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Clinical Autonomic Research
Erschienen in: Clinical Autonomic Research 3/2014

01.06.2014 | Research Article

The role of cardiac pacing in carotid sinus syndrome: a meta-analysis

verfasst von: Bing-Wei Chen, Zhi-Guang Wang, Na-Qiang Lv, Yan-Mei Cheng, Ai-Min Dang

Erschienen in: Clinical Autonomic Research | Ausgabe 3/2014

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Abstract

Purpose

Cardiac pacing can be used to treat carotid sinus syndrome (CSS), but clinical studies have shown conflicting results. We conducted a systematic review and meta-analysis to evaluate the role of pacing for CSS.

Methods

A systematic search of publications in PubMed, Embase, and the Cochrane Library without language restriction was performed. Prospective randomized studies that compared cardiac pacing with standard therapy or pacing with different algorithms were included if the recurrence of syncope or the number of falls was observed.

Results

Eight studies enrolling 540 patients were identified. In open-label studies, the recurrence of syncope was reduced significantly by cardiac pacing compared with standard therapy. The recurrence of syncope was not different between single- and dual-chamber pacing, but a lower rate of patients with pre-syncope was observed in the group with dual-chamber pacing. Double-blind clinical studies failed to observe the role of cardiac pacing for preventing falls in patients with CSS.

Conclusion

The results of meta-analysis supported the use of cardiac pacing for patients with dominant cardioinhibitory CSS.
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Metadaten
Titel
The role of cardiac pacing in carotid sinus syndrome: a meta-analysis
verfasst von
Bing-Wei Chen
Zhi-Guang Wang
Na-Qiang Lv
Yan-Mei Cheng
Ai-Min Dang
Publikationsdatum
01.06.2014
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Autonomic Research / Ausgabe 3/2014
Print ISSN: 0959-9851
Elektronische ISSN: 1619-1560
DOI
https://doi.org/10.1007/s10286-014-0238-x

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