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Erschienen in: Journal of Gastrointestinal Cancer 2/2010

01.06.2010 | Review Article

Solitary True Cyst of Pancreas: Report of a Case and Review of Literature

verfasst von: Mohammad Atif Khan, G. R. Verma

Erschienen in: Journal of Gastrointestinal Cancer | Ausgabe 2/2010

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Abstract

Context

Solitary true cysts of the pancreas in adults are extremely rare, and only few cases have been reported in the literature. The etiology and natural history of these lesions remain unknown, and treatment is not standardized. We describe an additional resected case.

Case reports

A 55-year-old female who presented to us with a history of heaviness and pain in right upper abdomen for 1 year. CT scan of abdomen showed a large unilocular cyst in the region of the head of the pancreas. The patient underwent pancreatico-duodenectomy with binding pancreaticojejunostomy. The histology of cyst revealed true unilocular pancreatic cyst lined by cuboidal epithelium. She is well after 3 years of follow-up.

Conclusions

A preoperative work-up alone does not always allow an accurate diagnosis, but it is useful in determining lesion characteristics and guiding therapeutic decision-making. When surgery is indicated, a limited resection is warranted in most cases.
Literatur
1.
Zurück zum Zitat Bradley EL, Clements JL, Gonzalez AC. The natural history of pancreatic pseudocyst: a unified concept of management. Am J Surg. 1979;137:135–41.CrossRefPubMed Bradley EL, Clements JL, Gonzalez AC. The natural history of pancreatic pseudocyst: a unified concept of management. Am J Surg. 1979;137:135–41.CrossRefPubMed
2.
Zurück zum Zitat Hulke J. Pancreatic cyst. Lancet. 1892;23:1309–12. Hulke J. Pancreatic cyst. Lancet. 1892;23:1309–12.
3.
Zurück zum Zitat Niggard KK, Stacy LJ. Solitary congenital (dysontogenetic) cyst of the pancreas. Report of a case. Arch Surg. 1942;45:206–12. Niggard KK, Stacy LJ. Solitary congenital (dysontogenetic) cyst of the pancreas. Report of a case. Arch Surg. 1942;45:206–12.
4.
Zurück zum Zitat Jordan Jr GL. Pancreatic cyst. In: Howard JM, Jordan Jr GL, editors. Surgical diseases of pancreas. Philadelphia: JB Lippincott; 1960. p. 283–320. Jordan Jr GL. Pancreatic cyst. In: Howard JM, Jordan Jr GL, editors. Surgical diseases of pancreas. Philadelphia: JB Lippincott; 1960. p. 283–320.
5.
Zurück zum Zitat Wolloch Y, Chaimoff C, Lubin E, et al. Splenic vein thrombosis, segmental portal hypertension, and bleeding esophageal varices produced by congenital pancreatic cyst. Israel J Med Sci. 1974;10:670–3.PubMed Wolloch Y, Chaimoff C, Lubin E, et al. Splenic vein thrombosis, segmental portal hypertension, and bleeding esophageal varices produced by congenital pancreatic cyst. Israel J Med Sci. 1974;10:670–3.PubMed
6.
Zurück zum Zitat Mao C, Greenwood S, Wagner S, et al. Solitary true cyst of pancreas in an adult. Int J Pancreatol. 1992;12:181–6.PubMed Mao C, Greenwood S, Wagner S, et al. Solitary true cyst of pancreas in an adult. Int J Pancreatol. 1992;12:181–6.PubMed
7.
Zurück zum Zitat Sperti C, Pasquali C, Constantino V, et al. Solitary true cyst of pancreas in adults. Int J Pancreatol. 1995;18:161–7.PubMed Sperti C, Pasquali C, Constantino V, et al. Solitary true cyst of pancreas in adults. Int J Pancreatol. 1995;18:161–7.PubMed
8.
Zurück zum Zitat Spinelli KS, Fromwiller TE, Daniel RA, et al. Cystic pancreatic neoplasm. Observe or operate. Ann Surg. 2004;239:651–9.CrossRefPubMed Spinelli KS, Fromwiller TE, Daniel RA, et al. Cystic pancreatic neoplasm. Observe or operate. Ann Surg. 2004;239:651–9.CrossRefPubMed
9.
10.
Zurück zum Zitat Goh BK, Tan YM, Cheow PC, et al. Cystic neoplasms of the pancreas with mucin-production. Eur J Surg Oncol. 2005;31:282–7.CrossRefPubMed Goh BK, Tan YM, Cheow PC, et al. Cystic neoplasms of the pancreas with mucin-production. Eur J Surg Oncol. 2005;31:282–7.CrossRefPubMed
