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Cancer Chemotherapy and Pharmacology

Ausgabe 5/2007

Inhalt (16 Artikel)

Original Article

Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models

Yong S. Chang, Jalila Adnane, Pamela A. Trail, Joan Levy, Arris Henderson, Dahai Xue, Elizabeth Bortolon, Marina Ichetovkin, Charles Chen, Angela McNabola, Dean Wilkie, Christopher A. Carter, Ian C. A. Taylor, Mark Lynch, Scott Wilhelm

Original Article

Pharmacokinetics of low-dose nedaplatin and validation of AUC prediction in patients with non-small-cell lung carcinoma

Takenori Niioka, Tsukasa Uno, Norio Yasui-Furukori, Takenori Takahata, Mikiko Shimizu, Kazunobu Sugawara, Tomonori Tateishi

Original Article

Phase I study of weekly DN-101, a new formulation of calcitriol, in patients with cancer

Tomasz M. Beer, Milind M. Javle, Christopher W. Ryan, Mark Garzotto, Gilbert N. Lam, Alvin Wong, W. David Henner, Candace S. Johnson, Donald L. Trump

Original Article

In vitro anti-cancer activity and structure–activity relationships of natural products isolated from fruits of Panax ginseng

Wei Wang, Yuqing Zhao, Elizabeth R. Rayburn, Donald L. Hill, Hui Wang, Ruiwen Zhang

Original Article

Role of nitric oxide on pathogenesis of 5-fluorouracil induced experimental oral mucositis in hamster

R. F. C. Leitão, R. A. Ribeiro, E. A. L. Bellaguarda, F. D. B. Macedo, L. R. Silva, R. B. Oriá, M. L. Vale, F. Q. Cunha, G. A. C. Brito

Original Article

Chronomodulated administration of oxaliplatin plus capecitabine (XELOX) as first line chemotherapy in advanced colorectal cancer patients: phase II study

Daniele Santini, Bruno Vincenzi, Gaia Schiavon, Marisa Di Seri, Vladimir Virzí, Bruno Spalletta, Marco Caricato, Roberto Coppola, Giuseppe Tonini

Original Article

Gemcitabine and vinorelbine in recurrent advanced non-small cell lung cancer: sequence does matter

Rosalyn Juergens, Julie Brahmer, David Ettinger

Original Article

A phase I study of paclitaxel, cisplatin, and fluorouracil (TCF) for advanced gastric cancer

Takuo Hara, Kenji Omura, Makoto Hirano, Yasuyuki Asada, Yoshinori Munemoto, Junichi Sakamoto

Original Article

Are capecitabine and oxaliplatin (XELOX) suitable treatments for progressing low-grade and high-grade neuroendocrine tumours?

Emilio Bajetta, Laura Catena, Giuseppe Procopio, Sara De Dosso, Ettore Bichisao, Leonardo Ferrari, Antonia Martinetti, Marco Platania, Elena Verzoni, Barbara Formisano, Roberto Bajetta

Original Article

Histological changes in bladders of patients submitted to ifosfamide chemotherapy even with mesna prophylaxis

Marcos Venício Alves Lima, Francisco Valdeci Ferreira, Francisco Yuri Bulcão Macedo, Gerly Anne de Castro Brito, Ronaldo Albuquerque Ribeiro

Original Article

Antitumor activity of HER1/EGFR tyrosine kinase inhibitor erlotinib, alone and in combination with CPT-11 (irinotecan) in human colorectal cancer xenograft models

Jianping Chen, Melissa Smith, Kenneth Kolinsky, Violeta Adames, Nila Mehta, Luke Fritzky, Mohammad Rashed, Eric Wheeldon, Michael Linn, Brian Higgins

Original Article

Antitumour action of 5,6-dimethylxanthenone-4-acetic acid in rats bearing chemically induced primary mammary tumours

Johnson J. Liu, Lai-Ming Ching, Michael Goldthorpe, Rachel Sutherland, Bruce C. Baguley, James A. Kirker, Mark J. McKeage

Clinical Trial Report

Pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid (AS1404), a novel vascular disrupting agent, in phase I clinical trial

M. B. Jameson, B. C. Baguley, P. Kestell, L. Zhao, J. W. Paxton, P. I. Thompson, S. Waller

Clinical Trial Report

Phase I dose-escalation study of a novel antitumor agent, SR271425, administered intravenously in split doses (d1–d2–d3) in patients with refractory solid tumors

M. Campone, N. Isambert, E. Bourbouloux, S. Maury, P. Monin-Baroille, J. Berille, P. Fumoleau

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