Introduction
Patients and methods
Patients
Data and outcomes
Statistical analysis
Definitions
Results
Stability over time
Baseline patient characteristics
Variable | Low NLR (N = 280) | High NLR(N = 278) | p-Value |
---|---|---|---|
Age | 64.7 ± 11.5 | 68.4 ± 11.4 | 0.0001 |
Gender- Female | 101 (36.1) | 84 (30.2) | 0.1508 |
Race | 0.0033 | ||
Caucasian | 230 (82.1) | 255 (91.7) | |
African American | 20 (7.1) | 5 (1.8) | |
Asian | 7 (2.5) | 4 (1.4) | |
Others | 23 (8.2) | 14 (5) | |
BMI | 29.0 ± 5.3 | 29.6 ± 6.7 | 0.2764 |
Diabetes | 0.1713 | ||
Non-insulin dependent | 62 (22.1) | 68 (24.5) | |
Insulin-dependent | 20 (7.1) | 31 (11.2) | |
Dyslipidemia | 219 (78.2) | 225 (80.9) | 0.4629 |
eGFR (ml/min/1.73 m*2) | 88.7 ± 28.9 | 79.7 ± 29.1 | 0.0003 |
Preoperative dialysis | 1 (.4) | 6 (2.2) | 0.0679 |
Hypertension | 232 (82.9) | 233 (83.8) | 0.8205 |
History of endocarditis | 5 (1.8) | 5 (1.8) | 0.9909 |
Chronic lung disease | 5 (1.8) | 10 (3.6) | 0.2027 |
Peripheral vascular disease | 22 (7.9) | 29 (10.4) | 0.2913 |
History of stroke | 15 (5.4) | 14 (5) | 0.8643 |
Prior myocardial infarction | 69 (24.6) | 84 (30.2) | 0.1401 |
Redo sternotomy | 16 (5.7) | 32 (11.5) | 0.0146 |
CHF | 60 (21.4) | 94 (33.8) | 0.0011 |
Variable | Low NLR (N = 280) | High NLR (N = 278) | p-value |
---|---|---|---|
Operative Data | |||
Isolated CABG | 102 (36.4) | 78 (28.1) | 0.0344 |
AVR | 98 (35.0) | 119 (42.8) | 0.0586 |
MVR | 87 (31.1) | 93 (33.5) | 0.5473 |
TVR | 9 (3.2) | 11 (4.0) | 0.6371 |
CPB time (min) | 101.3 ± 36.9 | 110.6 ± 39.3 | 0.0058 |
Leukocyte-related values | |||
Lymphocyte | 2.21 ± 0.63 | 1.50 ± 0.51 | <.0001 |
Neutrophil | 3.79 ± 1.14 | 5.38 ± 1.82 | <.0001 |
NLR | 1.76 ± 0.43 | 3.83 ± 1.60 | <.0001 |
LNR | 0.62 ± 0.21 | 0.29 ± 0.08 | <.0001 |
Complications
Variable | Low NLR (N = 280) | High NLR (N = 278) | p-Value |
---|---|---|---|
Reoperation for bleeding | 2 (0.7) | 6 (2.2) | 0.1754 |
Stroke | 2 (0.7) | 1 (0.4) | 1.0000 |
Prolonged ventilation | 7 (2.5) | 14 (5.0) | 0.1155 |
Pneumonia | 8 (2.9) | 10 (3.6) | 0.6208 |
ICU Length of stay | 2.98 ± 1.70 | 3.38 ± 2.05 | 0.0127 |
In-hospital mortality | 0 (0) | 0 (0) | – |
Any complications or death | 14 (5.0) | 24 (8.6) | 0.0885 |