Skip to main content
Hauptrubriken
CME Facharzt-Training Webinare Zeitschriften Bücher e.Medpedia Podcast
Service
Jobbörse Info & Hilfe
Fachgebiete
Anästhesiologie Allgemeinmedizin Arbeitsmedizin Augenheilkunde Chirurgie Dermatologie Gynäkologie und Geburtshilfe HNO Innere Medizin Kardiologie Neurologie Onkologie und Hämatologie Orthopädie und Unfallchirurgie Pädiatrie Pathologie Psychiatrie Radiologie Rechtsmedizin Urologie Zahnmedizin
Themen
Klimawandel und Gesundheit Neues aus dem Markt COVID-19 Praxis und Beruf Seltene Erkrankungen GOÄ & EBM Panorama
Sammlungen
Kasuistiken Algorithmen & Infografiken Blickdiagnosen Arthropedia FlapFinder (für Dermatochirurgen) Videos Kongressberichterstattung Medizin für Apothekerinnen und Apotheker Für Ärztinnen und Ärzte in Weiterbildung Für Medizinstudierende
Erweiterte Suche
Anmelden
nach oben
Surgery Today
Erschienen in: Surgery Today 9/2014

01.09.2014 | Review Article

Surgical strategies for esophageal cancer associated with head and neck cancer

verfasst von: Masaru Morita, Hiroshi Saeki, Shuhei Ito, Yasue Kimura, Nami Yamashita, Koji Ando, Yukiharu Hiyoshi, Eriko Tokunaga, Eiji Oki, Tetsuo Ikeda, Sei Yoshida, Torahiko Nakashima, Yoshihiko Maehara

