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Endocrine
Erschienen in: Endocrine 2/2016

01.02.2016 | Original Article

Smell–taste dysfunctions in extreme weight/eating conditions: analysis of hormonal and psychological interactions

verfasst von: Fernando Fernández-Aranda, Zaida Agüera, Jose C. Fernández-García, Lourdes Garrido-Sanchez, Juan Alcaide-Torres, Francisco J. Tinahones, Cristina Giner-Bartolomé, Rosa M. Baños, Cristina Botella, Ausias Cebolla, Rafael de la Torre, Jose M. Fernández-Real, Francisco J. Ortega, Gema Frühbeck, Javier Gómez-Ambrosi, Roser Granero, Mohamed A. Islam, Susana Jiménez-Murcia, Salomé Tárrega, José M. Menchón, Ana B. Fagundo, Carolina Sancho, Xavier Estivill, Janet Treasure, Felipe F. Casanueva

Erschienen in: Endocrine | Ausgabe 2/2016

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Abstract

(1) The objective of this study is to analyze differences in smell–taste capacity between females in extreme weight/eating conditions (EWC) and (2) to explore the interaction between smell/taste capacity, gastric hormones, eating behavior and body mass index (BMI). The sample comprised 239 females in EWC [64 Anorexia nervosa (AN) and 80 age-matched healthy-weight controls, and 59 obese and 36 age-matched healthy-weight controls]. Smell and taste assessments were performed through “Sniffin’ Sticks” and “Taste Strips,” respectively. The assessment measures included the eating disorders inventory-2, the symptom check list 90-revised, and The Dutch Eating Behavior Questionnaire, as well as peptides from the gastrointestinal tract [Ghrelin, peptide YY, cholecystokinin]. Smell capacity was differentially associated across EWC groups. Smell was clearly impaired in obese participants and increased in AN (hyposmia in Obesity was 54.3 and 6.4 % in AN), but taste capacity did not vary across EWC. Ghrelin levels were significantly decreased in obese subjects and were related to smell impairment. EWC individuals showed a distinct smell profile and circulating ghrelin levels compared to controls. Smell capacity and ghrelin may act as moderators of emotional eating and BMI.
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Metadaten
Titel
Smell–taste dysfunctions in extreme weight/eating conditions: analysis of hormonal and psychological interactions
verfasst von
Fernando Fernández-Aranda
Zaida Agüera
Jose C. Fernández-García
Lourdes Garrido-Sanchez
Juan Alcaide-Torres
Francisco J. Tinahones
Cristina Giner-Bartolomé
Rosa M. Baños
Cristina Botella
Ausias Cebolla
Rafael de la Torre
Jose M. Fernández-Real
Francisco J. Ortega
Gema Frühbeck
Javier Gómez-Ambrosi
Roser Granero
Mohamed A. Islam
Susana Jiménez-Murcia
Salomé Tárrega
José M. Menchón
Ana B. Fagundo
Carolina Sancho
Xavier Estivill
Janet Treasure
Felipe F. Casanueva
Publikationsdatum
01.02.2016
Verlag
Springer US
Erschienen in
Endocrine / Ausgabe 2/2016
Print ISSN: 1355-008X
Elektronische ISSN: 1559-0100
DOI
https://doi.org/10.1007/s12020-015-0684-9

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