Ausgabe 4/2012
Inhalt (16 Artikel)
Saccharomyces cerevisiae as a model system to study the response to anticancer agents
Renata Matuo, Fabrício G. Sousa, Daniele G. Soares, Diego Bonatto, Jenifer Saffi, Alexandre E. Escargueil, Annette K. Larsen, João Antonio Pêgas Henriques
A phase 1 study of vinflunine in combination with trastuzumab for the treatment for HER2-positive metastatic breast cancer
R. Paridaens, O. Rixe, M. C. Pinel, H. Wildiers, G. Zorza, P. Ferré, H. Roche
Characterizing the disposition, metabolism, and excretion of an orally active pan-deacetylase inhibitor, panobinostat, via trace radiolabeled 14C material in advanced cancer patients
Sally Clive, Margaret M. Woo, Thomas Nydam, Lindsay Kelly, Margaret Squier, Mark Kagan
Safety and feasibility of adjuvant chemotherapy with S-1 for Korean patients with curatively resected advanced gastric cancer
Jae Ho Jeong, Min-Hee Ryu, Baek-Yeol Ryoo, Sung Sook Lee, Inkeun Park, Sang Hong Lee, Kab Choong Kim, Jeong Hwan Yook, Sung Tae Oh, Byung Sik Kim, Yoon-Koo Kang
A phase II study of docetaxel plus nedaplatin in patients with metastatic non-small-cell lung cancer
Koji Teramoto, Yoshikuni Asada, Yoshitomo Ozaki, Yuji Suzumura, Yasutaka Nakano, Satoru Sawai, Noriaki Tezuka, Shuhei Inoue, Shozo Fujino
The efficacy and toxicity of S-1 and cisplatin as first-line chemotherapy in recurrent or metastatic head and neck squamous cell carcinoma
Han Sang Kim, Hye Ryun Kim, Gun Min Kim, Hyo Song Kim, Yoon Woo Koh, Se Hun Kim, Eun Chang Choi, Yun Kyoung Hong, Ji Hee Sung, Sun Mi Kim, Joo Hang Kim, Byoung Chul Cho
Phase I trial of sunitinib and gemcitabine in patients with advanced solid tumors
Joanna M. Brell, Smitha S. Krishnamurthi, Linda Rath, Joseph A. Bokar, Panayiotis Savvides, Joseph Gibbons, Matthew M. Cooney, Neal J. Meropol, Percy Ivy, Afshin Dowlati
The relationship between Helicobacter pylori infection and the effects of chemotherapy in patients with advanced or metastatic gastric cancer
In Keun Choi, Hwa Jung Sung, Ju-Han Lee, Jun Suk Kim, Jae Hong Seo
A phase I study of BMS-690514 in Japanese patients with advanced or metastatic solid tumors
Hiroshi Nokihara, Noboru Yamamoto, Yasuhide Yamada, Kazuhiko Yamada, Taizo Hirata, Yasushi Goto, Maki Tanioka, Yoko Ikeda, Tomohide Tamura
A single supratherapeutic dose of ridaforolimus does not prolong the QTc interval in patients with advanced cancer
Richard M. Lush, Amita Patnaik, Daniel Sullivan, Kyriakos P. Papadopoulos, Michele Trucksis, Jacqueline McCrea, Kristine Cerchio, Xiaodong Li, Mark Stroh, Diana Selverian, Keith Orford, Scot Ebbinghaus, Nancy Agrawal, Marian Iwamoto, John A. Wagner, Anthony Tolcher
The efficacy and safety of bevacizumab beyond first progression in patients treated with first-line mFOLFOX6 followed by second-line FOLFIRI in advanced colorectal cancer: a multicenter, single-arm, phase II trial (CCOG-0801)
Goro Nakayama, Keisuke Uehara, Kiyoshi Ishigure, Hiroyuki Yokoyama, Akiharu Ishiyama, Takehiko Eguchi, Kenji Tsuboi, Norifumi Ohashi, Tsutomu Fujii, Hiroyuki Sugimoto, Masahiko Koike, Michitaka Fujiwara, Yuich Ando, Yasuhiro Kodera
A phase II trial of ixabepilone in Asian patients with advanced gastric cancer previously treated with fluoropyrimidine-based chemotherapy
Yeul Hong Kim, Kei Muro, Hirofumi Yasui, Jen-Shi Chen, Min-Hee Ryu, Se-Hoon Park, Kent-Man Chu, Su-Pin Choo, Teresa Sanchez, Christine DelaCruz, Pralay Mukhopadhyay, Ioannis Lainas, Chung-Pin Li
A population pharmacokinetic/pharmacodynamic model of thrombocytopenia characterizing the effect of trastuzumab emtansine (T-DM1) on platelet counts in patients with HER2-positive metastatic breast cancer
Brendan C. Bender, Franziska Schaedeli-Stark, Reinhold Koch, Amita Joshi, Yu-Waye Chu, Hope Rugo, Ian E. Krop, Sandhya Girish, Lena E. Friberg, Manish Gupta
Protracted low dose of oral vinorelbine and temozolomide with whole-brain radiotherapy in the treatment for breast cancer patients with brain metastases
Raffaele Addeo, Pasquale Sperlongano, Liliana Montella, Bruno Vincenzi, Marco Carraturo, Patrizia Iodice, Paola Russo, Ciro Parlato, Antonio Salzano, Gregorio Cennamo, Angela Lombardi, Rossella Sperlongano, Salvatore Del Prete, Michele Caraglia
Open-label, single-arm phase II study of pemetrexed in the treatment of patients with recurrent or metastatic nasopharyngeal carcinoma who have had prior platinum-based chemotherapy
Yang Zhang, Liping Zhao, Peiyu Huang, Jingxun Wu, Fenghua Wang, Yan Huang, Li Zhang
Single-dose pharmacokinetic and toxicity analysis of pyrrole–imidazole polyamides in mice
Timothy W. Synold, Bixin Xi, Jun Wu, Yun Yen, Benjamin C. Li, Fei Yang, John W. Phillips, Nicholas G. Nickols, Peter B. Dervan