Skip to main content
Erschienen in: Current Diabetes Reports 5/2010

01.10.2010

The Value of National Diabetes Registries: SEARCH for Diabetes in Youth Study

verfasst von: Dana Dabelea, Elizabeth J. Mayer-Davis, Giuseppina Imperatore

Erschienen in: Current Diabetes Reports | Ausgabe 5/2010

Einloggen, um Zugang zu erhalten

Abstract

Diabetes mellitus is one of the most common severe chronic diseases of childhood. Much of our knowledge of the epidemiology of diabetes in young people has been generated by large collaborative efforts based on standardized registry data, such as the DIAMOND Project worldwide and the EURODIAB study in Europe. These registries showed that although at the start of the 20th century childhood diabetes was rare, by the end of the century a steady increase in incidence had been reported in many parts of the world. However, epidemiologic data for temporal trends in pediatric diabetes are still lacking or are minimal for most of the global population of youth, including in the United States. In addition, the epidemiology of diabetes in youth is changing. As youth are becoming increasingly overweight, we are seeing more obese children with a clinical phenotype of type 2 diabetes or “adult-onset” diabetes. It is imperative that efforts directed at surveillance of diabetes in young people continue and expand, not only to understand its complex etiology, but also because of its increasing public health importance.
Literatur
1.
Zurück zum Zitat DIAMOND Project Group: Incidence and trends of childhood type 1 diabetes worldwide 1990–1999. Diabet Med 2006, 23:857–866.CrossRef DIAMOND Project Group: Incidence and trends of childhood type 1 diabetes worldwide 1990–1999. Diabet Med 2006, 23:857–866.CrossRef
2.
Zurück zum Zitat Green A, Gale EA, Patterson CC: Incidence of childhood-onset insulin-dependent diabetes mellitus: the EURODIAB ACE study. Lancet 1992, 339:1113–1119. Green A, Gale EA, Patterson CC: Incidence of childhood-onset insulin-dependent diabetes mellitus: the EURODIAB ACE study. Lancet 1992, 339:1113–1119.
3.
Zurück zum Zitat Green A, Patterson CC: Trends in the incidence of childhood-onset diabetes in Europe 1989–1998. Diabetologia 2001, 44:B3–B8.CrossRefPubMed Green A, Patterson CC: Trends in the incidence of childhood-onset diabetes in Europe 1989–1998. Diabetologia 2001, 44:B3–B8.CrossRefPubMed
4.
Zurück zum Zitat LaPorte RE, Tajima N, Akerblom HK, et al.: Geographic differences in the risk of insulin-dependent diabetes mellitus: the importance of registries. Diabetes Care 1985, 8(Suppl 1):101–107.PubMed LaPorte RE, Tajima N, Akerblom HK, et al.: Geographic differences in the risk of insulin-dependent diabetes mellitus: the importance of registries. Diabetes Care 1985, 8(Suppl 1):101–107.PubMed
5.
Zurück zum Zitat Green A, King HO, LaPorte RE: Workshop on diabetes registries, the role of IDDM registries in diabetes research and care: summary report. In Diabetes. Edited by Serrano-Rios M, Lefebvre PJ. Amsterdam: Elsevier Science Publishers B.V.; 1985:443–448. Green A, King HO, LaPorte RE: Workshop on diabetes registries, the role of IDDM registries in diabetes research and care: summary report. In Diabetes. Edited by Serrano-Rios M, Lefebvre PJ. Amsterdam: Elsevier Science Publishers B.V.; 1985:443–448.
6.
Zurück zum Zitat •• Patterson CC, Dahlquist GG, Gyurus E, et al.: Incidence trends for childhood type 1 diabetes in Europe during 1989–2003 and predicted new cases 2005-20: a multicentre prospective registration study. Lancet 2009, 373:2027–2033. This paper provides updated estimates of trends in incidence of T1D in individuals less than 15 years of age in Europe, from 1989 to 2003. Fifteen-year incidence data collected by 20 population-based registries in 17 countries were used to estimate rates of increase in geographic regions within Europe. Model-based rates of increase were then used to predict the number of new cases throughout Europe by 2020. The prediction is that new cases in European children less than 5 years of age will double, and the prevalence of cases in those under 15 years of age will increase by 70%, between 2005 and 2020.CrossRefPubMed •• Patterson CC, Dahlquist GG, Gyurus E, et al.: Incidence trends for childhood type 1 diabetes in Europe during 1989–2003 and predicted new cases 2005-20: a multicentre prospective registration study. Lancet 2009, 373:2027–2033. This paper provides updated estimates of trends in incidence of T1D in individuals less than 15 years of age in Europe, from 1989 to 2003. Fifteen-year incidence data collected by 20 population-based registries in 17 countries were used to estimate rates of increase in geographic regions within Europe. Model-based rates of increase were then used to predict the number of new cases throughout Europe by 2020. The prediction is that new cases in European children less than 5 years of age will double, and the prevalence of cases in those under 15 years of age will increase by 70%, between 2005 and 2020.CrossRefPubMed
