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01.10.2014 | Original Paper

Tailored Nutrition Education and Food Assistance Improve Adherence to HIV Antiretroviral Therapy: Evidence from Honduras

verfasst von: Homero Martinez, Kartika Palar, Sebastian Linnemayr, Alexandria Smith, Kathryn Pitkin Derose, Blanca Ramírez, Hugo Farías, Glenn Wagner

Erschienen in: AIDS and Behavior | Sonderheft 5/2014

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Abstract

Food insecurity and malnutrition negatively affect adherence to antiretroviral therapy (ART) and are associated with poor HIV clinical outcomes. We examined the effect of providing household food assistance and nutrition education on ART adherence. A 12-month prospective clinical trial compared the effect of a monthly household food basket (FB) plus nutrition education (NE) versus NE alone on ART adherence on 400 HIV patients at four clinics in Honduras. Participants had been receiving ART for an average of 3.7 years and were selected because they had suboptimal adherence. Primary outcome measures were missed clinic appointments, delayed prescription refills, and self-reported missed doses of ART. These three adherence measures improved for both groups over 12 months (p < 0.01), mostly within 6 months. On-time prescription refills improved for the FB plus NE group by 19.6 % more than the group receiving NE alone after 6 months (p < 0.01), with no further change at 12 months. Change in missed appointments and self-reported missed ART doses did not significantly differ by intervention group.

Deribe K, Hailekiros F, Biadgilign S, Amberbir A, Beyene B. Defaulters from antiretroviral treatment in Jimma University Specialized Hospital, Southwest Ethiopia. Trop Med Int Health. 2008;13(3):328–33.PubMedCrossRef

Franke M, Murray M, Muñoz M, et al. Food insufficiency is a risk factor for suboptimal antiretroviral therapy adherence among HIV-infected adults in urban Peru. AIDS Behav. 2011;15(7):1483–9.PubMedCrossRefPubMedCentral

Marcellin F, Boyer S, Protopopescu C, et al. Determinants of unplanned antiretroviral treatment interruptions among people living with HIV in Yaoundé, Cameroon (EVAL survey, ANRS 12-116). Trop Med Int Health. 2008;13(12):1470–8.PubMedCrossRef

Martin A, Palar K, Derose K, Adams J. Food insecurity and nutritional barriers to antiretroviral therapy: lessons from Latin America and the Caribbean. J HIV AIDS Soc Serv. 2011;10(2):194–214.CrossRef

Weiser S, Tuller D, Frongillo E, et al. Food Insecurity as a barrier to sustained antiretroviral therapy adherence in Uganda. PLoS One. 2010;5(4):357–66.CrossRef

Raiten D, Grinspoon S, Arpadi S. Nutritional considerations in the use of ART in resource-limited settings. Durban, South Africa; 2005. Report No.

Tuller DM, Bangsberg DR, Senkungu J, et al. Transportation costs impede sustained adherence and access to HAART in a clinic population in southwestern Uganda: a qualitative study. AIDS Behav. 2010;14(4):778–84.PubMedCrossRefPubMedCentral

Weiser S, Tsai AC, Gupta R, et al. Food insecurity is associated with morbidity and patterns of healthcare utilization among HIV-infected individuals in rural Uganda. AIDS. 2012;26(1):67–75.PubMedCrossRefPubMedCentral

Bärnighausen T, Chaiyachati K, Chimbindi N, et al. Interventions to increase antiretroviral adherence in sub-Saharan Africa: a systematic review of evaluation studies. Lancet Infect Dis. 2011;. doi:10.1016/S1473-3099(11)70181-5.PubMed

10.

Thompson MA, Mugavero MJ, Amico KR, et al. Guidelines for improving entry into and retention in care and antiretroviral adherence for persons with HIV: evidence-based recommendations from an international association of physicians in AIDS care panel. Ann Int Med. 2012;. doi:10.7326/0003-4819-156-11-201206050-00419.

11.

