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Current Diabetes Reports
Erschienen in: Current Diabetes Reports 12/2019

01.12.2019 | Diabetes and Pregnancy (M-F Hivert and CE Powe, Section Editors)

The Effects of Lifestyle and/or Vitamin D Supplementation Interventions on Pregnancy Outcomes: What Have We Learned from the DALI Studies?

verfasst von: Jürgen Harreiter, Gernot Desoye, Mireille N. M. van Poppel, Alexandra Kautzky-Willer, Fidelma Dunne, Rosa Corcoy, Roland Devlieger, David Simmons, Juan M. Adelantado, Peter Damm, Elizabeth Reinhardt Mathiesen, Dorte Moeller Jensen, Lise Lotte T. Anderson, Annunziata Lapolla, Maria G. Dalfrà, Alessandra Bertolotto, Ewa Wender-Ozegowska, Agnieszka Zawiejska, David J. Hill, Frank J. Snoek, on behalf of the DALI Consortium

Erschienen in: Current Diabetes Reports | Ausgabe 12/2019

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Abstract

Purpose of Review

The DALI (vitamin D and lifestyle intervention in the prevention of gestational diabetes mellitus (GDM)) study aimed to prevent GDM with lifestyle interventions or Vitamin D supplementation (1600 IU/day). This review summarizes the learnings from the DALI studies among pregnant women with a BMI ≥ 29 kg/m2.

Recent Findings

Women diagnosed with GDM earlier in pregnancy had a worse metabolic profile than those diagnosed later. A combined physical activity (PA) and healthy eating (HE) lifestyle intervention improved both behaviours, limited gestational weight gain (GWG) and was cost-effective. Although GDM risk was unchanged, neonatal adiposity was reduced due to less sedentary time. Neither PA nor HE alone limited GWG or GDM risk. Fasting glucose was higher with HE only intervention, and lower with Vitamin D supplementation.

Summary

Our combined intervention did not prevent GDM, but was cost-effective, limited GWG and reduced neonatal adiposity.
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Metadaten
Titel
The Effects of Lifestyle and/or Vitamin D Supplementation Interventions on Pregnancy Outcomes: What Have We Learned from the DALI Studies?
verfasst von
Jürgen Harreiter
Gernot Desoye
Mireille N. M. van Poppel
Alexandra Kautzky-Willer
Fidelma Dunne
Rosa Corcoy
Roland Devlieger
David Simmons
Juan M. Adelantado
Peter Damm
Elizabeth Reinhardt Mathiesen
Dorte Moeller Jensen
Lise Lotte T. Anderson
Annunziata Lapolla
Maria G. Dalfrà
Alessandra Bertolotto
Ewa Wender-Ozegowska
Agnieszka Zawiejska
David J. Hill
Frank J. Snoek
on behalf of the DALI Consortium
Publikationsdatum
01.12.2019
Verlag
Springer US
Erschienen in
Current Diabetes Reports / Ausgabe 12/2019
Print ISSN: 1534-4827
Elektronische ISSN: 1539-0829
DOI
https://doi.org/10.1007/s11892-019-1282-7

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