11.
Zurück zum Zitat Ooi LL, Ho GH, Chew SP, et al. Cystic tumours of the pancreas: a diagnostic dilemma. Aust NZ J Surg. 1998;68:844–6. Ooi LL, Ho GH, Chew SP, et al. Cystic tumours of the pancreas: a diagnostic dilemma. Aust NZ J Surg. 1998;68:844–6.
12.
Zurück zum Zitat Horvath K, Chabot JA. An aggressive resectional approach to cystic neoplasms of the pancreas. Am J Surg. 1999;178:269–74.CrossRefPubMed Horvath K, Chabot JA. An aggressive resectional approach to cystic neoplasms of the pancreas. Am J Surg. 1999;178:269–74.CrossRefPubMed
13.
Zurück zum Zitat Fernandez-del Castillo C, Warshaw AL. Cystic tumors of the pancreas. Surg Clin North Am. 1995;75:1001–16.PubMed Fernandez-del Castillo C, Warshaw AL. Cystic tumors of the pancreas. Surg Clin North Am. 1995;75:1001–16.PubMed
14.
Zurück zum Zitat Fernandez-del Castillo C, Warshaw AL. Current management of cystic neoplasms of the pancreas. Adv Surg. 2000;34:237–48.PubMed Fernandez-del Castillo C, Warshaw AL. Current management of cystic neoplasms of the pancreas. Adv Surg. 2000;34:237–48.PubMed
15.
Zurück zum Zitat Allen PJ, Jaques DP, D’Angelica M, et al. Cystic lesions of the pancreas: selection criteria for operative and nonoperative management in 209 patients. J Gastrointest Surg. 2003;7:970.CrossRefPubMed Allen PJ, Jaques DP, D’Angelica M, et al. Cystic lesions of the pancreas: selection criteria for operative and nonoperative management in 209 patients. J Gastrointest Surg. 2003;7:970.CrossRefPubMed
16.
Zurück zum Zitat Goh BK, Tan YM, Chung YF, et al. (2010) Non-neoplastic pancreatic cystic and cystic-like lesions of the pancreas: unusual mimickers of pancreatic cystic neoplasms. ANZ J Surg (in press). Goh BK, Tan YM, Chung YF, et al. (2010) Non-neoplastic pancreatic cystic and cystic-like lesions of the pancreas: unusual mimickers of pancreatic cystic neoplasms. ANZ J Surg (in press).
17.
Zurück zum Zitat Goh BK, Tan YM, Tan PH, et al. Mucinous nonneoplastic cyst: a truly novel pathological entity? World J Gastroenterol. 2005;11:2045–7.PubMed Goh BK, Tan YM, Tan PH, et al. Mucinous nonneoplastic cyst: a truly novel pathological entity? World J Gastroenterol. 2005;11:2045–7.PubMed
18.
Zurück zum Zitat Fernandez-del Castillo C, Targarona J, Thayer SP, et al. Incidental pancreatic cysts. Clinicopathologic characteristics and comparison with symptomatic patients. Arch Surg. 2003;138:427–34.CrossRefPubMed Fernandez-del Castillo C, Targarona J, Thayer SP, et al. Incidental pancreatic cysts. Clinicopathologic characteristics and comparison with symptomatic patients. Arch Surg. 2003;138:427–34.CrossRefPubMed
19.
Zurück zum Zitat Brugge WR, Lauwers GY, Sahani D, et al. Cystic neoplasms of the pancreas. N Engl J Med. 2004;351:1218–26.CrossRefPubMed Brugge WR, Lauwers GY, Sahani D, et al. Cystic neoplasms of the pancreas. N Engl J Med. 2004;351:1218–26.CrossRefPubMed
20.
Zurück zum Zitat Kiely JM, Nakeeb A, Komorowski RA, et al. Cystic pancreatic neoplasms: enucleate or resect? J Gastrointest Surg. 2003;7:890–7.CrossRefPubMed Kiely JM, Nakeeb A, Komorowski RA, et al. Cystic pancreatic neoplasms: enucleate or resect? J Gastrointest Surg. 2003;7:890–7.CrossRefPubMed
21.
Zurück zum Zitat Curry CA, Eng J, Horton KM, et al. CT of primary cystic pancreatic neoplasms: can CT be used for patient triage and treatment? AJR Am J Roentgenol. 2000;175:99–103.PubMed Curry CA, Eng J, Horton KM, et al. CT of primary cystic pancreatic neoplasms: can CT be used for patient triage and treatment? AJR Am J Roentgenol. 2000;175:99–103.PubMed
22.
Zurück zum Zitat Sarr MG, Carpenter HA, Prabhakar LP, et al. Clinical and pathologic correlation of 84 mucinous cystic neoplasms of the pancreas. Ann Surg. 2000;231:205–12.CrossRefPubMed Sarr MG, Carpenter HA, Prabhakar LP, et al. Clinical and pathologic correlation of 84 mucinous cystic neoplasms of the pancreas. Ann Surg. 2000;231:205–12.CrossRefPubMed