7.
Zurück zum Zitat •• Vehik K, Hamman RF, Lezotte D, et al.: Increasing incidence of type 1 diabetes in 0- to 17-year-old Colorado youth. Diabetes Care 2007, 30:503–509. Using data from the Colorado IDDM registry and the SEARCH-Colorado site, the incidence of T1D was shown to have increased in youth ≤17 years of age over the past three decades. During a 26-year period, the incidence of T1D increased by 2.3% (95% CI, 1.6–3.1) per year. The increase was significant for both NHW (2.7%; 95% CI, 1.9 –3.6 per year; P < 0.0001) and Hispanic youth (1.6%; 0.2–3.1 per year; P < 0.013). The increase in incidence was highest among the 0- to 4-year-old age group (3.5%; 95% CI, 2.1–4.9 per year; P < 0.001).CrossRefPubMed •• Vehik K, Hamman RF, Lezotte D, et al.: Increasing incidence of type 1 diabetes in 0- to 17-year-old Colorado youth. Diabetes Care 2007, 30:503–509. Using data from the Colorado IDDM registry and the SEARCH-Colorado site, the incidence of T1D was shown to have increased in youth ≤17 years of age over the past three decades. During a 26-year period, the incidence of T1D increased by 2.3% (95% CI, 1.6–3.1) per year. The increase was significant for both NHW (2.7%; 95% CI, 1.9 –3.6 per year; P < 0.0001) and Hispanic youth (1.6%; 0.2–3.1 per year; P < 0.013). The increase in incidence was highest among the 0- to 4-year-old age group (3.5%; 95% CI, 2.1–4.9 per year; P < 0.001).CrossRefPubMed
8.
Zurück zum Zitat Secular trends in incidence of childhood IDDM in 10 countries. Diabetes Epidemiology Research International (DERI) Group [no authors listed]. Diabetes 1990, 39:858–864. Secular trends in incidence of childhood IDDM in 10 countries. Diabetes Epidemiology Research International (DERI) Group [no authors listed]. Diabetes 1990, 39:858–864.
9.
Zurück zum Zitat Glaser SL, Clarke CA, Gomez SL, et al.: Cancer surveillance research: a vital subdiscipline of cancer epidemiology. Cancer Causes Control 2005, 16:1009–1019.CrossRefPubMed Glaser SL, Clarke CA, Gomez SL, et al.: Cancer surveillance research: a vital subdiscipline of cancer epidemiology. Cancer Causes Control 2005, 16:1009–1019.CrossRefPubMed
10.
Zurück zum Zitat Wingo PA, Howe HL, Thun MJ, et al.: A national framework for cancer surveillance in the United States. Cancer Causes Control 2005, 16:151–170.CrossRefPubMed Wingo PA, Howe HL, Thun MJ, et al.: A national framework for cancer surveillance in the United States. Cancer Causes Control 2005, 16:151–170.CrossRefPubMed
11.
Zurück zum Zitat Liese AD, Lawson A, Song HR, et al.: Evaluating geographic variation in type 1 and type 2 diabetes mellitus incidence in youth in four US regions. Health Place 2010, 16:547–556.CrossRefPubMed Liese AD, Lawson A, Song HR, et al.: Evaluating geographic variation in type 1 and type 2 diabetes mellitus incidence in youth in four US regions. Health Place 2010, 16:547–556.CrossRefPubMed
12.
Zurück zum Zitat Wadwa RP, Urbina EM, Anderson AM, et al.: Measures of arterial stiffness in youth with type 1 and type 2 diabetes: the SEARCH for diabetes in youth study. Diabetes Care 2010, 33:881–886.CrossRefPubMed Wadwa RP, Urbina EM, Anderson AM, et al.: Measures of arterial stiffness in youth with type 1 and type 2 diabetes: the SEARCH for diabetes in youth study. Diabetes Care 2010, 33:881–886.CrossRefPubMed
13.
Zurück zum Zitat Dabelea D, Mayer-Davis EJ, Lamichhane AP, et al.: Association of intrauterine exposure to maternal diabetes and obesity with type 2 diabetes in youth: the SEARCH Case-Control Study. Diabetes Care 2008, 31:1422–1426.CrossRefPubMed Dabelea D, Mayer-Davis EJ, Lamichhane AP, et al.: Association of intrauterine exposure to maternal diabetes and obesity with type 2 diabetes in youth: the SEARCH Case-Control Study. Diabetes Care 2008, 31:1422–1426.CrossRefPubMed
14.
Zurück zum Zitat Dabelea D, D'Agostino RB Jr, Mayer-Davis EJ, et al.: Testing the accelerator hypothesis: body size, beta-cell function, and age at onset of type 1 (autoimmune) diabetes. Diabetes Care 2006, 29:290–294.CrossRefPubMed Dabelea D, D'Agostino RB Jr, Mayer-Davis EJ, et al.: Testing the accelerator hypothesis: body size, beta-cell function, and age at onset of type 1 (autoimmune) diabetes. Diabetes Care 2006, 29:290–294.CrossRefPubMed
15.
Zurück zum Zitat Greenbaum CJ, Anderson AM, Dolan LM, et al.: Preservation of beta-cell function in autoantibody-positive youth with diabetes. Diabetes Care 2009, 32:1839–1844.CrossRefPubMed Greenbaum CJ, Anderson AM, Dolan LM, et al.: Preservation of beta-cell function in autoantibody-positive youth with diabetes. Diabetes Care 2009, 32:1839–1844.CrossRefPubMed
