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Erschienen in: Cardiovascular Intervention and Therapeutics 1/2012

01.01.2012 | Case Report

Staged interventional management of a massive thrombus related to coronary artery ectasia in acute coronary syndrome

verfasst von: Makoto Furugen, Yoshitoki Takagawa

Erschienen in: Cardiovascular Intervention and Therapeutics | Ausgabe 1/2012

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Abstract

Coronary artery ectasia (CAE), which is reported in 0.3–5.3% of coronary angiograms, is known as a risk factor of acute coronary syndrome (ACS). Optimal treatment of CAE in ACS has not yet been established because of few clinical reports and no randomized trial. We describe a 78-year-old woman in whom thrombolysis with recombinant tissue-plasminogen activator, heparin and dual antiplatelet therapy were performed, and an angiogram after 3 days revealed the disappearance of massive thrombus in the CAE of the left circumflex coronary artery. Staged percutaneous coronary intervention and multidisciplinary procedure are feasible to treat ACS with massive thrombus.
Literatur
1.
Zurück zum Zitat Swaye PS, Fisher LD, Litwin P, Vignola PA, Judkins MP, Kemp HG, et al. Aneurysmal coronary artery disease. Circulation. 1983;67(1):134–8.PubMedCrossRef Swaye PS, Fisher LD, Litwin P, Vignola PA, Judkins MP, Kemp HG, et al. Aneurysmal coronary artery disease. Circulation. 1983;67(1):134–8.PubMedCrossRef
2.
Zurück zum Zitat Hartnell GG, Parnell BM, Pridie RB. Coronary artery ectasia. Its prevalence and clinical significance in 4993 patients. Br Heart J. 1985;54(4):392–5.PubMedCrossRef Hartnell GG, Parnell BM, Pridie RB. Coronary artery ectasia. Its prevalence and clinical significance in 4993 patients. Br Heart J. 1985;54(4):392–5.PubMedCrossRef
3.
Zurück zum Zitat Mavrogeni S. Coronary artery ectasia: from diagnosis to treatment. Hellenic J Cardiol. 2010;51(2):158–163. Mavrogeni S. Coronary artery ectasia: from diagnosis to treatment. Hellenic J Cardiol. 2010;51(2):158–163.
4.
Zurück zum Zitat Swanton RH, Thomas ML, Coltart DJ, Jenkins BS, Webb-Peploe MM, Williams BT. Coronary artery ectasia—a variant of occlusive coronary arteriosclerosis. Br Heart J. 1978;40(4):393–400.PubMedCrossRef Swanton RH, Thomas ML, Coltart DJ, Jenkins BS, Webb-Peploe MM, Williams BT. Coronary artery ectasia—a variant of occlusive coronary arteriosclerosis. Br Heart J. 1978;40(4):393–400.PubMedCrossRef
5.
Zurück zum Zitat Hiraishi S, Yashiro K, Oguchi K, Kusano S, Ishii K, Nakazawa K. Clinical course of cardiovascular involvement in the mucocutaneous lymph node syndrome. Relation between clinical signs of carditis and development of coronary arterial aneurysm. Am J Cardiol. 1981;47(2):323–30.PubMedCrossRef Hiraishi S, Yashiro K, Oguchi K, Kusano S, Ishii K, Nakazawa K. Clinical course of cardiovascular involvement in the mucocutaneous lymph node syndrome. Relation between clinical signs of carditis and development of coronary arterial aneurysm. Am J Cardiol. 1981;47(2):323–30.PubMedCrossRef
6.
Zurück zum Zitat Davidson A, Eshaghpour E, Young N, Mintz GS. Late thrombosis of a coronary artery mycotic aneurysm. Am Heart J. 1991;121(5):1549–50.PubMedCrossRef Davidson A, Eshaghpour E, Young N, Mintz GS. Late thrombosis of a coronary artery mycotic aneurysm. Am Heart J. 1991;121(5):1549–50.PubMedCrossRef
7.
Zurück zum Zitat Imahori S, Bannerman RM, Graf CJ, Brennan JC. Ehlers–Danlos syndrome with multiple arterial lesions. Am J Med. 1969;47(6):967–77.PubMedCrossRef Imahori S, Bannerman RM, Graf CJ, Brennan JC. Ehlers–Danlos syndrome with multiple arterial lesions. Am J Med. 1969;47(6):967–77.PubMedCrossRef
8.
Zurück zum Zitat Matayoshi AH, Dhond MR, Laslett LJ. Multiple coronary aneurysms in a case of systemic lupus erythematosus. Chest. 1999;116(4):1116–8.PubMedCrossRef Matayoshi AH, Dhond MR, Laslett LJ. Multiple coronary aneurysms in a case of systemic lupus erythematosus. Chest. 1999;116(4):1116–8.PubMedCrossRef
9.