23.
Zurück zum Zitat Brugge WL, Lewandrowski K, Lee-Lewandrowski E, et al. Diagnosis of pancreatic cystic neoplasms: a report of the cooperative pancreatic cyst study. Gastroenterology. 2004;126:1330–6.CrossRefPubMed Brugge WL, Lewandrowski K, Lee-Lewandrowski E, et al. Diagnosis of pancreatic cystic neoplasms: a report of the cooperative pancreatic cyst study. Gastroenterology. 2004;126:1330–6.CrossRefPubMed
24.
Zurück zum Zitat Goh BK. Diagnosis of pancreatic cystic neoplasms: a report of the cooperative pancreatic cyst study. Gastroenterology. 2005;128:1529–36.CrossRefPubMed Goh BK. Diagnosis of pancreatic cystic neoplasms: a report of the cooperative pancreatic cyst study. Gastroenterology. 2005;128:1529–36.CrossRefPubMed
25.
Zurück zum Zitat Tanno S, Obara T, Izawa T, et al. Solitary true cyst of the pancreas in two adults: analysis of cyst fluid and review of the literature. Am J Gastroenterol. 1998;93:1972–5.CrossRefPubMed Tanno S, Obara T, Izawa T, et al. Solitary true cyst of the pancreas in two adults: analysis of cyst fluid and review of the literature. Am J Gastroenterol. 1998;93:1972–5.CrossRefPubMed
26.
Zurück zum Zitat Jacobsen BC, Baron TH, Adler DG, et al. ASGE guideline: the role of endoscopy in the diagnosis and the management of cystic lesions and inflammatory fluid collections of the pancreas. Gastrointest Endosc. 2005;61:363–70.CrossRef Jacobsen BC, Baron TH, Adler DG, et al. ASGE guideline: the role of endoscopy in the diagnosis and the management of cystic lesions and inflammatory fluid collections of the pancreas. Gastrointest Endosc. 2005;61:363–70.CrossRef
27.
Zurück zum Zitat Goh BK, Tan YM, Chung YF. The utility of fusion CT-PET in the diagnosis of small pancreatic carcinoma with indeterminate findings on US, ERCP, MRI and EUS. World J Gastroenterol. 2005;11:3800–2.PubMed Goh BK, Tan YM, Chung YF. The utility of fusion CT-PET in the diagnosis of small pancreatic carcinoma with indeterminate findings on US, ERCP, MRI and EUS. World J Gastroenterol. 2005;11:3800–2.PubMed
28.
Zurück zum Zitat Sperti C, Pasquali C, Chierichetti F, et al. Value of 18-fluorodeoxyglucose positron emission tomography in the management of patients with cystic tumors of the pancreas. Ann Surg. 2001;234:675–80.CrossRefPubMed Sperti C, Pasquali C, Chierichetti F, et al. Value of 18-fluorodeoxyglucose positron emission tomography in the management of patients with cystic tumors of the pancreas. Ann Surg. 2001;234:675–80.CrossRefPubMed
29.
Zurück zum Zitat Moesinger RC, Talamini MA, Hruban RH, et al. Large cystic pancreatic neoplasms: pathology, respectability, and outcome. Ann Surg Oncol. 1999;6:682–91.CrossRefPubMed Moesinger RC, Talamini MA, Hruban RH, et al. Large cystic pancreatic neoplasms: pathology, respectability, and outcome. Ann Surg Oncol. 1999;6:682–91.CrossRefPubMed
30.
Zurück zum Zitat Talamini MA, Pitt HA, Hruban RH, et al. Spectrum of cystic tumors of the pancreas. Am J Surg. 1992;163:117–24.CrossRefPubMed Talamini MA, Pitt HA, Hruban RH, et al. Spectrum of cystic tumors of the pancreas. Am J Surg. 1992;163:117–24.CrossRefPubMed
31.
Zurück zum Zitat Warshaw AL, Compton CC, Lewandrowski K, et al. Cystic tumors of the pancreas. New clinical, radiologic and pathologic observations in 67 patients. Ann Surg. 1990;212:432–45.CrossRefPubMed Warshaw AL, Compton CC, Lewandrowski K, et al. Cystic tumors of the pancreas. New clinical, radiologic and pathologic observations in 67 patients. Ann Surg. 1990;212:432–45.CrossRefPubMed
32.
Zurück zum Zitat Compton CC. Serous cystic tumors of the pancreas. Semin Diagn Pathol. 2000;17:43–55.PubMed Compton CC. Serous cystic tumors of the pancreas. Semin Diagn Pathol. 2000;17:43–55.PubMed
33.