16.
Zurück zum Zitat Maahs DM, Snively BM, Bell RA, et al.: Higher prevalence of elevated albumin excretion in youth with type 2 than type 1 diabetes: the SEARCH for Diabetes in Youth study. Diabetes Care 2007, 30:2593–2598.CrossRefPubMed Maahs DM, Snively BM, Bell RA, et al.: Higher prevalence of elevated albumin excretion in youth with type 2 than type 1 diabetes: the SEARCH for Diabetes in Youth study. Diabetes Care 2007, 30:2593–2598.CrossRefPubMed
17.
Zurück zum Zitat Rewers A, Klingensmith G, Davis C, et al.: Presence of diabetic ketoacidosis at diagnosis of diabetes mellitus in youth: the Search for Diabetes in Youth Study. Pediatrics 2008,121:e1258–e1266.CrossRefPubMed Rewers A, Klingensmith G, Davis C, et al.: Presence of diabetic ketoacidosis at diagnosis of diabetes mellitus in youth: the Search for Diabetes in Youth Study. Pediatrics 2008,121:e1258–e1266.CrossRefPubMed
18.
Zurück zum Zitat SEARCH Study Group: SEARCH for Diabetes in Youth: a multicenter study of the prevalence, incidence and classification of diabetes mellitus in youth. Control Clin Trials 2004, 25:458–471.CrossRef SEARCH Study Group: SEARCH for Diabetes in Youth: a multicenter study of the prevalence, incidence and classification of diabetes mellitus in youth. Control Clin Trials 2004, 25:458–471.CrossRef
19.
Zurück zum Zitat The SEARCH for Diabetes in Youth Study Group, Liese AD, D'Agostino RB Jr, et al.: The burden of diabetes mellitus among U.S. youth: prevalence estimates from the SEARCH for Diabetes in Youth Study. Pediatrics 2006, 118:1510–1518. The SEARCH for Diabetes in Youth Study Group, Liese AD, D'Agostino RB Jr, et al.: The burden of diabetes mellitus among U.S. youth: prevalence estimates from the SEARCH for Diabetes in Youth Study. Pediatrics 2006, 118:1510–1518.
20.
Zurück zum Zitat •• Writing Group for the SEARCH for Diabetes in Youth Study Group, Dabelea D, Bell RA, et al.: Incidence of diabetes in youth in the United States. JAMA 2007, 297:2716–2724. This paper presents the baseline incidence rates of T1D and T2D in youth less than 20 years of age in the U.S. Since 2002, approximately 5.5 million children less than 20 years of age have been under surveillance each year by SEARCH research centers to estimate diabetes incidence by type, age, sex, and race/ethnicity. SEARCH estimated that annually 15,000 youth are diagnosed with T1D, and 3700 youth are diagnosed with T2D. Additionally, SEARCH data indicate that diabetes prevalence and incidence vary across major racial/ethnic groups. •• Writing Group for the SEARCH for Diabetes in Youth Study Group, Dabelea D, Bell RA, et al.: Incidence of diabetes in youth in the United States. JAMA 2007, 297:2716–2724. This paper presents the baseline incidence rates of T1D and T2D in youth less than 20 years of age in the U.S. Since 2002, approximately 5.5 million children less than 20 years of age have been under surveillance each year by SEARCH research centers to estimate diabetes incidence by type, age, sex, and race/ethnicity. SEARCH estimated that annually 15,000 youth are diagnosed with T1D, and 3700 youth are diagnosed with T2D. Additionally, SEARCH data indicate that diabetes prevalence and incidence vary across major racial/ethnic groups.
21.
Zurück zum Zitat Rewers M, Norris J, Dabelea D: Epidemiology of type 1 diabetes mellitus. Adv Exp Med Biol 2004, 552:219–246.PubMed Rewers M, Norris J, Dabelea D: Epidemiology of type 1 diabetes mellitus. Adv Exp Med Biol 2004, 552:219–246.PubMed
22.
Zurück zum Zitat Rewers M, LaPorte R, Walczak M, et al.: Apparent epidemic of insulin-dependent diabetes mellitus in midwestern Poland. Diabetes 1987, 36:106–113.CrossRefPubMed Rewers M, LaPorte R, Walczak M, et al.: Apparent epidemic of insulin-dependent diabetes mellitus in midwestern Poland. Diabetes 1987, 36:106–113.CrossRefPubMed
23.
Zurück zum Zitat Nystrom L, Dahlquist G, Rewers M, Wall S: The Swedish childhood diabetes study. An analysis of the temporal variation in diabetes incidence 1978–1987. Int J Epidemiol 1990, 19:141–146.CrossRefPubMed Nystrom L, Dahlquist G, Rewers M, Wall S: The Swedish childhood diabetes study. An analysis of the temporal variation in diabetes incidence 1978–1987. Int J Epidemiol 1990, 19:141–146.CrossRefPubMed
24.
Zurück zum Zitat Tuomilehto J, Virtala E, Karvonen M, et al.: Increase in incidence of insulin-dependent diabetes mellitus among children in Finland. Int J Epidemiol 1995, 24:984–992.CrossRefPubMed Tuomilehto J, Virtala E, Karvonen M, et al.: Increase in incidence of insulin-dependent diabetes mellitus among children in Finland. Int J Epidemiol 1995, 24:984–992.CrossRefPubMed
25.
