The online version of this article (doi:10.1186/1471-2318-14-144) contains supplementary material, which is available to authorized users.
The authors declare that they have no competing interests.
YPK, HSH and ILS conceptualized the study design. YPK conducted analyses. YPK, JYJ and SK wrote the first draft of the paper. All authors critically revised the manuscript and read and approved the final version.
This study was conducted to determine the prevalence of a low appendicular skeletal muscle index (ASMI) using three cut-off points (mean ASMI-2SD of a gender-specific young reference group (aged 18–39 years), mean ASMI-1SD of a gender-specific young reference group, and the lower 20 percentile value of a gender-specific older group (aged ≥ 65 years)) in Korean older people and the relationship between ASMI and subjective health-related quality of life.
This study utilized data acquired during the Korean National Health and Nutrition Examination Survey (KNHANES) from 2008–2011. Dual-energy X-ray absorptiometry body compositional data was obtained from a subsample of 6538 subjects (men 2804, women 3734) aged 18–39 and 4413 subjects (men 1872, women 2541) aged 65 years and older. The three definitions of low appendicular skeletal muscle and the EQ-5D-3 L-Korean descriptive system were applied to Korean older people.
For the ASMI cutoff points used, in men, the three cutoff points were ASMI 2SD (6.09 kg/m2), ASMI 20 (6.48 kg/m2), and ASMI 1SD (6.95 kg/m2). In women, ASMI 2SD (4.38 kg/m2) was the lowest, followed by ASMI 1SD (4.96 kg/m2) and ASMI 20 (5.33 kg/m2). Proportions of older subjects with a low ASMI using the three cutoff points were 9.7% (ASMI 2SD) and 40.9% (ASMI 1SD) in men, and 0.7% (ASMI 2SD) and 7.4% (ASMI 1SD) in women. By multivariate ordinal logistic regression analysis, men with a low ASMI had significantly high odd ratios for the three domains of mobility (p < 0.001), self-care (p = 0.005), and usual activities (p = 0.004) among the five domains of the EQ-5D and EQ-5D index (p = 0.010).
The ASMI 2SD cut-off points for older Koreans, 6.09 kg/m2 for men and 4.38 kg/m2 for women, resulted in low prevalences of a low ASM, that is, 9.7% for men and 0.7% for women, and showed low clinical usefulness due to very low determined prevalence in women. Hence, we suggest that the cut-off point of the lowest 20% of Korean older people (men: 6.48 kg/m2, women; 5.33 kg/m2) be used for older Koreans.
Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, Martin FC, Michel JP, Rolland Y, Schneider SM, Topinkova E, Vandewoude M, Zamboni M: Sarcopenia: European consensus on definition and diagnosis: report of the European working group on sarcopenia in older people. Age Ageing. 2010, 39 (4): 412-423. 10.1093/ageing/afq034. CrossRefPubMedPubMedCentral
Fielding RA, Vellas B, Evans WJ, Bhasin S, Morley JE, Newman AB, Abellan Van Kan G, Andrieu S, Bauer J, Breuille D, Cederholm T, Chandler J, Meynard CD, Donini L, Harris T, Kannt A, Guibert FK, Onder G, Papanicolaou D, Rolland Y, Rooks D, Sieber C, Souhami E, Verlaan S, Zamboni M: Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Assoc. 2011, 12 (4): 249-256. 10.1016/j.jamda.2011.01.003. CrossRef
Rosenberg IH: Summary comments. Am J Clin Nutr. 1989, 50 (5): 1231-1233.
