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Annals of Hematology

Erschienen in:

01.01.2004 | Case Report

Successful labor in the course of chronic lymphocytic leukemia (CLL) and management of CLL during pregnancy with leukapheresis

verfasst von: R. Ali, F. Özkalemkaş, V. Özkocaman, E. Bülbül-Başkan, T. Özçelik, Ü. Ozan, Y. Kimya, A. Tunalı

Erschienen in: Annals of Hematology | Ausgabe 1/2004

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Abstract

We describe the successful management of a 30-year-old woman in the second trimester of her pregnancy with chronic lymphocytic leukemia (CLL) in stage IV by using only leukapheresis. We applied three sessions (courses) of leukapheresis throughout the pregnancy. The procedure did not have any significant adverse effect on the patient and the fetus. The patient gave birth vaginally to a healthy boy, weighing 3100 g, at 39 weeks of gestation. Seven months after delivery, Richter's syndrome developed in the patient. We conclude that leukapheresis may provide an alternative for palliative treatment to chemotherapy in pregnant patients with CLL. To our knowledge, this is the fourth reported case of CLL in pregnancy, and the first management of CLL during pregnancy with leukapheresis.

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Titel: Successful labor in the course of chronic lymphocytic leukemia (CLL) and management of CLL during pregnancy with leukapheresis
verfasst von: R. Ali
F. Özkalemkaş
V. Özkocaman
E. Bülbül-Başkan
T. Özçelik
Ü. Ozan
Y. Kimya
A. Tunalı
Publikationsdatum: 01.01.2004
Verlag: Springer-Verlag
Erschienen in: Annals of Hematology / Ausgabe 1/2004
Print ISSN: 0939-5555
Elektronische ISSN: 1432-0584
DOI: https://doi.org/10.1007/s00277-003-0723-0

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