Zurück zum Zitat Tuomilehto J, Rewers M, Reunanen A, et al.: Increasing trend in type 1 (insulin-dependent) diabetes mellitus in childhood in Finland. Analysis of age, calendar time and birth cohort effects during 1965 to 1984. Diabetologia 1991, 34:282–287.CrossRefPubMed Tuomilehto J, Rewers M, Reunanen A, et al.: Increasing trend in type 1 (insulin-dependent) diabetes mellitus in childhood in Finland. Analysis of age, calendar time and birth cohort effects during 1965 to 1984. Diabetologia 1991, 34:282–287.CrossRefPubMed
26.
Zurück zum Zitat Dokheel TM: An epidemic of childhood diabetes in the United States? Diabetes Care 1993, 16:1606–1611.CrossRefPubMed Dokheel TM: An epidemic of childhood diabetes in the United States? Diabetes Care 1993, 16:1606–1611.CrossRefPubMed
27.
Zurück zum Zitat Scott RS, Brown LJ, Darlow BA, et al.: Temporal variation in incidence of IDDM in Canterbury, New Zealand. Diabetes Care 1992, 15:895–899.CrossRefPubMed Scott RS, Brown LJ, Darlow BA, et al.: Temporal variation in incidence of IDDM in Canterbury, New Zealand. Diabetes Care 1992, 15:895–899.CrossRefPubMed
28.
Zurück zum Zitat Bruno G, Merletti F, De Salvia A, et al.: Comparison of incidence of insulin-dependent diabetes mellitus in children and young adults in the Province of Turin, Italy, 1984-91. Piedmont Study Group for Diabetes Epidemiology. Diabet Med 1997, 14:964–969.CrossRefPubMed Bruno G, Merletti F, De Salvia A, et al.: Comparison of incidence of insulin-dependent diabetes mellitus in children and young adults in the Province of Turin, Italy, 1984-91. Piedmont Study Group for Diabetes Epidemiology. Diabet Med 1997, 14:964–969.CrossRefPubMed
29.
Zurück zum Zitat Padaiga Z, Tuomilehto J, Karvonen M, et al.: Incidence trends in childhood onset IDDM in four countries around the Baltic sea during 1983–1992. Diabetologia 1997, 40:187–192.CrossRefPubMed Padaiga Z, Tuomilehto J, Karvonen M, et al.: Incidence trends in childhood onset IDDM in four countries around the Baltic sea during 1983–1992. Diabetologia 1997, 40:187–192.CrossRefPubMed
30.
Zurück zum Zitat LaPorte RE, Fishbein HA, Drash AL, Kuller LH: The Pittsburgh insulin-dependent diabetes mellitus (IDDM) registry. The incidence of insulin-dependent diabetes mellitus in Allegheny County, Pennsylvania (1965–1976). Diabetes 1981, 30:279–284. LaPorte RE, Fishbein HA, Drash AL, Kuller LH: The Pittsburgh insulin-dependent diabetes mellitus (IDDM) registry. The incidence of insulin-dependent diabetes mellitus in Allegheny County, Pennsylvania (1965–1976). Diabetes 1981, 30:279–284.
31.
Zurück zum Zitat Kostraba JN, Gay EC, Cai Y, et al.: Incidence of insulin-dependent diabetes mellitus in Colorado. Epidemiology 1992, 3:232–238.CrossRefPubMed Kostraba JN, Gay EC, Cai Y, et al.: Incidence of insulin-dependent diabetes mellitus in Colorado. Epidemiology 1992, 3:232–238.CrossRefPubMed
32.
Zurück zum Zitat Onkamo P, Vaananen S, Karvonen M, Tuomilehto J: Worldwide increase in incidence of type I diabetes—the analysis of the data on published incidence trends. Diabetologia 1999, 42:1395–1403.CrossRefPubMed Onkamo P, Vaananen S, Karvonen M, Tuomilehto J: Worldwide increase in incidence of type I diabetes—the analysis of the data on published incidence trends. Diabetologia 1999, 42:1395–1403.CrossRefPubMed
33.
Zurück zum Zitat LaPorte RE, Matsushima M, Chang YF: Prevalence and incidence of insulin-dependent diabetes. Bethesda, MD: National Institutes of Health; 1995 (NIH publ. no. 95–1468). LaPorte RE, Matsushima M, Chang YF: Prevalence and incidence of insulin-dependent diabetes. Bethesda, MD: National Institutes of Health; 1995 (NIH publ. no. 95–1468).
34.
Zurück zum Zitat Bell RA, Mayer-Davis EJ, Beyer JW, et al.: Diabetes in non-Hispanic white youth. prevalence, incidence and clinical characteristics: The SEARCH for Diabetes in Youth Study. Diabetes Care 2009, 32:S102–S111.CrossRefPubMed Bell RA, Mayer-Davis EJ, Beyer JW, et al.: Diabetes in non-Hispanic white youth. prevalence, incidence and clinical characteristics: The SEARCH for Diabetes in Youth Study. Diabetes Care 2009, 32:S102–S111.CrossRefPubMed
35.
Zurück zum Zitat Dabelea D, Pettitt DJ, Jones KL, Arslanian SA: Type 2 diabetes mellitus in minority children and adolescents. An emerging problem. Endocrinol Metab Clin North Am 1999, 28:709–729.CrossRefPubMed Dabelea D, Pettitt DJ, Jones KL, Arslanian SA: Type 2 diabetes mellitus in minority children and adolescents. An emerging problem. Endocrinol Metab Clin North Am 1999, 28:709–729.CrossRefPubMed
36.
Zurück zum Zitat Kitagawa T, Mano T, Fujita H: The epidemiology of childhood diabetes mellitus in Tokyo metropolitan area. Tohoku J Exp Med 1983, 141(Suppl):171–179.CrossRefPubMed Kitagawa T, Mano T, Fujita H: The epidemiology of childhood diabetes mellitus in Tokyo metropolitan area. Tohoku J Exp Med 1983, 141(Suppl):171–179.CrossRefPubMed
37.
