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18.07.2018 | EDITORIAL

Thiamine Therapy for Heart Failure: a Promise or Fiction?

Erschienen in: Cardiovascular Drugs and Therapy | Ausgabe 4/2018

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Thiamine (vitamin B1) is an essential water-soluble vitamin required for cellular energy production. Thiamine pyrophosphate (TPP) is a coenzyme in the pentose phosphate pathway for transketolation of glucose-6-phosphate to ribose-5-phosphate. In the Kreb’s cycle, TPP is needed for the functioning of the pyruvate dehydrogenase complex (which converts pyruvate to acetyl CoA) and alpha-ketoglutarate dehydrogenase (which converts alpha-ketoglutarate to succinate). These reactions are needed for aerobic metabolism and production of ATP. Thiamine also helps in the conduction of nerve impulses, independent of its coenzyme functions. It is important for maintenance of nerve membrane stability and modulates membrane ion channels for efficient nerve conduction [1]. …

Bâ A. Metabolic and structural role of thiamine in nervous tissues. Cell Mol Neurobiol. 2008;28(7):923–31.CrossRefPubMed

Young RC, Blass JP. Iatrogenic nutritional deficiencies. Annu Rev Nutr. 1982;2:201–27.CrossRefPubMed

Anderson S, Vickery C, Nicol A. Adult thiamine requirements and the continuing need to fortify processed cereals. Lancet. 1986;328(8498):85–9.CrossRef

DiNicolantonio JJ, Liu J, O’Keefe JH. Thiamine and cardiovascular disease: a literature review. Prog Cardiovasc Dis. 2018;

Pfitzenmeyer P, Guilland JC, d’Athis P, Petit-Marnier C, Gaudet M. Thiamine status of elderly patients with cardiac failure including the effects of supplementation. Int J Vitam Nutr Res. 1994;64(2):113–8.PubMed

Oliveira FA, Guatimosim S, Castro CH, Galan DT, Lauton-Santos S, Ribeiro AM, et al. Abolition of reperfusion-induced arrhythmias in hearts from thiamine-deficient rats. Am J Phys Heart Circ Phys. 2007;293(1):H401.

Dabar G, Harmouche C, Habr B, Riachi M, Jaber B. Shoshin beriberi in critically-ill patients: case series. Nutr J. 2015;14(1):51.CrossRefPubMedPubMedCentral

Lei Y, Zheng M, Huang W, Zhang J, Lu Y. Wet beriberi with multiple organ failure remarkably reversed by thiamine administration: a case report and literature review. Medicine (Baltimore). 2018;97(9):e0010.

Benjamin EJ, Blaha MJ, Chiuve SE, Cushman M, Das SR, Deo R, et al. Heart disease and stroke statistics—2017 update: a report from the American Heart Association. Circulation. 2017;135(10):e603.CrossRef

10.

Jain A, Mehta R, Al-Ani M, Hill JA, Winchester DE. Determining the role of thiamine deficiency in systolic heart failure: a meta-analysis and systematic review. J Card Fail. 2015;21(12):1000–7.CrossRefPubMed

11.

Katta N, Balla S, Alpert MA. Does long-term furosemide therapy cause thiamine deficiency in patients with heart failure? A focused review. Am J Med. 2016;129(7):753.e11.CrossRef

12.

Seligmann H, Halkin H, Rauchfleisch S, Kaufmann N, Tal R, Motro M, et al. Thiamine deficiency in patients with congestive heart failure receiving long-term furosemide therapy: a pilot study. Am J Med. 1991;91(2):151–5.CrossRefPubMed

13.

Rieck J, Halkin H, Almog S, Seligman H, Lubetsky A, Olchovsky D, et al. Urinary loss of thiamine is increased by low doses of furosemide in healthy volunteers. J Lab Clin Med. 1999;134(3):238–43.CrossRefPubMed

14.

Zenuk C, Healey J, Donnelly J, Vaillancourt R, Almalki Y, Smith S. Thiamine deficiency in congestive heart failure patients receiving long term furosemide therapy. Can J Clin Pharmacol. 2003;10(4):184–8.PubMed

15.

Rocha RM, Silva GV, de Albuquerque DC, Tura BR, Albanesi Filho FM. Influence of spironolactone therapy on thiamine blood levels in patients with heart failure. Arq Bras Cardiol. 2008;90(5):324–8.CrossRefPubMed

16.

Roman-Campos D, Campos AC, Gioda CR, Campos PP, Medeiros M, Cruz JS. Cardiac structural changes and electrical remodeling in a thiamine-deficiency model in rats. Life Sci. 2009;84(23–24):817–24.CrossRefPubMed

17.

Gioda CR, de Oliveira Barreto T, Primola-Gomes TN, de Lima DC, Campos PP, Capettini L d S, et al. Cardiac oxidative stress is involved in heart failure induced by thiamine deprivation in rats. Am J Phys Heart Circ Phys. 2010;298(6):H2045.

18.

Jikrona R, Suharjono S, Ahmad A. Thiamine supplement therapy improves ejection fraction value in stage ii heart failure patients. Folia Medica Indonesiana. 2017;53(2):139–43.CrossRef

19.

Shimon H, Almog S, Vered Z, Seligmann H, Shefi M, Peleg E, et al. Improved left ventricular function after thiamine supplementation in patients with congestive heart failure receiving long-term furosemide therapy. Am J Med. 1995;98(5):485–90.CrossRefPubMed

20.

Schoenenberger A, Schoenenberger-Berzins R, der Maur C, Suter P, Vergopoulos A, Erne P. Thiamine supplementation in symptomatic chronic heart failure: a randomized, double-blind, placebo-controlled, cross-over pilot study. Clin Res Cardiol. 2012;101(3):159–64.CrossRefPubMed

21.

Dinicolantonio JJ, Lavie CJ, Niazi AK, O’Keefe JH, Hu T. Effects of thiamine on cardiac function in patients with systolic heart failure: systematic review and metaanalysis of randomized, double-blind, placebo-controlled trials. Ochsner J. 2013;13(4):495–9.PubMedPubMedCentral

22.

Mousavi M, Namazi S, Avadi M, Amirahmadi M, Salehifar D. Thiamine supplementation in patients with chronic heart failure receiving optimum medical treatment. J Cardiol Curr Res. 2017;9(2):00316.

23.

Smithline HA, Donnino M, Greenblatt DJ. Pharmacokinetics of high-dose oral thiamine hydrochloride in healthy subjects. BMC Clin Pharmacol. 2012;12(1):4.CrossRefPubMedPubMedCentral

Titel: Thiamine Therapy for Heart Failure: a Promise or Fiction?
Publikationsdatum: 18.07.2018
Erschienen in: Cardiovascular Drugs and Therapy / Ausgabe 4/2018
Print ISSN: 0920-3206
Elektronische ISSN: 1573-7241
DOI: https://doi.org/10.1007/s10557-018-6808-8

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