Background
Methods
Study population
Demographic and laboratory measurements
Statistical analyses
Results
Patient characteristics
Variables | Body mass index, kg/m2 | ||||
---|---|---|---|---|---|
Total | < 20 | 20 to < 23 | ≥23 | P value | |
N (%) | 18,242 | 5681 (31) | 6973 (38) | 5588 (31) | |
Age, years | 59 ± 14 | 58 ± 16 | 59 ± 14 | 59 ± 13 | 0.383 |
Male, % | 59 | 52 | 63 | 61 | < 0.001 |
Vintage, year | 1.5 (0.5–4.1) | 1.9 (0.5–5.2) | 1.5 (0.5–4.2) | 1.2 (0.4–3.3) | < 0.001 |
ESRD reason, % | |||||
Diabetes | 43 | 37 | 43 | 49 | < 0.001 |
Hypertension | 19 | 18 | 19 | 20 | 0.031 |
Glomerulonephritis | 12 | 15 | 12 | 10 | < 0.001 |
Others | 26 | 30 | 26 | 21 | < 0.001 |
Comorbidities, % | |||||
Diabetes | 43 | 37 | 43 | 49 | < 0.001 |
Hypertension | 30 | 30 | 30 | 29 | 0.088 |
Cardiovascular disease | 8 | 8 | 8 | 8 | 0.359 |
Single pool Kt/V | 1.4 ± 0.3 | 1.5 ± 0.4 | 1.4 ± 0.3 | 1.4 ± 0.3 | < 0.001 |
Urea reduction ratio, % | 69 (64–74) | 72 (67–76) | 69 (64–74) | 67 (63–72) | < 0.001 |
Treatment time, min | 239 ± 11 | 238 ± 12 | 239 ± 10 | 239 ± 11 | < 0.001 |
Predialysis SBP, mmHg | 146 ± 20 | 145 ± 20 | 146 ± 20 | 145 ± 19 | 0.236 |
Predialysis DBP, mmHg | 81 ± 11 | 82 ± 11 | 81 ± 11 | 81 ± 11 | < 0.001 |
Presence of RKF, % | 6 | 5 | 6 | 7 | < 0.001 |
Hemoglobin, g/dL | 10.1 ± 1.3 | 9.9 ± 1.3 | 10.1 ± 1.2 | 10.2 ± 1.2 | < 0.001 |
nPCR, g/kg/day | 1.0 ± 0.8 | 0.9 ± 0.7 | 1.0 ± 0.8 | 1.0 ± 0.8 | < 0.001 |
Association of spKt/V and all-cause mortality according to body mass index strata
spKt/V | Model 1 | Model 2 | Model 3 | |||
---|---|---|---|---|---|---|
HRs | 95% CI | HRs | 95% CI | HRs | 95% CI | |
< 1.0 | 1.3 | 1.16–1.45 | 1.33 | 1.19–1.49 | 1.17 | 1.05–131 |
1.0 to < 1.2 | 1.05 | 0.96–1.15 | 1.09 | 1.00–1.19 | 1.03 | 0.94–1.13 |
1.2 to < 1.4 | Reference | Reference | Reference | |||
1.4 to < 1.6 | 0.92 | 0.85–1.00 | 0.93 | 0.86–1.01 | 0.95 | 0.87–1.02 |
1.6 to < 1.8 | 0.85 | 0.78–0.94 | 0.86 | 0.78–0.95 | 0.89 | 0.81–0.98 |
≥1.8 | 0.85 | 0.76–0.94 | 0.86 | 0.77–0.96 | 0.88 | 0.79–0.99 |