The online version of this article (doi:10.1186/1477-7819-10-93) contains supplementary material, which is available to authorized users.
The authors declare that they have no competing interests.
FS, MW, RC, and PI analyzed the data and wrote the manuscript. DR, AD, and DS participated in the acquisition and interpretation of radiological data. DA carried out the histological and bio-molecular studies. FS and PI contributed to the final version and carried out the clinical case report. All authors read and approved the final manuscript.
Struma ovarii (SO) is a slow-growing ovarian neoplasm with thyroid tissue as its predominant component. It is an uncommon neoplasm, usually asymptomatic with an unknown risk of malignant transformation. Due to difficulties in assessing the rare biological nature and the discrepancies in the reported cases, a consensus on the appropriate treatment has not been definitively reached.
A 50-year-old female was subjected to upper gut endoscopy which showed a 30-mm mass located in the gastric antrum, suggestive of mesenchimal tumor. Incidentally, a pelvic CT scan also documented a solid mass in the right adnexa, with morphological characteristics of ovarian neoplasm. The patient underwent gastrectomy, total hysterectomy, bilateral salpingo-oophorectomy with lymph node dissection, and omentectomy. Histology documented the presence of gastric cavernous angioma, and, in the right adnexa, foci of follicular thyroid-type carcinoma arising in SO with a well-differentiated neuroendocrine component.
Here we report and discuss the clinical and morphological presentation of follicular thyroid-type carcinoma arising in SO. The neoplasm was discovered incidentally and had a favorable clinical outcome at 1-year follow-up.
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- Struma ovarii with follicular thyroid-type carcinoma and neuroendocrine component: case report
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