Ausgabe 1/2021
Inhalt (14 Artikel)
Artemisinin-type drugs for the treatment of hematological malignancies
R. I. Mancuso, M. A. Foglio, S. T. Olalla Saad
Starting dose selection and dose escalation for oncology small molecule first-in-patient trials: learnings from a survey of FDA-approved drugs
Rajendar K. Mittapalli, Donghua Yin, Darrin Beaupre, Rameshraja Palaparthy
Plasma deoxyuridine as a surrogate marker for toxicity and early clinical response in patients with metastatic colorectal cancer after 5-FU-based therapy in combination with arfolitixorin
Helena Taflin, Elisabeth Odin, Göran Carlsson, Roger Tell, Bengt Gustavsson, Yvonne Wettergren
An investigation into possible interactions among four vascular epidermal growth factor receptor-tyrosine kinase inhibitors with gefitinib
Chenxiang Wang, Lili Ying, Mi Jin, Fangfang Zhang, Dawei Shi, Ying Dai, Ziye Zhou
Dose exploration results from Phase 1 study of cemiplimab, a human monoclonal programmed death (PD)-1 antibody, in Japanese patients with advanced malignancies
Shigehisa Kitano, Toshio Shimizu, Takafumi Koyama, Takahiro Ebata, Satoru Iwasa, Shunsuke Kondo, Akihiko Shimomura, Yutaka Fujiwara, Noboru Yamamoto, Anne Paccaly, Siyu Li, Petra Rietschel, Tasha Sims
Phase 1 study of Gemcitabine/Nab-paclitaxel/S-1 in patients with unresectable pancreatic cancer (GeNeS1S trial)
Satoshi Sai, Masanori Toyoda, Kazutoshi Tobimatsu, Hironaga Satake, Hisateru Yasui, Shiro Kimbara, Taiji Koyama, Yoshimi Fujishima, Yoshinori Imamura, Yohei Funakoshi, Naomi Kiyota, Hirochika Toyama, Yuzo Kodama, Hironobu Minami
Analysis of pharmacogenomic factors for chemotherapy-induced nausea and vomiting in patients with breast cancer receiving doxorubicin and cyclophosphamide chemotherapy
Daiki Tsuji, Megumi Matsumoto, Yohei Kawasaki, Yong-I. L. Kim, Keisuke Yamamoto, Hidenori Nakamichi, Yuri Sahara, Ryo Makuta, Mari Yokoi, Takehiro Miyagi, Kunihiko Itoh
Galeterone sensitizes breast cancer to chemotherapy via targeting MNK/eIF4E and β-catenin
Yulin Xu, Shichong Liao, Lijun Wang, Yuan Wang, Wen Wei, Ke Su, Yi Tu, Shan Zhu
Exploring chemotherapy holiday and drugs re-challenge in advanced pancreatic cancer patients
Marina Macchini, Umberto Peretti, Giulia Orsi, Silvia Zanon, Elena Mazza, Maria Maddalena Valente, Domenico Tamburrino, Giulio Belfiori, Gemma Rossi, Sabrina Gloria Giulia Testoni, Paolo Passoni, Claudio Doglioni, Stefano Cascinu, Michele Reni
HSD3B1 variant and androgen-deprivation therapy outcome in prostate cancer
Fei-fei Han, Lu-lu Ren, Ling-ling Xuan, Ya-li LV, He Liu, Li-li Gong, Zhuo-ling An, Li-hong Liu
Effect of lurbinectedin on the QTc interval in patients with advanced solid tumors: an exposure–response analysis
Salvador Fudio, Josep Tabernero, Vivek Subbiah, Sant P. Chawla, Victor Moreno, Federico Longo, Rafael Lopez, Antonio Anton, Jose Manuel Trigo, Geoffrey Shapiro, Woondong Jeong, Victor Manuel Villalobos, Rubin Lubomirov, Carlos Fernandez-Teruel, Vicente Alfaro, Valentina Boni
MiniPDX-guided postoperative anticancer treatment can effectively prolong the survival of patients with hepatocellular carcinoma
Long Yang, Zheyue Yuan, Yamin Zhang, Zilin Cui, Yang Li, Jiancun Hou, Xiaolong Liu, Zirong Liu, Rui Shi, Qing Tian, Jian Wang, Lianjiang Wang
A Phase Ib multicenter, dose-escalation study of the polyamine analogue PG-11047 in combination with gemcitabine, docetaxel, bevacizumab, erlotinib, cisplatin, 5-fluorouracil, or sunitinib in patients with advanced solid tumors or lymphoma
Tracy Murray Stewart, Daniel Von Hoff, Michael Fitzgerald, Laurence J. Marton, Carlos H. Roberto Becerra, Thomas E. Boyd, Paul R. Conkling, Lawrence E. Garbo, Robert M. Jotte, Donald A. Richards, David A. Smith, Joe J. Stephenson Jr., Nicholas J. Vogelzang, Hillary H. Wu, Robert A. Casero Jr.
Correction to: Successful management of hyperammonemia with hemodialysis on day 2 during 5‑fluorouracil treatment in a patient with gastric cancer: a case report with 5‑fluorouracil metabolite analyses
Yoshinao Ozaki, Hirotaka Imamaki, Aki Ikeda, Mitsuaki Oura, Shunsaku Nakagawa, Taro Funakoshi, Shigeki Kataoka, Yoshitaka Nishikawa, Takahiro Horimatsu, Atsushi Yonezawa, Takeshi Matsubara, Motoko Yanagita, Manabu Muto, Norihiko Watanabe