Studenski SA, Peters KW, Alley DE, Cawthon PM, McLean RR, Harris TB, Ferrucci L, Guralnik JM, Fragala MS, Kenny AM: The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates. J Gerontol A: Biol Med Sci. 2014, 69 (5): 547-558. 10.1093/gerona/glu010. CrossRef
Chen L-K, Liu L-K, Woo J, Assantachai P, Auyeung T-W, Bahyah KS, Chou M-Y, Chen L-Y, Hsu P-S, Krairit O: Sarcopenia in Asia: consensus report of the Asian working group for sarcopenia. J Am Med Assoc. 2014, 15 (2): 95-101. 10.1016/j.jamda.2013.11.025. CrossRef
Batsis JA, Barre LK, Mackenzie TA, Pratt SI, Lopez-Jimenez F, Bartels SJ: Variation in the prevalence of sarcopenia and sarcopenic obesity in older adults associated with different research definitions: dual-energy X-Ray absorptiometry data from the national health and nutrition examination survey 1999–2004. J Am Geriatr Soc. 2013, 61 (6): 974-980. 10.1111/jgs.12260. CrossRefPubMed
Oh K, Lee J, Lee B, Kweon S, Lee Y, Kim Y: Plan and operation of the 4th Korea national health and nutrition examination survey (KNHANES IV). Korean J Epidemiol. 2007, 29 (2): 139-145.
McDonald JH: Handbook of biological statistics. Sparky House Publishing Baltimore. 2009: 141-144.
The EuroQol Group: EuroQol-a new facility for the measurement of health-related quality of life. Health Policy. 1990, 16 (3): 199-208. CrossRef
Nam H, Kim K, Kwon S, Koh K, Poul K: EQ-5D Korean valuation study using time trade of method. 2007, Seoul: Korea Centers for Disease Control and Prevention
WHO Expert Consultation: Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet. 2004, 363 (9403): 157-163. CrossRef
Lee B, Lee C, Lee P, Choi M, Namkoong K: Development of Korean version of alcohol use disorders identification test (AUDIT-K): Its reliability and validity. J Korean Academy of Addiction Psychiatry. 2000, 4: 83-92.
Lee W-J, Liu L-K, Peng L-N, Lin M-H, Chen L-K: Comparisons of sarcopenia defined by IWGS and EWGSOP criteria among older people: results from the I-Lan longitudinal aging study. J Am Med Dir Assoc. 2013, 14 (7): 528.e521-528.e527. CrossRef
Lim S, Kim JH, Yoon JW, Kang SM, Choi SH, Park YJ, Kim KW, Lim JY, Park KS, Jang HC: Sarcopenic obesity: prevalence and association with metabolic syndrome in the Korean Longitudinal Study on Health and Aging (KLoSHA). Diabetes Care. 2010, 33 (7): 1652-1654. 10.2337/dc10-0107. CrossRefPubMedPubMedCentral
Size Korea: Report on the Sixth Survey of Korean anthropometry. Korean ministry of trade, industry and energy. 2010
Park HS, Lee HO, Sung CJ: Body image, eating problems and dietary intakes among female college students in urban area of Korea. Korean J Community Nutrition. 1997, 2 (4): 505-514.
Cattarin JA, Thompson JK, Thomas C, Williams R: Body image, mood, and televised images of attractiveness: the role of social comparison. J Soc Clin Psychol. 2000, 19 (2): 220-239. 10.1521/jscp.2000.19.2.220. CrossRef
Wardle J, Haase A, Steptoe A: Body image and weight control in young adults: international comparisons in university students from 22 countries. Int J Obes. 2005, 30 (4): 644-651. CrossRef
Kim BR, Han YB, Chang UJ: A study on the attitude toward control, diet behavior and food habits of college students. Korean J Community Nutrition. 1997, 2 (4): 530-538.
Lee MS, Woo MK: Differences in the dietary and health-related habits and quality of diet in university students living in Daejeon. Korean J Community Nutrition. 2003, 8 (1): 33-40.
- The application of different appendicular skeletal muscle cutoff points and research definitions associated with health-related quality of life in Korean older people: data from KNHANES 2008–2011
- BioMed Central
Neu im Fachgebiet Innere Medizin
Meistgelesene Bücher aus der Inneren Medizin
Mail Icon II