Erschienen in:
08.03.2017 | Editorial
Starting a Fixed-Dose Combination Pill versus a Single Agent for Patients with Hypertension
verfasst von:
Edward J. Filippone, MD, FACP, Andrew J. Foy, MD
Erschienen in:
Journal of General Internal Medicine
|
Ausgabe 6/2017
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Excerpt
Hypertension remains the number-one cause of morbidity and mortality worldwide,
1 and it is well established that treating elevated blood pressure with antihypertensive medications improves these outcomes.
2 Target blood pressure values have been promulgated by societies in both Europe and the United States, although large surveys indicate that a significant percentage of patients treated for hypertension do not reach these targets.
3 It is now recommended that therapy be initiated with two rather than one medication in individuals with higher pretreatment blood pressure in order to enhance the chances of success.
4 , 5 Overall, the most commonly used classes of antihypertensives (i.e., diuretics, beta blockers [BB], calcium channel blockers [CCB], and renin-angiotensin system inhibitors [RASI]) are approximately equally effective in reducing cardiovascular events and mortality.
2 …
