Erschienen in:
01.10.2019 | Pediatric oncologic imaging
Surveillance imaging in pediatric lymphoma
verfasst von:
Stephan D. Voss, Mitchell S. Cairo
Erschienen in:
Pediatric Radiology
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Ausgabe 11/2019
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Abstract
Current therapies used in treating children with Hodgkin lymphoma and many histological subtypes of non-Hodgkin lymphoma have resulted in overall survival rates exceeding 90% in many instances. With increasing concerns related to the cost of radiologic imaging, exposure to ionizing radiation, and potential false-positive results, the role of routine off-therapy surveillance imaging has been called into question. Although radiologic imaging plays an important role in diagnosing and assessing treatment response, in these children — the majority of whom have an excellent outcome following completion of therapy — there is an opportunity to dramatically reduce the number of off-therapy imaging evaluations. This review summarizes several recent studies in both Hodgkin and non-Hodgkin lymphoma providing evidence to support these efforts. In addition, we propose a surveillance imaging strategy that uses a novel risk-adapted and response-based approach to determine which children would most benefit from off-therapy imaging surveillance.