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World Journal of Urology

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05.05.2018 | Original Article

Thulium vapoenucleation of the prostate versus holmium laser enucleation of the prostate for the treatment of large volume prostates: preliminary 6-month safety and efficacy results of a prospective randomized trial

verfasst von: B. Becker, T. R. W. Herrmann, A. J. Gross, C. Netsch

Erschienen in: World Journal of Urology | Ausgabe 10/2018

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Abstract

Purpose

We compared the perioperative and postoperative characteristics of thulium vapoenucleation and holmium laser enucleation of the prostate for the treatment of large volume benign prostatic hyperplasia.

Materials and methods

A total of 94 patients with benign prostatic hyperplasia and a median prostate size of 80 (IQR 46.75–100) cc were either randomized to thulium vapoenucleation or holmium laser enucleation of the prostate. Patients were assessed preoperatively, 1 and 6 months postoperatively.

Results

The median operative time was 60 (IQR 41–79) min without significant differences between the groups. There were no significant differences between the groups regarding catheter time [2 (IQR 2–2) days] and postoperative stay [2 (IQR 2–3) days]. Clavien 1 (13.8%), 2 (3.2%), 3a (2.1%), and Clavien 3b (4.3%) complications occurred without significant differences between the groups. At 6-month follow-up, median maximum flow rate (10.7 vs. 25.9 ml/s), post-void residual urine (100 vs. 6.5 ml), I-PSS (20 vs. 5), quality of life (4 vs. 1), PSA (4.14 vs. 0.71 µg/l), and prostate volume (80 vs. 16 ml) had improved significantly (p < 0.001) compared to baseline without significant differences between the groups. Median PSA decrease was 79.7% (58.8–90.6%) and prostate volume reduction was 74.5% (68.57–87.63%) without differences between the groups. The reoperation rate was zero at 6-month follow-up.

Conclusions

Thulium vapoenucleation and holmium laser enucleation of the prostate are safe and effective procedures for the treatment of large volume benign prostatic hyperplasia. Both procedures give satisfactory micturition improvement with low morbidity and sufficient prostate volume reduction at 6-month follow-up.

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Titel: Thulium vapoenucleation of the prostate versus holmium laser enucleation of the prostate for the treatment of large volume prostates: preliminary 6-month safety and efficacy results of a prospective randomized trial
verfasst von: B. Becker
T. R. W. Herrmann
A. J. Gross
C. Netsch
Publikationsdatum: 05.05.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: World Journal of Urology / Ausgabe 10/2018
Print ISSN: 0724-4983
Elektronische ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-018-2321-8

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Thulium vapoenucleation of the prostate versus holmium laser enucleation of the prostate for the treatment of large volume prostates: preliminary 6-month safety and efficacy results of a prospective randomized trial

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Purpose

Materials and methods

Results

Conclusions

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