Erschienen in:
02.05.2018 | Original Article
Tea, coffee, and head and neck cancer risk in a multicenter study in east Asia
verfasst von:
Shuang Li, Yuan-Chin Amy Lee, Qian Li, Chien-Jen Chen, Wan-Lun Hsu, Pen-Jen Lou, Cairong Zhu, Jian Pan, Hongbing Shen, Hongxia Ma, Lin Cai, Baochang He, Yu Wang, Xiaoyan Zhou, Qinghai Ji, Baosen Zhou, Wei Wu, Jie Ma, Paolo Boffetta, Zuo-Feng Zhang, Min Dai, Mia Hashibe
Erschienen in:
Oral Cancer
|
Ausgabe 1-2/2018
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Abstract
Purpose
The role of tea or coffee on head and neck cancer (HNC) risk has not been consistent, especially in Asian populations. The aim of the study was to investigate whether tea or coffee is associated with HNC risks in a Chinese population.
Methods
Our case–control study included 921 head and neck cancer cases and 806 controls. We obtained information on tea and coffee consumption frequency, duration, age at start, strength, and types. Unconditional logistic regression was used to estimate the odds ratios (ORs) and 95% confidence intervals (95% CIs).
Results
No association between tea drinking and HNC risk was observed after adjusting for potential confounders. Coffee drinking was inversely associated with oral cavity cancer risk with dose–response trends for both frequency (p for trend = 0.0149) and the duration (p for trend = 0.0167) of intake. When stratified by age, sex, and cigarette smoking, coffee drinking was not clearly associated with head and neck cancer risk in terms of frequency or duration.
Conclusion
Coffee consumption was associated with a decreased risk of oral cavity cancer. Further investigations with more specific tea consumption-related factors are warranted to examine the relationship between tea drinking and HNC risks.