Cantrell R, Sinkala M, Megazinni K, et al. A pilot study of food supplementation to improve adherence to antiretroviral therapy among food-insecure adults in Lusaka, Zambia. J Acquir Immune Defic Syndr. 2008;49(2):190–5.PubMedCrossRef

12.

Serrano C, Laporte R, Ide M, et al. Family nutritional support improves survival, immune restoration and adherence in HIV patients receiving ART in developing country. Asia Pac J Clin Nutr. 2010;19(1):68–75.PubMed

13.

WHO. Nutrition Counseling, Care and Support for HIV-Infected Women. Guidelines on HIV-related care, treatment and support for HIV-infected women and their children in resource-constrained settings. Geneva: WHO, 2004.

14.

World Health Organization. Essential prevention and care interventions for adults and adolescents living with HIV in resource-limited settings. Geneva: World Health Organization; 2008.

15.

FANTA. HIV/AIDS: a guide for nutritional care and support. Washington, DC: Academy for Educational Development; 2004.

16.

World Bank. HIV/AIDS, nutrition and food security: what we can do—a synthesis of international guidance. Washington, DC: World Bank; 2007.

17.

Kaye HL, Moreno-Leguizamon CJ. Nutrition education and counselling as strategic interventions to improve health outcomes in adult outpatients with HIV: a literature review. Afr J AIDS Res. 2011;9(3):271–83.CrossRef

18.

Byron E, Gillespie S, Nangami M. Integrating nutrition security with treatment of people living with HIV: lessons from Kenya. Food Nutr Bull. 2008;29(2):87–97.PubMed

19.

Ivers L, Chang Y, Jerome J, Freedberg K. Food assistance is associated with improved body mass index, food security and attendance at clinic in an HIV program in central Haiti: a prospective observational cohort study. AIDS Res Ther. 2010;7(33):1–8.

20.

Martin A, Palar K. HIV/AIDS policy, food and nutrition in Latin America and the Caribbean. Panama City: The World Food Programme; 2011.

21.

WHO, UNAIDS, UNICEF. HIV and infant feeding counselling: a training course. Director’s guide. Geneva, Switzerland: World Health Organization; 2000.

22.

Nutritional care and support for people living with HIV/AIDS in Uganda: guidelines for service providers. Uganda: STD/AIDS Control Programme, Ministry of Health.

23.

World Health Organization. Nutrition counselling, care and support for HIV-infected women: guidelines on HIV-related care, treatment and support for HIV-infected women and their children in resource-limited settings. Geneva: World Health Organization, Department of HIV/AIDS and Department of Nutrition for Health and Development; 2004.

24.

Fisher J, Fisher W. Changing AIDS-risk behavior. Psychol Bull. 1992;111(3):455–74.PubMedCrossRef

25.

Fisher JD, Fisher WA, Shuper PA. The information motivation-behavioral skills model of HIV preventive behavior. In: Diclemente R, Crosby R, Kegler M, editors. Emerging theories in health promotion practice and research. 2nd ed. San Francisco: Jossey Bass; 2009. p. 21–64.

26.

Palar, K. Food Security, Livelihoods, and Antiretroviral Therapy for HIV. Evidence for policy in resource-limited settings. Santa Monica, CA: Pardee RAND Graduate School; 2012.

27.

Tirivayi N, Groot W. Health and welfare effects of integrating AIDS treatment with food assistance in resource constrained settings: a systematic review of theory and evidence. Soc Sci Med. 2011;73(5):685–92.PubMedCrossRef

28.

Anema A, Vogenthaler N, Frongillo E, Kadiyala S, Weiser S. Food insecurity and HIV/AIDS: current knowledge, gaps, and research priorities. Curr HIV/AIDS Rep. 2009;6(4):224–31.PubMedCrossRef

29.

Weiser S, Young S, Cohen C, et al. Conceptual framework for understanding the bidirectional links between food insecurity and HIV/AIDS. Am J Clin Nutr. 2011;. doi:10.3945/ajcn.111.012070.PubMedPubMedCentral

30.

