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Erschienen in: Archives of Gynecology and Obstetrics 6/2019

03.11.2019 | Gynecologic Oncology

Struma ovarii with atypical features and synchronous primary thyroid cancer: a case report and review of the literature

verfasst von: Molly R. Siegel, Rebecca J. Wolsky, Edwin A. Alvarez, Biftu M. Mengesha

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 6/2019

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Abstract

Purpose

To present a case of struma ovarii with a typical features and synchronous primary thyroid carcinoma and review the available literature to guide diagnosis and management of these tumors.

Methods

We present a case from our hospital of a 55-year-old woman who had an adnexal mass with features concerning for papillary thyroid carcinoma and was ultimately determined to be struma ovarii with atypical features. Subsequent thyroid imaging and biopsy revealed a primary cervical thyroid carcinoma. We performed a PubMed search of published English language articles using the search terms “malignant struma ovarii,” “metastatic struma ovarii,” “struma ovarii with malignant transformation,” “struma ovarii papillary thyroid carcinoma,” “struma ovarii follicular thyroid carcinoma,” and “struma ovarii with concurrent primary thyroid carcinoma.”

Results

Literature review included 104 studies with a total of 195 patient cases. The average age at presentation was 44.9 years. 25.1% of patients had metastatic disease at presentation, and 6.2% had synchronous primary carcinomas; all of which were located in the thyroid.

Conclusions

Thyroid carcinoma arising in struma ovarii or mature cystic teratoma should prompt clinical evaluation and imaging of the thyroid given the possibility of synchronous primaries, metastases, and recurrence.
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Metadaten
Titel
Struma ovarii with atypical features and synchronous primary thyroid cancer: a case report and review of the literature
verfasst von
Molly R. Siegel
Rebecca J. Wolsky
Edwin A. Alvarez
Biftu M. Mengesha
Publikationsdatum
03.11.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
Archives of Gynecology and Obstetrics / Ausgabe 6/2019
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-019-05329-z

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