Erschienen in:
01.09.2013 | Breast Oncology
Supporting Trials for Primary Tumor Resection in Stage IV Breast Cancer is Paramount
verfasst von:
Elly Harris, MD, Mitchel Barry, MD, FRCSI, Malcolm R. Kell, FRCSI
Erschienen in:
Annals of Surgical Oncology
|
Ausgabe 9/2013
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Excerpt
A key motivation behind publishing our meta-analysis to determine whether surgical resection of the primary tumor in the setting of stage IV breast cancer affects survival was to reassure clinicians and their patients that entering patients into the one of the ongoing six randomized trials—or indeed into the prospective registry study led by T. A. King—was safe and would not compromise patient care. Failure to accrue the appropriate number of patients can be detrimental to any randomized trial, and therefore some level of evidence, albeit biased and with recognized limitations, is required to support trial accrual. …