Zurück zum Zitat Lipton R, Keenan H, Onyemere KU, Freels S: Incidence and onset features of diabetes in African-American and Latino children in Chicago, 1985–1994. Diabetes Metab Res Rev 2002, 18:135–142.CrossRefPubMed Lipton R, Keenan H, Onyemere KU, Freels S: Incidence and onset features of diabetes in African-American and Latino children in Chicago, 1985–1994. Diabetes Metab Res Rev 2002, 18:135–142.CrossRefPubMed
38.
Zurück zum Zitat Pinhas-Hamiel O, Dolan LM, Zeitler PS: Diabetic ketoacidosis among obese African-American adolescents with NIDDM. Diabetes Care 1997, 20:484–486.CrossRefPubMed Pinhas-Hamiel O, Dolan LM, Zeitler PS: Diabetic ketoacidosis among obese African-American adolescents with NIDDM. Diabetes Care 1997, 20:484–486.CrossRefPubMed
39.
Zurück zum Zitat Macaluso CJ, Bauer UE, Deeb LC, et al.: Type 2 diabetes mellitus among Florida children and adolescents, 1994 through 1998. Public Health Rep 2002, 117:373–379.PubMed Macaluso CJ, Bauer UE, Deeb LC, et al.: Type 2 diabetes mellitus among Florida children and adolescents, 1994 through 1998. Public Health Rep 2002, 117:373–379.PubMed
40.
Zurück zum Zitat Scott CR, Smith JM, Cradock MM, Pihoker C: Characteristics of youth-onset noninsulin-dependent diabetes mellitus and insulin-dependent diabetes mellitus at diagnosis. Pediatrics 1997, 100:84–91.CrossRefPubMed Scott CR, Smith JM, Cradock MM, Pihoker C: Characteristics of youth-onset noninsulin-dependent diabetes mellitus and insulin-dependent diabetes mellitus at diagnosis. Pediatrics 1997, 100:84–91.CrossRefPubMed
41.
Zurück zum Zitat Dabelea D, Hanson RL, Bennett PH, et al.: Increasing prevalence of type II diabetes in American Indian children. Diabetologia 1998, 41:904–910.CrossRefPubMed Dabelea D, Hanson RL, Bennett PH, et al.: Increasing prevalence of type II diabetes in American Indian children. Diabetologia 1998, 41:904–910.CrossRefPubMed
42.
Zurück zum Zitat Schober E, Holl RW, Grabert M, et al.: Diabetes mellitus type 2 in childhood and adolescence in Germany and parts of Austria. Eur J Pediatr 2005, 164:705–707.CrossRefPubMed Schober E, Holl RW, Grabert M, et al.: Diabetes mellitus type 2 in childhood and adolescence in Germany and parts of Austria. Eur J Pediatr 2005, 164:705–707.CrossRefPubMed
43.
Zurück zum Zitat Ortega-Rodriguez E, Levy-Marchal C, Tubiana N, et al.: Emergence of type 2 diabetes in an hospital based cohort of children with diabetes mellitus. Diabetes Metab 2001, 27:574–578.PubMed Ortega-Rodriguez E, Levy-Marchal C, Tubiana N, et al.: Emergence of type 2 diabetes in an hospital based cohort of children with diabetes mellitus. Diabetes Metab 2001, 27:574–578.PubMed
44.
Zurück zum Zitat Feltbower RG, McKinney PA, Campbell FM, et al.: Type 2 and other forms of diabetes in 0–30 year olds: a hospital based study in Leeds, UK. Arch Dis Child 2003, 88:676–679.CrossRefPubMed Feltbower RG, McKinney PA, Campbell FM, et al.: Type 2 and other forms of diabetes in 0–30 year olds: a hospital based study in Leeds, UK. Arch Dis Child 2003, 88:676–679.CrossRefPubMed
45.
Zurück zum Zitat Liu LL, Yi JP, Beyer J, et al.: Type 1 and type 2 diabetes in Asian and Pacific Islander U.S. youth: the SEARCH for Diabetes in Youth Study. Diabetes Care 2009, 32(Suppl 2):S133–S140.CrossRefPubMed Liu LL, Yi JP, Beyer J, et al.: Type 1 and type 2 diabetes in Asian and Pacific Islander U.S. youth: the SEARCH for Diabetes in Youth Study. Diabetes Care 2009, 32(Suppl 2):S133–S140.CrossRefPubMed
46.
Zurück zum Zitat Dabelea D, DeGroat J, Sorrelman C, et al.: Diabetes in Navajo youth: prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study. Diabetes Care 2009, 32(Suppl 2):S141–S147.CrossRefPubMed Dabelea D, DeGroat J, Sorrelman C, et al.: Diabetes in Navajo youth: prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study. Diabetes Care 2009, 32(Suppl 2):S141–S147.CrossRefPubMed
47.
Zurück zum Zitat Liu LL, Lawrence JM, Davis C, et al.: Prevalence of overweight and obesity in youth with diabetes in USA: the SEARCH for Diabetes in Youth Study. Pediatr Diabetes 2010, 11:4–11.CrossRefPubMed Liu LL, Lawrence JM, Davis C, et al.: Prevalence of overweight and obesity in youth with diabetes in USA: the SEARCH for Diabetes in Youth Study. Pediatr Diabetes 2010, 11:4–11.CrossRefPubMed
48.
Zurück zum Zitat Mayer-Davis EJ, Beyer J, Bell RA, et al.: Diabetes in African American youth: prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study. Diabetes Care 2009, 32(Suppl 2):S112–S122.CrossRefPubMed Mayer-Davis EJ, Beyer J, Bell RA, et al.: Diabetes in African American youth: prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study. Diabetes Care 2009, 32(Suppl 2):S112–S122.CrossRefPubMed
49.