Zurück zum Zitat Tang PH, Segal AJ. Polyarteritis nodosa of infancy. Fatal late complication. JAMA. 1971;217(12):1666–70.PubMedCrossRef Tang PH, Segal AJ. Polyarteritis nodosa of infancy. Fatal late complication. JAMA. 1971;217(12):1666–70.PubMedCrossRef
10.
Zurück zum Zitat Chaithiraphan S, Goldberg E, O’Reilly M, Jootar P. Multiple aneurysms of coronary artery in sclerodermal heart disease. Angiology. 1973;24(2):86–93.PubMedCrossRef Chaithiraphan S, Goldberg E, O’Reilly M, Jootar P. Multiple aneurysms of coronary artery in sclerodermal heart disease. Angiology. 1973;24(2):86–93.PubMedCrossRef
11.
Zurück zum Zitat Binstadt BA, Levine JC, Nigrovic PA, Gauvreau K, Dedeoglu F, Fuhlbrigge RC, et al. Coronary artery dilation among patients presenting with systemic-onset juvenile idiopathic arthritis. Pediatrics. 2005;116(1):e89–93.PubMedCrossRef Binstadt BA, Levine JC, Nigrovic PA, Gauvreau K, Dedeoglu F, Fuhlbrigge RC, et al. Coronary artery dilation among patients presenting with systemic-onset juvenile idiopathic arthritis. Pediatrics. 2005;116(1):e89–93.PubMedCrossRef
12.
Zurück zum Zitat Noma M, Kikuchi Y, Yoshimura H, Yamamoto H, Tajimi T. Coronary ectasia in Takayasu’s arteritis. Am Heart J. 1993;126(2):459–61.PubMedCrossRef Noma M, Kikuchi Y, Yoshimura H, Yamamoto H, Tajimi T. Coronary ectasia in Takayasu’s arteritis. Am Heart J. 1993;126(2):459–61.PubMedCrossRef
13.
Zurück zum Zitat Gardiner DS, Lindop GB. Coronary artery aneurysm due to primary cardiac lymphoma. Histopathology. 1989;15(5):537–40.PubMedCrossRef Gardiner DS, Lindop GB. Coronary artery aneurysm due to primary cardiac lymphoma. Histopathology. 1989;15(5):537–40.PubMedCrossRef
14.
Zurück zum Zitat Satran A, Bart BA, Henry CR, Murad MB, Talukdar S, Satran D, et al. Increased prevalence of coronary artery aneurysms among cocaine users. Circulation. 2005;111(19):2424–9.PubMedCrossRef Satran A, Bart BA, Henry CR, Murad MB, Talukdar S, Satran D, et al. Increased prevalence of coronary artery aneurysms among cocaine users. Circulation. 2005;111(19):2424–9.PubMedCrossRef
15.
Zurück zum Zitat Nichols L, Lagana S, Parwani A. Coronary artery aneurysm: a review and hypothesis regarding etiology. Arch Pathol Lab Med. 2008;132(5):823–8.PubMed Nichols L, Lagana S, Parwani A. Coronary artery aneurysm: a review and hypothesis regarding etiology. Arch Pathol Lab Med. 2008;132(5):823–8.PubMed
16.
Zurück zum Zitat Daoud AS, Pankin D, Tulgan H, Florentin RA. Aneurysms of the coronary artery. Report of ten cases and review of literature. Am J Cardiol. 1963;11:228–37.PubMedCrossRef Daoud AS, Pankin D, Tulgan H, Florentin RA. Aneurysms of the coronary artery. Report of ten cases and review of literature. Am J Cardiol. 1963;11:228–37.PubMedCrossRef
17.
Zurück zum Zitat Virmani R, Robinowitz M, Atkinson JB, Forman MB, Silver MD, McAllister HA. Acquired coronary arterial aneurysms: an autopsy study of 52 patients. Hum Pathol. 1986;17(6):575–83.PubMedCrossRef Virmani R, Robinowitz M, Atkinson JB, Forman MB, Silver MD, McAllister HA. Acquired coronary arterial aneurysms: an autopsy study of 52 patients. Hum Pathol. 1986;17(6):575–83.PubMedCrossRef
18.
Zurück zum Zitat Henriques JP, Zijlstra F, Ottervanger JP, de Boer MJ, van’t Hof AW, Hoorntje JC, et al. Incidence and clinical significance of distal embolization during primary angioplasty for acute myocardial infarction. Eur Heart J. 2002;23(14):1112–7.PubMedCrossRef Henriques JP, Zijlstra F, Ottervanger JP, de Boer MJ, van’t Hof AW, Hoorntje JC, et al. Incidence and clinical significance of distal embolization during primary angioplasty for acute myocardial infarction. Eur Heart J. 2002;23(14):1112–7.PubMedCrossRef
19.
Zurück zum Zitat Cuisset T, Hamilos M, Melikian N, Wyffels E, Sarma J, Sarno G, et al. Direct stenting for stable angina pectoris is associated with reduced periprocedural microcirculatory injury compared with stenting after pre-dilation. J Am Coll Cardiol. 2008;51(11):1060–5.PubMedCrossRef Cuisset T, Hamilos M, Melikian N, Wyffels E, Sarma J, Sarno G, et al. Direct stenting for stable angina pectoris is associated with reduced periprocedural microcirculatory injury compared with stenting after pre-dilation. J Am Coll Cardiol. 2008;51(11):1060–5.PubMedCrossRef