Tsai AC, Bangsberg DR, Emenyonu N, et al. The social context of food insecurity among persons living with HIV/AIDS in rural Uganda. Soc Sci Med. 2011;73(12):1717–24.PubMedCrossRefPubMedCentral

31.

Habicht J. Estandarización de metodos epidemiológicos cuantitativos sobre el terreno; Standardization of quantitative epidemiological methods in the field. Bol Of Sanit Panamer. 1974;76(5):375–84.

32.

World Health Organization. BMI classification, Geneva. http://apps.who.int/bmi/index.jsp?introPage=intro_3.html. Accessed 17 Apr 2012.

33.

Kroenke K, Spitzer RL, Williams JBW. The PHQ-9: validity of a brief depression severity measure. J Gen Int Med. 2001;16(9):606–13.CrossRef

34.

Melgar-Quiñonez H, Alvarez Uribe M, Fonseca Centeno Z, et al. Características Psicométricas de la Escala de Seguridad Alimentaria ELCSA aplicada en Colombia, Guatemala y México. Segur Alimentar Nutric. 2010;17(1):48–60.

35.

Thirumurthy H, Pop-Eleches C, Habyarimana J, Goldstein M, Graff Zivin J. Behavioral responses of patients in AIDS treatment programs: sexual behavior in Kenya. Forum Health Econ Policy. 2012;15(2):1–29.CrossRef

36.

Zeger SL, Liang KY, Albert PS. Models for longitudinal data: a generalized estimating equation approach. Biometrics. 1988;44:1049–60.PubMedCrossRef

37.

Sterne JAC, White IR, Carlin JB, et al. Multiple imputation for missing data in epidemiological and clinical research: potential and pitfalls. BMJ. 2009;338:3293.CrossRef

38.

Tirivayi N, Koethe J, Groot W. Clinic-based food assistance is associated with increased medication adherence among HIV-infected adults on long-term antiretroviral therapy in Zambia. J AIDS Clinic Res. 2012;3(7):171.CrossRef

39.

Posse M, Tirivayi N, Saha U, Baltussen R. The effect of food assistance on adherence to antriretroviral therapy among HIV/AIDS patients in Sofala Province, in Mozambique: a retrospective study. J AIDS Clin Res. 2013;4:198.CrossRef

40.

Anema A, Vogenthaler N, Frongillo E, Kadiyala S, Weiser S. Food insecurity and HIV/AIDS: current knowledge, gaps, and research priorities. Cur HIV/AIDS Rep. 2009;6(4):224–31.CrossRef

41.

Gibbons R, Hedeker D, DuToit S. Advances in analysis of longitudinal data. Ann Rev Clin Psychol. 2010;6:79.CrossRef

42.

Bell R, McCaffrey D. Bias reduction in standard errors for linear regression with multi-stage samples. Surv Methods. 2002;28(2):169–82.

43.

Gibbons RD, Hedeker D, DuToit S. Advances in analysis of longitudinal data. Annu Rev Clin Psychol. 2010;6:79.PubMedCrossRefPubMedCentral

44.

Franke RH, Kaul JD. The Hawthorne experiments: first statistical interpretation. Am Sociol Rev. 1978;43:623–43.CrossRef

45.

Sztam KA, Fawzi WW, Duggan C. Macronutrient supplementation and food prices in HIV treatment. J Nutr. 2010;140(1):213S–23S.PubMedCrossRefPubMedCentral

Titel: Tailored Nutrition Education and Food Assistance Improve Adherence to HIV Antiretroviral Therapy: Evidence from Honduras
verfasst von: Homero Martinez
Kartika Palar
Sebastian Linnemayr
Alexandria Smith
Kathryn Pitkin Derose
Blanca Ramírez
Hugo Farías
Glenn Wagner
Publikationsdatum: 01.10.2014
Verlag: Springer US
Erschienen in: AIDS and Behavior / Ausgabe Sonderheft 5/2014
Print ISSN: 1090-7165
Elektronische ISSN: 1573-3254
DOI: https://doi.org/10.1007/s10461-014-0786-z

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