Zurück zum Zitat Mayer-Davis EJ, Bell RA, Dabelea D, et al.: The many faces of diabetes in American youth: type 1 and type 2 diabetes in five race and ethnic populations: the SEARCH for Diabetes in Youth Study. Diabetes Care 2009, 32(Suppl 2):S99–101.CrossRefPubMed Mayer-Davis EJ, Bell RA, Dabelea D, et al.: The many faces of diabetes in American youth: type 1 and type 2 diabetes in five race and ethnic populations: the SEARCH for Diabetes in Youth Study. Diabetes Care 2009, 32(Suppl 2):S99–101.CrossRefPubMed
50.
Zurück zum Zitat Lawrence JM, Mayer-Davis EJ, Reynolds K, et al.: Diabetes in Hispanic American youth: prevalence, incidence, demographics, and clinical characteristics: the SEARCH for Diabetes in Youth Study. Diabetes Care 2009, 32(Suppl 2):S123–S132.CrossRefPubMed Lawrence JM, Mayer-Davis EJ, Reynolds K, et al.: Diabetes in Hispanic American youth: prevalence, incidence, demographics, and clinical characteristics: the SEARCH for Diabetes in Youth Study. Diabetes Care 2009, 32(Suppl 2):S123–S132.CrossRefPubMed
51.
Zurück zum Zitat Petitti DB, Klingensmith GJ, Bell RA, et al.: Glycemic control in youth with diabetes: the SEARCH for diabetes in Youth Study. J Pediatr 2009, 155:668–672.CrossRefPubMed Petitti DB, Klingensmith GJ, Bell RA, et al.: Glycemic control in youth with diabetes: the SEARCH for diabetes in Youth Study. J Pediatr 2009, 155:668–672.CrossRefPubMed
52.
Zurück zum Zitat Patrick SL, Kadohiro JK, Waxman SH, et al.: IDDM incidence in a multiracial population. The Hawaii IDDM Registry, 1980–1990. Diabetes Care 1997, 20:983–987.CrossRefPubMed Patrick SL, Kadohiro JK, Waxman SH, et al.: IDDM incidence in a multiracial population. The Hawaii IDDM Registry, 1980–1990. Diabetes Care 1997, 20:983–987.CrossRefPubMed
53.
Zurück zum Zitat Kershnar AK, Daniels SR, Imperatore G, et al.: Lipid abnormalities are prevalent in youth with type 1 and type 2 diabetes: the SEARCH for Diabetes in Youth Study. J Pediatr 2006, 149:314–319.CrossRefPubMed Kershnar AK, Daniels SR, Imperatore G, et al.: Lipid abnormalities are prevalent in youth with type 1 and type 2 diabetes: the SEARCH for Diabetes in Youth Study. J Pediatr 2006, 149:314–319.CrossRefPubMed
54.
Zurück zum Zitat Albers JJ, Marcovina SM, Imperatore G, et al.: Prevalence and determinants of elevated apolipoprotein B and dense LDL in youths with type 1 and type 2 diabetes. J Clin Endocrinol Metab 2008, 93:735–742.CrossRefPubMed Albers JJ, Marcovina SM, Imperatore G, et al.: Prevalence and determinants of elevated apolipoprotein B and dense LDL in youths with type 1 and type 2 diabetes. J Clin Endocrinol Metab 2008, 93:735–742.CrossRefPubMed
55.
Zurück zum Zitat Petitti DB, Imperatore G, Palla SL, et al.: Serum lipids and glucose control: the SEARCH for Diabetes in Youth study. Arch Pediatr Adolesc Med 2007, 161:159–165.CrossRefPubMed Petitti DB, Imperatore G, Palla SL, et al.: Serum lipids and glucose control: the SEARCH for Diabetes in Youth study. Arch Pediatr Adolesc Med 2007, 161:159–165.CrossRefPubMed
56.
Zurück zum Zitat Rodriguez BL, Dabelea D, Liese AD, et al.: Prevalence and correlates of elevated blood pressure among youth with diabetes: the SEARCH for Diabetes in Youth Study. J Pediatr 2010 Apr 13 [Epub ahead of print]. Rodriguez BL, Dabelea D, Liese AD, et al.: Prevalence and correlates of elevated blood pressure among youth with diabetes: the SEARCH for Diabetes in Youth Study. J Pediatr 2010 Apr 13 [Epub ahead of print].
57.
Zurück zum Zitat Mayer-Davis EJ, Nichols M, Liese AD, et al.: Dietary intake among youth with diabetes: the SEARCH for Diabetes in Youth Study. J Am Diet Assoc 2006, 106:689–697.CrossRefPubMed Mayer-Davis EJ, Nichols M, Liese AD, et al.: Dietary intake among youth with diabetes: the SEARCH for Diabetes in Youth Study. J Am Diet Assoc 2006, 106:689–697.CrossRefPubMed
58.
Zurück zum Zitat Gunther AL, Liese AD, Bell RA, et al.: Association between the dietary approaches to hypertension diet and hypertension in youth with diabetes mellitus. Hypertension 2009, 53:6–12.CrossRefPubMed Gunther AL, Liese AD, Bell RA, et al.: Association between the dietary approaches to hypertension diet and hypertension in youth with diabetes mellitus. Hypertension 2009, 53:6–12.CrossRefPubMed
59.
Zurück zum Zitat Libman IM, Pietropaolo M, Arslanian SA, et al.: Evidence for heterogeneous pathogenesis of insulin-treated diabetes in black and white children. Diabetes Care 2003, 26:2876–2882.CrossRefPubMed Libman IM, Pietropaolo M, Arslanian SA, et al.: Evidence for heterogeneous pathogenesis of insulin-treated diabetes in black and white children. Diabetes Care 2003, 26:2876–2882.CrossRefPubMed
60.
Zurück zum Zitat Wilkin TJ: The accelerator hypothesis: weight gain as the missing link between type I and type II diabetes. Diabetologia 2001, 44:914–922.CrossRefPubMed Wilkin TJ: The accelerator hypothesis: weight gain as the missing link between type I and type II diabetes. Diabetologia 2001, 44:914–922.CrossRefPubMed
