Erschienen in:
16.10.2018 | Short Communication
The 8th edition AJCC/UICC TNM staging for p16-positive oropharyngeal carcinoma: is there space for improvement?
verfasst von:
Shachi Jenny Sharma, Steffen Wagner, Henrike Simone Frauke Reder, Tobias Kroll, Nora Wuerdemann, Jens Peter Klussmann, Claus Wittekindt
Erschienen in:
European Archives of Oto-Rhino-Laryngology
|
Ausgabe 12/2018
Einloggen, um Zugang zu erhalten
Abstract
The 8th edition of the AJCC/UICC TNM-staging system for p16[HPV]-positive OPSCC manages to improve prediction of prognosis and will essentially influence choice of therapy in future. Nonetheless, adjustments of the current version are needed. The surrogate marker p16 alone is inadequate for HPV detection, the role of ECS in HPV-positive OPSCC is not fully understood, and the patient’s characteristics as well as molecular signatures and genetics have not been taken into consideration yet.