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03.07.2020 | Review Article

Thalassemia in the emergency department: special considerations for a rare disease

verfasst von: Antoine N. Saliba, Ali Atoui, Mohamad Labban, Hani Hamade, Rayan Bou-Fakhredin, Afif Mufarrij, Ali T. Taher

Erschienen in: Annals of Hematology | Ausgabe 9/2020

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Abstract

Thalassemia is characterized by a defect in the synthesis of one or more of the globin subunits of hemoglobin. This defect results in imbalance in the α/β-globin chain ratio, ineffective erythropoiesis, chronic hemolytic anemia, and iron overload. With advances in diagnosis, treatment, and transfusion support, the prognosis of patients with thalassemia has improved over the past few decades. An increasing number of patients with thalassemia is living with long-term complications, including cardiomyopathy, chronic liver disease, endocrinopathy, and infections. In this paper, we review common complications that bring the patient with thalassemia to urgent or emergent medical attention. We also discuss the aspects of emergency care that are most relevant while caring for the patient with thalassemia in the emergency department.

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Titel: Thalassemia in the emergency department: special considerations for a rare disease
verfasst von: Antoine N. Saliba
Ali Atoui
Mohamad Labban
Hani Hamade
Rayan Bou-Fakhredin
Afif Mufarrij
Ali T. Taher
Publikationsdatum: 03.07.2020
Verlag: Springer Berlin Heidelberg
Erschienen in: Annals of Hematology / Ausgabe 9/2020
Print ISSN: 0939-5555
Elektronische ISSN: 1432-0584
DOI: https://doi.org/10.1007/s00277-020-04164-6

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