61.
Zurück zum Zitat Larsson HE, Hansson G, Carlsson A, et al.: Children developing type 1 diabetes before 6 years of age have increased linear growth independent of HLA genotypes. Diabetologia 2008, 51:1623–1630.CrossRefPubMed Larsson HE, Hansson G, Carlsson A, et al.: Children developing type 1 diabetes before 6 years of age have increased linear growth independent of HLA genotypes. Diabetologia 2008, 51:1623–1630.CrossRefPubMed
62.
Zurück zum Zitat Lamb MM, Yin X, Zerbe GO, et al.: Height growth velocity, islet autoimmunity and type 1 diabetes development: the Diabetes Autoimmunity Study in the Young. Diabetologia 2009, 52:2064–2071.CrossRefPubMed Lamb MM, Yin X, Zerbe GO, et al.: Height growth velocity, islet autoimmunity and type 1 diabetes development: the Diabetes Autoimmunity Study in the Young. Diabetologia 2009, 52:2064–2071.CrossRefPubMed
63.
Zurück zum Zitat Knerr I, Wolf J, Reinehr T, et al.: The ‘accelerator hypothesis’: relationship between weight, height, body mass index and age at diagnosis in a large cohort of 9,248 German and Austrian children with type 1 diabetes mellitus. Diabetologia 2005, 48:2501–2504.CrossRefPubMed Knerr I, Wolf J, Reinehr T, et al.: The ‘accelerator hypothesis’: relationship between weight, height, body mass index and age at diagnosis in a large cohort of 9,248 German and Austrian children with type 1 diabetes mellitus. Diabetologia 2005, 48:2501–2504.CrossRefPubMed
64.
Zurück zum Zitat Betts P, Mulligan J, Ward P, et al.: Increasing body weight predicts the earlier onset of insulin-dependent diabetes in childhood: testing the ‘accelerator hypothesis’ (2). Diabet Med 2005, 22:144–151.CrossRefPubMed Betts P, Mulligan J, Ward P, et al.: Increasing body weight predicts the earlier onset of insulin-dependent diabetes in childhood: testing the ‘accelerator hypothesis’ (2). Diabet Med 2005, 22:144–151.CrossRefPubMed
65.
Zurück zum Zitat Lawrence JM, Standiford DA, Loots B, et al.: Prevalence and correlates of depressed mood among youth with diabetes: the SEARCH for Diabetes in Youth study. Pediatrics 2006, 117:1348–1358.CrossRefPubMed Lawrence JM, Standiford DA, Loots B, et al.: Prevalence and correlates of depressed mood among youth with diabetes: the SEARCH for Diabetes in Youth study. Pediatrics 2006, 117:1348–1358.CrossRefPubMed
66.
Zurück zum Zitat Naughton MJ, Ruggiero AM, Lawrence JM, et al.: Health-related quality of life of children and adolescents with type 1 or type 2 diabetes: the SEARCH for Diabetes in Youth Study. Arch Pediatr Adolesc Med 2008, 162:649–657.CrossRefPubMed Naughton MJ, Ruggiero AM, Lawrence JM, et al.: Health-related quality of life of children and adolescents with type 1 or type 2 diabetes: the SEARCH for Diabetes in Youth Study. Arch Pediatr Adolesc Med 2008, 162:649–657.CrossRefPubMed
67.
Zurück zum Zitat Mayer-Davis EJ, Dabelea D, Lamichhane AP, et al.: Breast-feeding and type 2 diabetes in youth of three ethnic groups: the SEARCH for diabetes in youth case-control study. Diabetes Care 2008, 31:470–475.CrossRefPubMed Mayer-Davis EJ, Dabelea D, Lamichhane AP, et al.: Breast-feeding and type 2 diabetes in youth of three ethnic groups: the SEARCH for diabetes in youth case-control study. Diabetes Care 2008, 31:470–475.CrossRefPubMed
68.
Zurück zum Zitat West NA, Hamman RF, Mayer-Davis EJ, et al.: Cardiovascular risk factors among youth with and without type 2 diabetes: differences and possible mechanisms. Diabetes Care 2009, 32:175–180.CrossRefPubMed West NA, Hamman RF, Mayer-Davis EJ, et al.: Cardiovascular risk factors among youth with and without type 2 diabetes: differences and possible mechanisms. Diabetes Care 2009, 32:175–180.CrossRefPubMed
69.
Zurück zum Zitat Gilliam LK, Pihoker C, Ellard S, et al.: Unrecognized Maturity-Onset Diabetes of the Young (MODY) due to HNF1-alpha mutations in the SEARCH for Diabetes in Youth Study. Diabetes 2007, 56(Suppl 1):287–OR. Gilliam LK, Pihoker C, Ellard S, et al.: Unrecognized Maturity-Onset Diabetes of the Young (MODY) due to HNF1-alpha mutations in the SEARCH for Diabetes in Youth Study. Diabetes 2007, 56(Suppl 1):287–OR.
70.
Zurück zum Zitat Thomas DB: Alternatives to a national system of population-based state cancer registries. Am J Public Health 2002, 92:1064–1066.CrossRefPubMed Thomas DB: Alternatives to a national system of population-based state cancer registries. Am J Public Health 2002, 92:1064–1066.CrossRefPubMed
Metadaten
Titel
The Value of National Diabetes Registries: SEARCH for Diabetes in Youth Study
verfasst von
Dana Dabelea
Elizabeth J. Mayer-Davis
Giuseppina Imperatore
Publikationsdatum
01.10.2010
Verlag
Current Science Inc.
Erschienen in
Current Diabetes Reports / Ausgabe 5/2010
Print ISSN: 1534-4827
Elektronische ISSN: 1539-0829
DOI
https://doi.org/10.1007/s11892-010-0135-1

