Erschienen in:
05.04.2019 | Editorial
Time for a new definition of Parkinson’s disease
verfasst von:
Wolfgang H. Jost, Heinz Reichmann
Erschienen in:
Journal of Neural Transmission
|
Ausgabe 7/2019
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Excerpt
Parkinson’s disease is traditionally defined as a motor disease characterized by the triad of akinesia, rigidity and tremor, whereby bradykinesia is the obligatory symptom for a secure diagnosis. However, in the past 20 years, the non-motor symptoms (NMS) have gained increased attention, although they are still considered “lesser lights” compared to the motor ones, and are still only rarely considered in formulating diagnostic criteria. But importantly: most of the NMS are in fact more frequent than, for example, resting tremor and more severely restrict quality of life through the course of the disease due to the fact that their therapeutic treatment is limited. …