Erschienen in: Surgery Today | Ausgabe 9/2014

Einloggen, um Zugang zu erhalten

Abstract

Esophageal cancer is frequently associated with squamous cell carcinoma in the head and neck. Both cigarette smoking and alcohol consumption are risk factors for multiple cancers of the head and neck, as well as the esophagus. Routine screening and close follow-up for second cancers are important in patients with esophageal cancer or head and neck cancer. For this purpose, endoscopy with Lugol’s staining, as well as narrow-band imaging combined with magnifying endoscopy, is a powerful tool for the early detection of esophageal cancer. Multimodal therapy is essential for patients with double cancers. When considering surgical treatment, the curability of both cancers must be carefully evaluated. If both tumors are potentially curable, each lesion should be treated individually. In patients with metachronous double cancers, the prior treatment of the first primary carcinoma often affects the treatment of the second cancer. Close cooperation among medical staff members is essential for complicated surgeries for double cancers. Techniques that are appropriate for each case must be adopted, such as careful dissection, staged operations, muscular flaps and microvascular anastomosis.
Literatur
1.
Morita M, Yoshida R, Ikeda K, Egashira A, Oki E, Sadanaga N, et al. Advances in esophageal cancer surgery in Japan: an analysis of 1000 consecutive patients treated at a single institute. Surgery. 2008;143:499–508.PubMedCrossRef
2.
Morita M, Kumashiro R, Kubo N, Nakashima Y, Yoshida R, Yoshinaga K, et al. Alcohol drinking, cigarette smoking, and the development of squamous cell carcinoma of the esophagus: epidemiology, clinical findings, and prevention. Int J Clin Oncol. 2010;15:126–34.PubMed
3.
Kuwano H, Morita M, Matsuda H, Mori M, Sugimachi K. Histopathologic findings of minute foci of squamous cell carcinoma in the human esophagus. Cancer. 1991;68:2617–20.PubMedCrossRef
4.
Morita M, Kuwano H, Yasuda M, Watanabe M, Ohno S, Saito T, et al. The multicentric occurrence of squamous epithelial dysplasia and squamous cell carcinoma in the esophagus. Cancer. 1994;74:2889–95.PubMedCrossRef
5.
Ito S, Ohga T, Saeki H, Nakamura T, Watanabe M, Tanaka S, et al. p53 mutation profiling of multiple esophageal carcinoma using laser capture microdissection to demonstrate field carcinogenesis. Int J Cancer. 2005;113:22–8.PubMed
6.
Kuwano H, Morita M, Tsutsui S, Kido Y, Mori M, Sugimachi K. Comparison of characteristics of esophageal squamous cell carcinoma associated with head and neck cancer and those with gastric cancer. J Surg Oncol. 1991;46:107–9.PubMedCrossRef
7.
Morita M, Kuwano H, Ohno S, Sugimachi K, Seo Y, Tomoda H, et al. Multiple occurrence of carcinoma in the upper aerodigestive tract associated with esophageal cancer: reference to smoking, drinking and family history. Int J Cancer. 1994;58:207–10.PubMed
8.
Morita M, Araki K, Saeki H, Sakaguchi Y, Baba H, Sugimachi K, et al. Risk factors for multicentric occurrence of carcinoma in the upper aerodigestive tract-analysis with a serial histologic evaluation of the whole resected-esophagus including carcinoma. J Surg Oncol. 2003;83:216–21.PubMedCrossRef
9.
Yokoyama A, Muramatsu T, Ohmori T, Makuuchi H, Higuchi S, Matsushita S, et al. Multiple primary esophageal and concurrent upper aerodigestive tract cancer and the aldehyde dehydrogenase-2 genotype of Japanese alcoholics. Cancer. 1996;77:1986–90.PubMedCrossRef
10.
Saeki H, Toh Y, Morita M, Sugiyama M, Morita K, Sakamoto Y, et al. The treatment outcomes of synchronous and metachronous esophageal squamous cell carcinoma and head and neck squamous cell carcinoma. Esophagus. 2012;9:158–64.CrossRef
11.
Morita M, Kawano H, Otsu H, Kimura Y, Saeki H, Ando K, et al. Surgical resection for esophageal cancer synchronously or metachronously associated with head and neck cancer. Ann Surg Oncol. 2013;20:2434–9.PubMedCrossRef
12.
Watanabe M, Baba Y, Nagai Y, Baba H. Minimally invasive esophagectomy for esophageal cancer: an updated review. Surg Today. 2013;43:237–44.PubMedCrossRef
13.
Ozawa S. Comprehensive registry of esophageal canccer in Japan, 2004. In: Ozawa S, editor. Chiba: The Japan Esophageal Society; 2012. p. 8.
14.
Chuang SC, Hashibe M, Scelo G, Brewster DH, Pukkala E, Friis S, et al. Risk of second primary cancer among esophageal cancer patients: a pooled analysis of 13 cancer registries. Cancer Epidemiol Biomarkers Prev. 2008;17:1543–9.PubMedCrossRef
15.
Chuang SC, Scelo G, Tonita JM, Tamaro S, Jonasson JG, Kliewer EV, et al. Risk of second primary cancer among patients with head and neck cancers: a pooled analysis of 13 cancer registries. Int J Cancer. 2008;123:2390–6.PubMed
16.
Matsubara T, Yamada K, Nakagawa A. Risk of second primary malignancy after esophagectomy for squamous cell carcinoma of the thoracic esophagus. J Clin Oncol. 2003;21:4336–41.PubMedCrossRef
17.
Natsugoe S, Uchino Y, Kijima F, Shimada M, Shirao K, Kusano C, et al. Synchronous and metachronous carcinomas of the esophagus and head and neck. Dis Esophagus. 1997;10:134–8.PubMed
18.
Kohmura T, Hasegawa Y, Matsuura H, Terada A, Takahashi M, Nakashima T. Clinical analysis of multiple primary malignancies of the hypopharynx and esophagus. Am J Otolaryngol. 2001;22:107–10.PubMedCrossRef
