastography values for the parotid and submandibular salivary glands than the controls. There were no statistical differences in SWE values between patients with or without mouth dryness. The optimal cut-off value (mean value of 4 salivary glands shear wave elastography results) to distinguish patients with or without pSS was 13.19 kPa with sensitivity = 97.8% and specificity = 100.0%. It was, therefore, confirmed that shear wave elastography measurement of salivary glands has strong predictive ability in pSS detection (AUC 97.8%, 95% CI 93.4–100.0%). Shear wave elastography seems to be a promising, non-invasive and simple quantitative adjunct test to support the diagnosis of pSS with good sensitivity and specificity. More extensive prospective studies are needed to standardize a study protocol.

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Titel: Shear wave elastography as a potential additional diagnostic tool in primary Sjögren’s syndrome: an observational study
verfasst von: Marta Świecka
Łukasz Paluch
Piotr Pietruski
Maria Maślińska
Jakub Zakrzewski
Brygida Kwiatkowska
Publikationsdatum: 04.05.2022
Verlag: Springer Berlin Heidelberg
Erschienen in: Rheumatology International / Ausgabe 9/2022
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI: https://doi.org/10.1007/s00296-022-05120-5

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