Zurück zum Zitat Goh BK, Tan YM, Kumarasinghe MP, Ooi LL. Synchronous serous cystadenoma and pancreatic endocrine tumor: a case report and literature review. Dig Dis Sci. 2006;51:422–6.CrossRefPubMed Goh BK, Tan YM, Kumarasinghe MP, Ooi LL. Synchronous serous cystadenoma and pancreatic endocrine tumor: a case report and literature review. Dig Dis Sci. 2006;51:422–6.CrossRefPubMed
34.
Zurück zum Zitat Goh BK, Loh HL, Soo KC. Synchronous pancreatic serous cystic tumor, intraductal papillary tumor and gastric carcinoma: report of a case. Pancreas. 2005;31:195–7.CrossRefPubMed Goh BK, Loh HL, Soo KC. Synchronous pancreatic serous cystic tumor, intraductal papillary tumor and gastric carcinoma: report of a case. Pancreas. 2005;31:195–7.CrossRefPubMed
35.
Zurück zum Zitat Steinberg GD, Bales GT, Brendler CB. An analysis of watchful waiting for clinically localized prostate cancer. J Urology. 1998;159:1431–6.CrossRef Steinberg GD, Bales GT, Brendler CB. An analysis of watchful waiting for clinically localized prostate cancer. J Urology. 1998;159:1431–6.CrossRef
36.
Zurück zum Zitat Schwerk WB. Ultrasonically guided percutaneous puncture and analysis of aspirated material of cystic pancreatic lesions. Digestion. 1981;21:184–92.CrossRefPubMed Schwerk WB. Ultrasonically guided percutaneous puncture and analysis of aspirated material of cystic pancreatic lesions. Digestion. 1981;21:184–92.CrossRefPubMed
37.
Zurück zum Zitat Mou YP et al. Laparoscopic resection of true pancreatic cyst: report of 5 cases. Zhonghua Yi Xue Za Zhi. 2005;85(3):164–5. Chinese.PubMed Mou YP et al. Laparoscopic resection of true pancreatic cyst: report of 5 cases. Zhonghua Yi Xue Za Zhi. 2005;85(3):164–5. Chinese.PubMed
38.
Zurück zum Zitat Cioffi U, Simoni M, Santambrogio R, Fortis D, Ferrino S, Ciulla MM, et al. Laparoscopic enucleation of solitary true pancreatic cyst in an adult. J Gastrointestinal Surg. 2003;7(7):921–4.CrossRef Cioffi U, Simoni M, Santambrogio R, Fortis D, Ferrino S, Ciulla MM, et al. Laparoscopic enucleation of solitary true pancreatic cyst in an adult. J Gastrointestinal Surg. 2003;7(7):921–4.CrossRef
39.
Zurück zum Zitat Carboni F, Mancini P, Lorusso R, Santoro E. Solitary true cyst of the pancreas in adults. A report of two cases JOP. J Pancreas (Online). 2009;10(4):429–31. Carboni F, Mancini P, Lorusso R, Santoro E. Solitary true cyst of the pancreas in adults. A report of two cases JOP. J Pancreas (Online). 2009;10(4):429–31.
40.
Zurück zum Zitat Heindryckx E, Van Steenbergen W, Van Hoe L, Vanbeckevoort D, Ectors N, Baert AL. Solitary true cyst of the pancreas. Eur Radiol. 1998;8(9):1627–9. Heindryckx E, Van Steenbergen W, Van Hoe L, Vanbeckevoort D, Ectors N, Baert AL. Solitary true cyst of the pancreas. Eur Radiol. 1998;8(9):1627–9.
41.
Zurück zum Zitat Fiamingo P, Veroux M, Gringeri E, Mencarelli R, Veroux P, Madia C, D'Amico DF. True solitary pancreatic cyst in an adult: report of a case. Surg Today. 2005;35(11):979–83. Fiamingo P, Veroux M, Gringeri E, Mencarelli R, Veroux P, Madia C, D'Amico DF. True solitary pancreatic cyst in an adult: report of a case. Surg Today. 2005;35(11):979–83.
42.
Zurück zum Zitat Goh BK, Tan YM, Cheow PC, Chung AY, Chow PK, Wong WK, Ooi LL. Solid pseudopapillary neoplasms of the pancreas: an updated experience. J Surg Oncol. 2007;95(8):640–4. Goh BK, Tan YM, Cheow PC, Chung AY, Chow PK, Wong WK, Ooi LL. Solid pseudopapillary neoplasms of the pancreas: an updated experience. J Surg Oncol. 2007;95(8):640–4.
Metadaten
Titel
Solitary True Cyst of Pancreas: Report of a Case and Review of Literature
verfasst von
Mohammad Atif Khan
G. R. Verma
Publikationsdatum
01.06.2010
Verlag
Springer US
Erschienen in
Journal of Gastrointestinal Cancer / Ausgabe 2/2010
Print ISSN: 1941-6628
Elektronische ISSN: 1941-6636
DOI
https://doi.org/10.1007/s12029-010-9139-y

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