20.
Zurück zum Zitat Cook S, Wenaweser P, Togni M, Billinger M, Morger C, Seiler C, et al. Incomplete stent apposition and very late stent thrombosis after drug-eluting stent implantation. Circulation. 2007;115(18):2426–34.PubMedCrossRef Cook S, Wenaweser P, Togni M, Billinger M, Morger C, Seiler C, et al. Incomplete stent apposition and very late stent thrombosis after drug-eluting stent implantation. Circulation. 2007;115(18):2426–34.PubMedCrossRef
21.
Zurück zum Zitat Giombolini C, Notaristefano S, Santucci S, Notaristefano F, Notaristefano A, Ambrosio G. AngioJet thrombectomy for the treatment of coronary artery aneurysm after failed thrombolysis in acute myocardial infarction. Heart Int. 2006;2(2):94–7.PubMedCrossRef Giombolini C, Notaristefano S, Santucci S, Notaristefano F, Notaristefano A, Ambrosio G. AngioJet thrombectomy for the treatment of coronary artery aneurysm after failed thrombolysis in acute myocardial infarction. Heart Int. 2006;2(2):94–7.PubMedCrossRef
22.
Zurück zum Zitat Svilaas T, Vlaar PJ, van der Horst IC, Diercks GF, de Smet BJ, van den Heuvel AF, et al. Thrombus aspiration during primary percutaneous coronary intervention. N Engl J Med. 2008;358(6):557–67.PubMedCrossRef Svilaas T, Vlaar PJ, van der Horst IC, Diercks GF, de Smet BJ, van den Heuvel AF, et al. Thrombus aspiration during primary percutaneous coronary intervention. N Engl J Med. 2008;358(6):557–67.PubMedCrossRef
23.
Zurück zum Zitat Thanyasiri P, Celermajer DS, Adams MR. Endothelial dysfunction occurs in peripheral circulation patients with acute and stable coronary artery disease. Am J Physiol Heart Circ Physiol. 2005;289(2):H513–7.PubMedCrossRef Thanyasiri P, Celermajer DS, Adams MR. Endothelial dysfunction occurs in peripheral circulation patients with acute and stable coronary artery disease. Am J Physiol Heart Circ Physiol. 2005;289(2):H513–7.PubMedCrossRef
24.
Zurück zum Zitat Hrafnkelsdottir T, Ottosson P, Gudnason T, Samuelsson O, Jern S. Impaired endothelial release of tissue-type plasminogen activator in patients with chronic kidney disease and hypertension. Hypertension. 2004;44(3):300–4.PubMedCrossRef Hrafnkelsdottir T, Ottosson P, Gudnason T, Samuelsson O, Jern S. Impaired endothelial release of tissue-type plasminogen activator in patients with chronic kidney disease and hypertension. Hypertension. 2004;44(3):300–4.PubMedCrossRef
25.
Zurück zum Zitat Newby DE, McLeod AL, Uren NG, Flint L, Ludlam CA, Webb DJ, et al. Impaired coronary tissue plasminogen activator release is associated with coronary atherosclerosis and cigarette smoking: direct link between endothelial dysfunction and atherothrombosis. Circulation. 2001;103(15):1936–41.PubMed Newby DE, McLeod AL, Uren NG, Flint L, Ludlam CA, Webb DJ, et al. Impaired coronary tissue plasminogen activator release is associated with coronary atherosclerosis and cigarette smoking: direct link between endothelial dysfunction and atherothrombosis. Circulation. 2001;103(15):1936–41.PubMed
26.
Zurück zum Zitat Cantor WJ, Fitchett D, Borgundvaag B, Heffernan M, Cohen EA, Morrison LJ, et al. Rationale and design of the Trial of Routine ANgioplasty and Stenting After Fibrinolysis to Enhance Reperfusion in Acute Myocardial Infarction (TRANSFER-AMI). Am Heart J. 2008;155(1):19–25.PubMedCrossRef Cantor WJ, Fitchett D, Borgundvaag B, Heffernan M, Cohen EA, Morrison LJ, et al. Rationale and design of the Trial of Routine ANgioplasty and Stenting After Fibrinolysis to Enhance Reperfusion in Acute Myocardial Infarction (TRANSFER-AMI). Am Heart J. 2008;155(1):19–25.PubMedCrossRef
Metadaten
Titel
Staged interventional management of a massive thrombus related to coronary artery ectasia in acute coronary syndrome
verfasst von
Makoto Furugen
Yoshitoki Takagawa
Publikationsdatum
01.01.2012
Verlag
Springer Japan
Erschienen in
Cardiovascular Intervention and Therapeutics / Ausgabe 1/2012
Print ISSN: 1868-4300
Elektronische ISSN: 1868-4297
DOI
https://doi.org/10.1007/s12928-011-0083-y

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