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International Journal of Hematology
Erschienen in: International Journal of Hematology 5/2015

01.05.2015 | Progress in Hematology

State-of-the-art acute and chronic GVHD treatment

verfasst von: Muhammad Omer Jamil, Shin Mineishi

Erschienen in: International Journal of Hematology | Ausgabe 5/2015

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Abstract

Graft-versus-host disease (GVHD) remains as the major obstacle for successful hematopoietic stem cell transplant (HSCT). Roughly half of the patients undergoing HSCT develop GVHD which requires treatment, and above 10 % of the patient may die because of it. However, GVHD presents with anti-tumor activity, called graft-versus-tumor (GVT) effect, and it carries significant anti-tumor activity, thus suppressing GVHD completely may increase the relapse of original disease. Thus, it is important to control GVHD to the appropriate level.
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Metadaten
Titel
State-of-the-art acute and chronic GVHD treatment
verfasst von
Muhammad Omer Jamil
Shin Mineishi
Publikationsdatum
01.05.2015
Verlag
Springer Japan
Erschienen in
International Journal of Hematology / Ausgabe 5/2015
Print ISSN: 0925-5710
Elektronische ISSN: 1865-3774
DOI
https://doi.org/10.1007/s12185-015-1785-1

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