Erschienen in:
01.12.2015 | Topic Review & Clinical Guidelines
The role of biopsy in the management of patients with presumed diffuse low grade glioma
A systematic review and evidence-based clinical practice guideline
verfasst von:
Brian T. Ragel, Timothy C. Ryken, Steven N. Kalkanis, Mateo Ziu, Daniel Cahill, Jeffrey J. Olson
Erschienen in:
Journal of Neuro-Oncology
|
Ausgabe 3/2015
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Abstract
Question
What is the optimal role of biopsy in the initial management of presumptive low-grade glioma in adults?
Target population
Adult patients with imaging suggestive of a low-grade glioma.
Recommendations
Level III
Stereotactic biopsy is recommended when definitive surgical resection is limited by lesions that are deep-seated, not resectable, and/or located within eloquent cortex, or in patients unable to undergo craniotomy due to medical co-morbidities to obtain the critical tissue diagnosis needed for targeted treatment planning for patients with low-grade gliomas.
Question
What is the best technique for brain biopsy?
Target population
Adult patients with imaging suggestive of a low-grade glioma.
Recommendations
Level III
Frameless and frame-based stereotactic brain biopsy for low-grade gliomas are recommended based on clinical circumstances as they provide similar diagnostic yield, diagnostic accuracy, morbidity, and mortality. It is recommended the surgeon consider advanced imaging techniques (e.g., perfusion, spectroscopy, metabolic studies) to target specific regions of interest to potentially improve diagnostic accuracy.