19.
Weaver A, Fleming SM, Knechtges TC, Smith D. Triple endoscopy: a neglected essential in head and neck cancer. Surgery. 1979;86:493–6.PubMed
20.
Guardiola E, Pivot X, Dassonville O, Poissonnet G, Marcy PY, Otto J, et al. Is routine triple endoscopy for head and neck carcinoma patients necessary in light of a negative chest computed tomography scan? Cancer. 2004;101:2028–33.PubMedCrossRef
21.
Rodriguez-Bruno K, Ali MJ, Wang SJ. Role of panendoscopy to identify synchronous second primary malignancies in patients with oral cavity and oropharyngeal squamous cell carcinoma. Head Neck. 2011;33:949–53.PubMedCrossRef
22.
Sugimachi K, Ohno S, Matsuda H, Mori M, Kuwano H. Lugol-combined endoscopic detection of minute malignant lesions of the thoracic esophagus. Ann Surg. 1988;208:179–83.PubMedCentralPubMedCrossRef
23.
Sugimachi K, Tsutsui S, Kitamura K, Morita M, Mori M, Kuwano H. Lugol stain for intraoperative determination of the proximal surgical margin of the esophagus. J Surg Oncol. 1991;46:226–9.PubMedCrossRef
24.
Schiller W. Early diagnosis of carcinoma of the cervix. Surg Gynecol Obstet. 1933;56:210–22.
25.
Hashimoto CL, Iriya K, Baba ER, Navarro-Rodriguez T, Zerbini MC, Eisig JN, et al. Lugol’s dye spray chromoendoscopy establishes early diagnosis of esophageal cancer in patients with primary head and neck cancer. Am J Gastroenterol. 2005;100:275–82.PubMedCrossRef
26.
Shiozaki H, Tahara H, Kobayashi K, Yano H, Tamura S, Imamoto H, et al. Endoscopic screening of early esophageal cancer with the Lugol dye method in patients with head and neck cancers. Cancer. 1990;66:2068–71.PubMedCrossRef
27.
Shimizu Y, Tukagoshi H, Fujita M, Hosokawa M, Kato M, Asaka M. Metachronous squamous cell carcinoma of the esophagus arising after endoscopic mucosal resection. Gastrointest Endosc. 2001;54:190–4.PubMedCrossRef
28.
Hori K, Okada H, Kawahara Y, Takenaka R, Shimizu S, Ohno Y, et al. Lugol-voiding lesions are an important risk factor for a second primary squamous cell carcinoma in patients with esosphageal cancer or head and neck cancer. Am J Gastroenterol. 2011;106:858–66.PubMedCrossRef
29.
Katada C, Muto M, Nakayama M, Tanabe S, Higuchi K, Sasaki T, et al. Risk of superficial squamous cell carcinoma developing in the head and neck region in patients with esophageal squamous cell carcinoma. Laryngoscope. 2012;122:1291–6.PubMedCrossRef
30.
Muto M, Hironaka S, Nakane M, Boku N, Ohtsu A, Yoshida S. Association of multiple Lugol-voiding lesions with synchronous and metachronous esophageal squamous cell carcinoma in patients with head and neck cancer. Gastrointest Endosc. 2002;56:517–21.PubMedCrossRef
31.
Takenaka R, Kawahara Y, Okada H, Hori K, Inoue M, Kawano S, et al. Narrow-band imaging provides reliable screening for esophageal malignancy in patients with head and neck cancers. Am J Gastroenterol. 2009;104:2942–8.PubMedCrossRef
32.
Nonaka S, Saito Y, Oda I, Kozu T, Saito D. Narrow-band imaging endoscopy with magnification is useful for detecting metachronous superficial pharyngeal cancer in patients with esophageal squamous cell carcinoma. J Gastroenterol Hepatol. 2010;25:264–9.PubMedCrossRef
33.
Muto M, Minashi K, Yano T, Saito Y, Oda I, Nonaka S, et al. Early detection of superficial squamous cell carcinoma in the head and neck region and esophagus by narrow band imaging: a multicenter randomized controlled trial. J Clin Oncol. 2010;28:1566–72.PubMedCentralPubMedCrossRef
34.
Katada C, Tanabe S, Koizumi W, Higuchi K, Sasaki T, Azuma M, et al. Narrow band imaging for detecting superficial squamous cell carcinoma of the head and neck in patients with esophageal squamous cell carcinoma. Endoscopy. 2010;42:185–90.PubMedCrossRef
35.
Tachimori Y, Watanabe H, Kato H, Ebihara S, Ono I, Nakatsuka T, et al. Treatment for synchronous and metachronous carcinomas of the head and neck and esophagus. J Surg Oncol. 1990;45:43–5.PubMedCrossRef
36.
Oki E, Morita M, Kakeji Y, Ikebe M, Sadanaga N, Egasira A, et al. Salvage esophagectomy after definitive chemo radiotherapy for esophageal cancer. Dis Esophagus. 2007;20:301–4.PubMedCrossRef
37.
Tachimori Y, Kanamori N, Uemura N, Hokamura N, Igaki H, Kato H. Salvage esophagectomy after high-dose chemoradiotherapy for esophageal squamous cell carcinoma. J Thorac Cardiovasc Surg. 2009;137:49–54.PubMedCrossRef
38.
Morita M, Kumashiro R, Hisamatsu Y, Nakanishi R, Egashira A, Saeki H, et al. Clinical significance of salvage esophagectomy for remnant or recurrent cancer following definitive chemo radiotherapy. J Gastroenterol. 2011;46:1284–91.PubMedCrossRef
39.
Yoshida R, Morita M, Ando K, Masuda T, Saeki H, Oki E, et al. Salvage esophagectomy after definitive chemo radiotherapy for synchronous double cancers of the esophagus and head-and-neck. Dis Esophagus. 2010;23:59–63.PubMedCrossRef
40.
Wind P, Roullet MH, Quinaux D, Laccoureye O, Brasnu D, Cugnenc PH. Long-term results after esophagectomy for squamous cell carcinoma of the esophagus associated with head and neck cancer. Am J Surg. 1999;178:251–5.PubMedCrossRef
41.
Morita M, Nakanoko T, Kubo N, Fujinaka Y, Ikeda K, Egashira A, et al. Two-stage operation for high-risk patients with thoracic esophageal cancer: an old operation revisited. Ann Surg Oncol. 2011;18:2613–21.PubMedCrossRef
42.