Weitere Artikel der Ausgabe 5/2010

Current Diabetes Reports 5/2010 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

„Überwältigende“ Evidenz für Tripeltherapie beim metastasierten Prostata-Ca.

22.05.2024 Prostatakarzinom Nachrichten

Patienten mit metastasiertem hormonsensitivem Prostatakarzinom sollten nicht mehr mit einer alleinigen Androgendeprivationstherapie (ADT) behandelt werden, mahnt ein US-Team nach Sichtung der aktuellen Datenlage. Mit einer Tripeltherapie haben die Betroffenen offenbar die besten Überlebenschancen.

So sicher sind Tattoos: Neue Daten zur Risikobewertung

22.05.2024 Melanom Nachrichten

Das größte medizinische Problem bei Tattoos bleiben allergische Reaktionen. Melanome werden dadurch offensichtlich nicht gefördert, die Farbpigmente könnten aber andere Tumoren begünstigen.

CAR-M-Zellen: Warten auf das große Fressen

22.05.2024 Onkologische Immuntherapie Nachrichten

Auch myeloide Immunzellen lassen sich mit chimären Antigenrezeptoren gegen Tumoren ausstatten. Solche CAR-Fresszell-Therapien werden jetzt für solide Tumoren entwickelt. Künftig soll dieser Prozess nicht mehr ex vivo, sondern per mRNA im Körper der Betroffenen erfolgen.

Frühzeitige HbA1c-Kontrolle macht sich lebenslang bemerkbar

22.05.2024 Typ-2-Diabetes Nachrichten

Menschen mit Typ-2-Diabetes von Anfang an intensiv BZ-senkend zu behandeln, wirkt sich positiv auf Komplikationen und Mortalität aus – und das offenbar lebenslang, wie eine weitere Nachfolgeuntersuchung der UKPD-Studie nahelegt.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.