Erschienen in:
28.04.2017 | Editorial
Syndrome of inappropriate antidiuresis should it be managed by specialised endocrinologists?
verfasst von:
Aoife Garrahy, Chris J. Thompson
Erschienen in:
Endocrine
|
Ausgabe 2/2017
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Excerpt
The syndrome of inappropriate antidiuresis (SIAD) is the commonest cause of hyponatraemia in hospitalised patients, accounting for 43% of patients with a plasma sodium concentration of <130 mmol/l [
1]. Although there are virtually no data on mortality in SIAD, mortality in all-cause hyponatraemia has been reported to be elevated in almost every paper on the subject [
2‐
4]. Hyponatraemic patients are also vulnerable to morbidity related to falls [
5], fractures [
6] and osteoporosis [
7]. In the absence of separate studies in SIAD, it is widely accepted that patients who have hyponatraemia due to SIAD are vulnerable to the same risk of the morbidities and mortality associated with all-cause hyponatraemia. This has prompted considerable interest in whether treatment of hyponatreamia can improve outcomes in SIAD. …