Yoshida R, Morita M, Kumashiro R, Ikeda K, Egashira A, Saeki H, et al. Staged operation for synchronous quintuple cancer in the oral cavity, hypopharynx, and esophagus. Esophagus. 2012;9:228–33.CrossRef
43.
Hisamatsu Y, Morita M, Saeki H, Egashira A, Ohga T, Kakji Y, et al. Staged resection and reconstruction following definitive chemo radiotherapy for perforated cervico-thoracic esophageal cancer with mediastinal abscess. Esophagus. 2011;8:197–201.CrossRef
44.
Lo OS, Law S, Wei WI, Ng WM, Wong KH, Tong KH, et al. Esophageal cancers with synchronous or antecedent head and neck cancers: a more formidable challenge? Ann Surg Oncol. 2008;15:1750–6.PubMedCrossRef
45.
Sun K, Matsubara T, Ueda M. Surgical treatment for primary esophageal cancer developing after pharyngo laryngectomy for head and neck cancer. Surgery. 1997;122:15–9.PubMedCrossRef
46.
Wind P, Roullet MH, Douard R, Laccoureye O, Brasnu D, Cugnenc PH. Experience in the treatment of synchronous and metachronous carcinoma of the oesophagus and the head and neck. J Surg Oncol. 2000;73:138–42.PubMedCrossRef
47.
Cooper JS, Guo MD, Herskovic A, Macdonald JS, Martenson JA Jr, Al-Sarraf M, et al. Chemoradiotherapy of locally advanced esophageal cancer: long-term follow-up of a prospective randomized trial (RTOG 85-01) radiation therapy oncology group. JAMA. 1999;281:1623–7.PubMedCrossRef
48.
Kadota H, Fukushima J, Nakashima T, Kumamoto Y, Yoshida S, Yasumatsu R, et al. Comparison of salvage and planned pharyngolaryngectomy with jejunal transfer for hypopharyngeal carcinoma after chemoradiotherapy. Laryngoscope. 2010;120:1103–8.PubMed
49.
Wong SK, Chan AC, Lee DW, To EW, Ng EK, Chung SC. Minimal invasive approach of gastric and esophageal mobilization in total pharyngo laryngo esophagectomy: total laparoscopic and hand-assisted laparoscopic technique. Surg Endosc. 2003;17:798–802.PubMedCrossRef
50.
Rossi M, Santi S, Barreca M, Anselmino M, Solito B. Minimally invasive pharyngo-laryngo-esophagectomy: a salvage procedure for recurrent postcricoid esophageal cancer. Dis Esophagus. 2005;18:304–10.PubMedCrossRef
51.
Cense HA, Law S, Wei W, Lam LK, Ng WM, Wong KH, et al. Pharyngo laryngo esophagectomy using the thoracoscopic approach. Surg Endosc. 2007;21:879–84.PubMedCrossRef
52.
Sekido M, Yamamoto Y, Minakawa H, Sasaki S, Furukawa H, Sugihara T, et al. Use of the “supercharge” technique in esophageal and pharyngeal reconstruction to augment microvascular blood flow. Surgery. 2003;134:420–4.PubMedCrossRef
53.
Uchiyama H, Shirabe K, Morita M, Kakeji Y, Taketomi A, Soejima Y, et al. Expanding the applications of microvascular surgical techniques to digestive surgeries: a technical review. Surg Today. 2012;42:111–20.PubMedCrossRef
54.
Matsubara T, Ueda M, Nakajima T, Kamata S, Kawabata K. Elongated stomach roll with vascular microanastomosis for reconstruction of the esophagus after pharyngo laryngo esophagectomy. J Am Coll Surg. 1995;180:613–5.PubMed
55.
Sagawa N, Okushiba S, Ono K, Ito K, Morikawa T, Kondo S, et al. Reconstruction after total pharyngo laryngo esophagectomy. Comparison of elongated stomach roll with microvascular anastomosis with gastric pull up reconstruction or something like that. Langenbecks Arch Surg. 2000;385:34–8.PubMedCrossRef
56.
Kawahara H, Shiraishi T, Yasugawa H, Okamura K, Shirakusa T. A new surgical technique for voice restoration after laryngo pharyngo esophagectomy with a free ileocolic graft: preliminary report. Surgery. 1992;111:569–75.PubMed
57.
Motoyama S, Saito R, Maruyama K, Okuyama M, Sasaki K, Wako M, et al. Sound spectrogram analysis in patients receiving Kawahara’s surgical voice restoration for advanced carcinoma of the hypopharynx and cervical esophagus. Dis Esophagus. 2007;20:42–6.PubMedCrossRef
58.
Rampazzo A, Salgado CJ, Gharb BB, Mardini S, Spanio di Spilimbergo S, Chen HC. Donor-site morbidity after free ileocolon flap transfer for esophageal and voice reconstruction. Plast Reconstr Surg. 2008;122:186e–94e.PubMedCrossRef
59.
Chen HC, Gharb BB, Rampazzo A, Perrone F, Chen SH, Trignano E. Simultaneous restoration of voice function and digestive tract continuity in patients with synchronous primaries of hypopharynx and thoracic esophagus with pedicled ileocolon flap. Surgery. 2011;149:662–71.PubMedCrossRef
60.
Suga H, Okazaki M, Sarukawa S, Takushima A, Asato H. Free jejunal transfer for patients with a history of esophagectomy and gastric pull-up. Ann Plast Surg. 2007;58:182–5.PubMedCrossRef
61.
Hosoya Y, Sarukawa S, Matsumoto S, Zuiki T, Hyodo M, Abe K, et al. Esophagectomy and gastric pull-up in patients with previous free jejunal transfer. Ann Thorac Surg. 2009;87:647–9.PubMedCrossRef
62.
Martins AS, Lage HT, Lopes LR, Brandalise NA. Use of omentum pedicled graft to protect great vessels in gastric transposition for pharyngoesophageal cancer. J Surg Oncol. 1999;70:181–4.PubMedCrossRef
Metadaten
Titel
Surgical strategies for esophageal cancer associated with head and neck cancer
verfasst von
Masaru Morita
Hiroshi Saeki
Shuhei Ito
Yasue Kimura
Nami Yamashita
Koji Ando
Yukiharu Hiyoshi
Eriko Tokunaga
Eiji Oki
Tetsuo Ikeda
Sei Yoshida
Torahiko Nakashima
Yoshihiko Maehara
Publikationsdatum
01.09.2014
Verlag
Springer Japan
Erschienen in
Surgery Today / Ausgabe 9/2014
Print ISSN: 0941-1291
Elektronische ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-013-0713-3

Weitere Artikel der Ausgabe 9/2014

Surgery Today 9/2014 Zur Ausgabe

Case Report

Hemorrhage from the pancreatic cut end into the jejunum after binding pancreaticojejunostomy: report of a case

Original Article

Recent trends in hepatectomy for elderly patients with hepatocellular carcinoma

Case Report

Long-term survival after excision of a giant esophageal gastrointestinal stromal tumor with imatinib mesylate resistance: report of a case

Case Report

Surgical management of a primary external iliac venous aneurysm causing pulmonary thromboembolism: report of a case

How to Do It

Oncoplastic breast surgery combining partial mastectomy with immediate breast reshaping using a keyhole-shaped skin glandular flap for Paget’s disease

Original Article

Early postoperative results for females undergoing isolated coronary artery bypass surgery: comparison of the pre- and postmenopausal periods

Leitlinien kompakt für die Allgemeinmedizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Kostenlos registrieren

Facharzt-Training Allgemeinmedizin

Die ideale Vorbereitung zur anstehenden Prüfung mit den ersten 24 von 100 klinischen Fallbeispielen verschiedener Themenfelder

Mehr erfahren

Neu im Fachgebiet Allgemeinmedizin

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Metformin rückt in den Hintergrund

24.04.2024 DGIM 2024 Kongressbericht

Es hat sich über Jahrzehnte klinisch bewährt. Doch wo harte Endpunkte zählen, ist Metformin als alleinige Erstlinientherapie nicht mehr zeitgemäß.

Myokarditis nach Infekt – Richtig schwierig wird es bei Profisportlern

24.04.2024 DGIM 2024 Kongressbericht

Unerkannte Herzmuskelentzündungen infolge einer Virusinfektion führen immer wieder dazu, dass junge, gesunde Menschen plötzlich beim Sport einen Herzstillstand bekommen. Gerade milde Herzbeteiligungen sind oft schwer zu diagnostizieren – speziell bei Leistungssportlern. 

Update Allgemeinmedizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen
Bildnachweise